RNA News and Research

RSS

Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Digital warm-start CRISPR assay enables sensitive quantitative detection of SARS-CoV-2 in clinical samples

In a recent medRxiv* preprint paper, researchers from the University of Connecticut Health Center in the United States unveil their digital warm-start CRISPR (WS-CRISPR) method for stringent and sensitive quantitative detection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in clinical samples of patients with coronavirus disease (COVID-19).

24 Nov 2020

The role of micro-RNA in SARS-CoV-2 infection and COVID-19

A team of researchers based in Iran have explored the role of micro-RNA in COVID-19. Their study titled, “The emerging role of microRNAs in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection,” was published in the latest issue of the journal International Immunopharmacology.

24 Nov 2020

Scientists show SARS-CoV-2's viral replication with 3D integrative imaging

A team of researchers at Heidelberg University in Germany have performed a detailed imaging analysis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection to determine how the virus reprograms infected cells.

24 Nov 2020

Aprotinin inhibits SARS-CoV-2 entry and replication in cells cultures

Researchers at the University of Kent in the UK and the Hannover Medical School and Goethe University in Germany have observed that the protease inhibitor aprotinin can inhibit viral replication by preventing SARS-CoV-2 entry into host cells.

24 Nov 2020

SARS-CoV-2's RNA folding structures are potential therapeutic targets, study finds

A team of researchers at Goethe University in Germany has observed the RNA folding structures of the SARS-CoV-2 genome that aids the infection process.

24 Nov 2020

Researchers recommend antibody cocktail to tackle SARS-CoV-2 mutations

A new study released on the medRxiv* preprint server indicates that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent responsible for the current coronavirus disease 2019 (COVID-19) pandemic – is developing multiple mutations that affect neutralization by antibodies.

24 Nov 2020

Researchers use single-cell RNA sequence analysis to address the cornea's healing process

The insulation around nerve cell components in our corneas have unique properties, and little is known about them.

24 Nov 2020

SARS-CoV-2 RNA best preserved in wastewater under freezing conditions

Wastewater surveillance has been reported to be a feasible and efficient way to monitor the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the current COVID-19 pandemic. A recent study draws attention to the need to freeze wastewater samples if the analysis is carried out later rather than immediately.

24 Nov 2020

SARS-CoV-2's spike protein mutations have slowed, study finds

A team of researchers at the School of Information Sciences in Illinois, USA, has revealed the rate of mutation in the 29 proteins that make up the SARS-CoV-2 microbe.

23 Nov 2020

SARS-CoV-2 spike deletion mutations may evade current vaccine candidates, study finds

A thought-provoking new study reports that the anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike antibodies elicited by natural infection may not be able to neutralize emerging strains that display deletion mutations in their genomic RNA.

23 Nov 2020

Greensboro North Carolina Company’s Dedication to Ensuring Laboratories have COVID-19 Supplies Now Offers One-Stop-Shop for PCR Instruments, Extraction Systems and Kits, POC COVID-19 Test Kits, and Supplies.

GREENSBORO, NC — (November 20, 2020) – Greensboro-based, Carolina Liquid Chemistries Corp. (CLC) has been tirelessly working since the beginning of the COVID-19 outbreak to provide high-quality testing kits and instruments to healthcare providers and laboratories as quickly as possible.

From Carolina Liquid Chemistries Corp. 23 Nov 2020

Study on SARS-Cov2 genome may prepare scientists for future ‘SARS-CoV3’ viruses

The genetic code of the SARS-CoV2 virus is exactly 29,902 characters long, strung through a long RNA molecule. It contains information for the production of 27 proteins.

23 Nov 2020

Pomegranate peel extract shows potential as inhibitor of SARS-CoV-2 virus

Researchers led by first author Relja Suručić from the Department of Pharmacognosy, Faculty of Medicine, University of Banja Luka, Banja Luka, Bosnia and Herzegovina, have studied the use of pomegranate peel extracts in preventing infections with SARS-CoV-2.

22 Nov 2020

COVID-19 potentially has negative impacts on male fertility

A review recently published in the Journal of Medical Virology has discussed some of the effects that infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – may have on male fertility.

22 Nov 2020

Inflammatory factors that aggravate COVID-19 may come from adipose tissue

There is growing evidence that adipose tissue plays a key role in the aggravation of COVID-19. One of the theories under investigation is that fat cells (adipocytes) act as a reservoir for SARS-CoV-2 and increase viral load in obese or overweight individuals.

20 Nov 2020

Inexpensive, rapid-turnaround COVID-19 tests could eliminate the virus within weeks

Testing half the population weekly with inexpensive, rapid-turnaround COVID-19 tests would drive the virus toward elimination within weeks-- even if those tests are significantly less sensitive than gold-standard clinical tests, according to a new study published today by University of Colorado Boulder and Harvard University researchers.

20 Nov 2020

New findings could pave the way for more effective, safer and cheaper gene therapy

In a promising advance for affordable, personalized medicine, researchers have used metal-organic frameworks to successfully deliver the genetic snipping tool CRISPR/Cas9 into human cancer cells.

20 Nov 2020

Scientists exploit 'trojan horse' feature in SARS-CoV-2 virus to create antivirals against COVID-19

Scientific analysis of a protein enzyme found in COVID-19 could lead to the development of new drugs to treat the virus, research led by Oxford Brookes University scientists has found.

20 Nov 2020

Specific bacterial sRNA plays key role in symbiosis between Vibrio fischeri and squid

Bacteria living symbiotically within the Hawaiian bobtail squid can direct the host squid to change its normal gene-expression program to make a more inviting home, according to a new study published in PLoS Biology by researchers at the University of Hawai'i (UH) at Mānoa School of Ocean and Earth Science and Technology (SOEST).

20 Nov 2020

Sinovac Biotech's COVID-19 vaccine candidate triggers immune response

Now, Sinovac Biotech's candidate vaccine, CoronaVac, has been found to induce an immune response in healthy adults aged 18–59 years, 28 days post-vaccination. However, the level of antibodies generated was lower than in people who had recovered from the illness.

19 Nov 2020

RNA News and Research

Further Reading

Digital warm-start CRISPR assay enables sensitive quantitative detection of SARS-CoV-2 in clinical samples

The role of micro-RNA in SARS-CoV-2 infection and COVID-19

Scientists show SARS-CoV-2's viral replication with 3D integrative imaging

Aprotinin inhibits SARS-CoV-2 entry and replication in cells cultures

SARS-CoV-2's RNA folding structures are potential therapeutic targets, study finds

Researchers recommend antibody cocktail to tackle SARS-CoV-2 mutations

Researchers use single-cell RNA sequence analysis to address the cornea's healing process

SARS-CoV-2 RNA best preserved in wastewater under freezing conditions

SARS-CoV-2's spike protein mutations have slowed, study finds

SARS-CoV-2 spike deletion mutations may evade current vaccine candidates, study finds

Greensboro North Carolina Company’s Dedication to Ensuring Laboratories have COVID-19 Supplies Now Offers One-Stop-Shop for PCR Instruments, Extraction Systems and Kits, POC COVID-19 Test Kits, and Supplies.

Study on SARS-Cov2 genome may prepare scientists for future ‘SARS-CoV3’ viruses

Pomegranate peel extract shows potential as inhibitor of SARS-CoV-2 virus

COVID-19 potentially has negative impacts on male fertility

Inflammatory factors that aggravate COVID-19 may come from adipose tissue

Inexpensive, rapid-turnaround COVID-19 tests could eliminate the virus within weeks

New findings could pave the way for more effective, safer and cheaper gene therapy

Scientists exploit 'trojan horse' feature in SARS-CoV-2 virus to create antivirals against COVID-19

Specific bacterial sRNA plays key role in symbiosis between Vibrio fischeri and squid

Sinovac Biotech's COVID-19 vaccine candidate triggers immune response

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo