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Researchers discover new and rare skeletal disease

Researchers at Karolinska Institutet in Sweden have discovered a new and rare skeletal disease. In a study published in the journal Nature Medicine they describe the molecular mechanism of the disease, in which small RNA molecules play a role that has never before been observed in a congenital human disease.

25 Feb 2019

Specific gene variation associated with ADHD could be tied to substance addiction

Some variations in the gene LPHN3 -associated with the attention deficit/hyperactivity disorder (ADHD) in kids and adults- could favor likelihood to smoke, consume alcohol, cannabis and other addictive substances, according to an article published in the journal Translational Psychiatry, from the Nature Publishing Group.

25 Feb 2019

Base Pair Biotechnologies to develop point-of-care tests for opioids in newborns

Base Pair Biotechnologies announced today the receipt of a Fast Track Small Business Innovation Research grant from the National Institute on Drug Abuse of the NIH

From Base Pair Biotechnologies, Inc. 25 Feb 2019

Researchers uncover how Gram-negative bacterium delivers toxins that make us sick

Researchers at Binghamton University, State University of New York have uncovered the unique way in which a type of Gram-negative bacterium delivers the toxins that make us sick. Understanding this mechanism may help design better ways to block and eventually control those toxins.

25 Feb 2019

Researchers engineer 'antibody-like' T cell receptors to combat deadly virus

Researchers have engineered "antibody-like" T cell receptors that can specifically stick to cells infected with cytomegalovirus, or CMV, a virus that causes lifelong infection in more than half of all adults by age 40.

23 Feb 2019

New technology platform digitally counts growth factors in single cells

Whether healthy or diseased, human cells exhibit behaviors and processes that are largely dictated by growth factor molecules, which bind to receptors on the cells. For example, growth factors tell the cells to divide, move, and when to die--a process known as apoptosis.

23 Feb 2019

Clinical study shows tolerability and safety of investigational drug in boys with DMD

Patients with Duchenne muscular dystrophy have few treatment options. Medications currently available or in development either target only a subset of DMD patients with a particular genetic mutation or cause significant side effects.

23 Feb 2019

Novel MRI sensor can peer deep into the brain to detect intracellular calcium activity

Calcium is a critical signaling molecule for most cells, and it is especially important in neurons. Imaging calcium in brain cells can reveal how neurons communicate with each other; however, current imaging techniques can only penetrate a few millimeters into the brain.

22 Feb 2019

New study finds how high-fat diets fuel colorectal cancer growth

As cancer death rates drop overall, doctors have noted a frightening anomaly: deaths from colorectal cancer in people under 55 appear to be creeping up. According to the American Cancer Society, deaths in this younger group increased by 1 percent between 2007 and 2016.

22 Feb 2019

Researchers uncover interspecies communication between gut bacteria and host

Bacteria in the gut do far more than help digest food in the stomachs of their hosts, they can also tell the genes in their mammalian hosts what to do.

22 Feb 2019

Innovative compound offers a new therapeutic approach to treat multiple sclerosis

Multiple sclerosis is an autoimmune disease that affects more than 2.3 million people worldwide. This debilitating condition periodically shutters communication between the brain and other parts of the body, resulting in symptoms that range from numbness and tingling in the arms and legs to blindness and paralysis.

22 Feb 2019

Newly designed molecule could benefit people with Friedrich's Ataxia

Skin cells taken from patients with a rare genetic disorder are up to ten times more sensitive to damage from ultraviolet A radiation in laboratory tests, than those from a healthy population, according to new research from the University of Bath.

21 Feb 2019

Phase 1 data reinforce safety profile of new drug for treating Duchenne muscular dystrophy

Patients with Duchenne muscular dystrophy (DMD) have few treatment options. Medications currently available or in development either target only a subset of DMD patients with a particular genetic mutation or cause significant side effects.

21 Feb 2019

Dietary fiber helps to aggregate gut particles, study shows

Food, microbes, and medicine all clump together as they move through our gut. Sticky molecules secreted into our intestines bind the gut particles in the same way that flour holds a ball of dough together.

21 Feb 2019

Intense exercise, fasting and hormones can enhance waste-protein removal, study shows

The body's ability to adapt to changing conditions and shifting physiologic demands is essential to survival. To do so, each cell must be able to dispose of damaged or unnecessary proteins--a quality-control mechanism critical for cellular performance and for the health of the entire organism.

21 Feb 2019

Johns Hopkins scientists find new compound that may prevent reperfusion injury

In a strategic search, Johns Hopkins scientists created and screened a library of 45,000 new compounds containing chemical elements of widely used immune system suppressants, and say they found one that may prevent reperfusion injury, a tissue-damaging and common complication of surgery, heart attack and stroke.

21 Feb 2019

Discovery of potent compound in native California shrub may lead to treatment for Alzheimer's

The medicinal powers of aspirin, digitalis, and the anti-malarial artemisinin all come from plants. A Salk Institute discovery of a potent neuroprotective and anti-inflammatory chemical in a native California shrub may lead to a treatment for Alzheimer's disease based on a compound found in nature.

21 Feb 2019

Why melanoma tumors in the brain may be worse?

Melanoma tumors that have spread to the brain are equipped to thwart immunotherapies and targeted therapies that succeed against tumors growing in other sites.

20 Feb 2019

Scientists demonstrate influence of food odors on proteostasis

The smell of food induces a variety of physiological processes in our body. Thus, the production of saliva and digestive enzymes is stimulated before the actual food intake in order to prepare the gastrointestinal tract for the upcoming digestive process.

20 Feb 2019

New technique could expedite cancer diagnosis, lead to better patient outcomes

The days - or even weeks - spent waiting for the results of a cancer-screening test can feel like an eternity. Especially when early diagnosis and quick action are tied to better outcomes.

20 Feb 2019

Molecule News and Research

Researchers discover new and rare skeletal disease

Specific gene variation associated with ADHD could be tied to substance addiction

Base Pair Biotechnologies to develop point-of-care tests for opioids in newborns

Researchers uncover how Gram-negative bacterium delivers toxins that make us sick

Researchers engineer 'antibody-like' T cell receptors to combat deadly virus

New technology platform digitally counts growth factors in single cells

Clinical study shows tolerability and safety of investigational drug in boys with DMD

Novel MRI sensor can peer deep into the brain to detect intracellular calcium activity

New study finds how high-fat diets fuel colorectal cancer growth

Researchers uncover interspecies communication between gut bacteria and host

Innovative compound offers a new therapeutic approach to treat multiple sclerosis

Newly designed molecule could benefit people with Friedrich's Ataxia

Phase 1 data reinforce safety profile of new drug for treating Duchenne muscular dystrophy

Dietary fiber helps to aggregate gut particles, study shows

Intense exercise, fasting and hormones can enhance waste-protein removal, study shows

Johns Hopkins scientists find new compound that may prevent reperfusion injury

Discovery of potent compound in native California shrub may lead to treatment for Alzheimer's

Why melanoma tumors in the brain may be worse?

Scientists demonstrate influence of food odors on proteostasis

New technique could expedite cancer diagnosis, lead to better patient outcomes

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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