Biochemistry News and Research

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Modulating gene expression using small molecules

The correct functioning of cells relies heavily on the ability to finely control gene expression, a complex process by which the information contained in DNA is copied into RNA to eventually give rise to all the proteins and most of the regulatory molecules in the cell.

2 Jul 2024

New light-activated method targets cancer and inflammatory cells with precision

A new method of precisely targeting troublesome cells for death using light could unlock new understanding of and treatments for cancer and inflammatory diseases, University of Illinois Urbana-Champaign researchers report.

1 Jul 2024

New weakness found in antibiotic-resistant Pseudomonas aeruginosa

Antibiotic resistant bacteria are experts in evolving new strategies to avoid being killed by antibiotics.

1 Jul 2024

Nanorobots with hidden weapons for precision cancer therapy

Researchers at Karolinska Institutet in Sweden have developed nanorobots that kill cancer cells in mice.

1 Jul 2024

Enhancing viral therapy for resistant cancers with a metabolite-drug

When a cancer cell doesn't respond to traditional therapies, doctors may turn to a sort of viral biological warfare, by deploying 'troops' in the form of viral agents that are specifically engineered to target and eliminate cancer cells.

28 Jun 2024

Cell division's hidden safety mechanism may influence cancer growth

Before a cell commits fully to the process of dividing itself into two new cells, it may ensure the appropriateness of its commitment by staying for many hours - sometimes more than a day - in a reversible intermediate state, according to a discovery by researchers at Weill Cornell Medicine. Their revelation of this fundamental feature of biology includes details of its mechanisms and dynamics, which may inform the development of future therapies targeting cancers and other diseases.

27 Jun 2024

Novel genetic predisposition to being overweight or obese identified

Researchers performed a case-control study to compare metabolic changes between individuals homozygous for a loss-of-function genetic variation in small integral membrane protein 1 (SMIM1) and the general population.

25 Jun 2024

UTHealth Houston researchers to study circadian link in severe headaches with $2.4M grant

The link between severe headache disorders headaches and the body's circadian clock in pain timing and thresholds will be studied with a $2.4 million grant from the National Institute of Neurological Disorders and Stroke (NINDS) to UTHealth Houston researchers.

21 Jun 2024

Study uncovers new insights into the main human cold and menthol sensor TRPM8

Chronic pain affects millions worldwide, and current treatments often rely on opioids, which carry risks of addiction and overdose.

21 Jun 2024

Transforming drug discovery with AI

A new AI-powered program will allow researchers to level up their drug discovery efforts.

21 Jun 2024

Using deep learning to design synthetic soluble versions of cell membrane proteins

Many drug and antibody discovery pathways focus on intricately folded cell membrane proteins: when molecules of a drug candidate bind to these proteins, like a key going into a lock, they trigger chemical cascades that alter cellular behavior.

21 Jun 2024

Novel method for 'rationally engineering' enzymes to deliver improved performance

Scientists have prototyped a new method for "rationally engineering" enzymes to deliver improved performance.

20 Jun 2024

Study reveals overactive PKA protein as driver of fibrolamellar carcinoma

It's been enormously difficult to pinpoint the cause of many cancers - and many seem to have more than one origin. Fibrolamellar carcinoma (FLC), however, is one that scientists thought they had nailed down.

18 Jun 2024

Precise protein design offers hope for damaged hearts and kidneys

Using computer-designed proteins, researchers have now shown they are able to direct human stem cells to form new blood vessels in the lab. This milestone in regenerative medicine offers new hope for repairing damaged hearts, kidneys, and other organs.

18 Jun 2024

Revolutionary anti-ceramide immunotherapy could prevent blindness in diabetic patients

Patients with diabetes face a host of potential health problems as they work to manage the chronic disease.

17 Jun 2024

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

In our latest interview, News Medical speaks with SCIEX, a global leader in life science analytical technologies, about their exciting announcements at ASMS, the SCIEX 7500+ System, and how they utilize AI quantitation software to streamline solutions.

From SCIEX 14 Jun 2024

UNF researchers awarded U.S. patent for targeted cancer-fighting compound

Three University of North Florida (UNF) researchers have been awarded a U.S. patent for a targeted cancer-fighting compound, or peptoid, that the team has discovered targets certain breast, colon and lung cancers and stops them from progressing.

12 Jun 2024

UD researchers pioneer universal, economical method for proteomics sample preparation

Proteins are workhorses that carry out most of the biological functions in our cells. While the genes we inherit from our parents, our so-called genome, are fixed and usually remain unchanged throughout our lives, proteins in our bodies are constantly changing, as we age, under different health conditions and upon stimulation, such as with medical treatment.

11 Jun 2024

Antibacterial lipopeptide shown to be highly effective in killing Staphylococcus aureus

A novel antibacterial lipopeptide produced by the bacterium Serratia marcescens has been shown to be highly effective in killing Staphylococcus aureus – one of the most important pathogens occurring in humans.

6 Jun 2024

Facial temperature can predict heart disease with higher accuracy than current methods

Researchers found that facial infrared thermography can predict coronary artery disease more accurately than traditional pretest probability tools, using deep-learning algorithms to analyze temperature patterns.

6 Jun 2024

Biochemistry News and Research

Modulating gene expression using small molecules

New light-activated method targets cancer and inflammatory cells with precision

New weakness found in antibiotic-resistant Pseudomonas aeruginosa

Nanorobots with hidden weapons for precision cancer therapy

Enhancing viral therapy for resistant cancers with a metabolite-drug

Cell division's hidden safety mechanism may influence cancer growth

Novel genetic predisposition to being overweight or obese identified

UTHealth Houston researchers to study circadian link in severe headaches with $2.4M grant

Study uncovers new insights into the main human cold and menthol sensor TRPM8

Transforming drug discovery with AI

Using deep learning to design synthetic soluble versions of cell membrane proteins

Novel method for 'rationally engineering' enzymes to deliver improved performance

Study reveals overactive PKA protein as driver of fibrolamellar carcinoma

Precise protein design offers hope for damaged hearts and kidneys

Revolutionary anti-ceramide immunotherapy could prevent blindness in diabetic patients

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

UNF researchers awarded U.S. patent for targeted cancer-fighting compound

UD researchers pioneer universal, economical method for proteomics sample preparation

Antibacterial lipopeptide shown to be highly effective in killing Staphylococcus aureus

Facial temperature can predict heart disease with higher accuracy than current methods

Binding kinetics in drug discovery eBook eBook

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