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Does intermittent fasting help you lose more weight? Evidence review finds no clear advantage

A Cochrane systematic review of 22 randomized trials involving 1,995 adults with overweight or obesity found intermittent fasting produces weight loss comparable to traditional calorie restriction. Evidence suggests little additional benefit for quality of life or adverse effects, with overall certainty ranging from low to moderate and long-term effects still unclear.

17 Feb 2026

Myopia may be driven by prolonged close-up focus in low-light environments

For years, rising rates of myopia - or nearsightedness - have been widely attributed to increased screen time, especially among children and young adults.

17 Feb 2026

Chronic inflammation shapes cancer progression and immunotherapy response

Chronic inflammation is both a driver and suppressor of cancer depending on context. Key players-NF-κB, IL-6, STAT3, TAMs, MDSCs, and Tregs-orchestrate a tumor-permissive microenvironment.

16 Feb 2026

OVACell project pioneers viral target immunotherapy for ovarian cancer

A small team at OVACell is fighting ovarian cancer with hidden viral sequences and advanced immunotherapies.

16 Feb 2026

Nasal COVID vaccine boost increases IgA responses linked to variant neutralisation

Intranasal boosting after prior intramuscular COVID vaccination induced strong mucosal IgA responses in a small human cohort. These antibodies showed markedly enhanced neutralising activity against Omicron variants and evidence of immune memory reprogramming toward mucosal protection.

15 Feb 2026

Vitamin A and thyroid hormones in the retina shape fetal vision

Humans develop sharp vision during early fetal development thanks to an interplay between a vitamin A derivative and thyroid hormones in the retina, Johns Hopkins University scientists have found.

13 Feb 2026

Review compares surgical and neurostimulation outcomes in temporal lobe epilepsy

Temporal lobe epilepsy (TLE) is the most common form of focal epilepsy, affecting a significant proportion of patients who develop drug-resistant epilepsy.

13 Feb 2026

Engineered Listeria boosts innate immunity against cancer

After nearly 40 years of research on how Listeria bacteria manipulate our cells and battle our immune system to cause listeriosis, Daniel Portnoy and his colleagues have discovered a way to turn the bacteria into a potent booster of the immune system - and a potential weapon against cancer.

13 Feb 2026

Diacerein shows promise as disease-modifying therapy in rheumatoid arthritis

Announcing a new publication for Acta Materia Medica journal. Diacerein, an anthraquinone derivative, is emerging as a promising disease-modifying agent in rheumatoid arthritis (RA), because of its potent anti-inflammatory and chondroprotective actions.

13 Feb 2026

Thermodynamic insights into histamine H1 receptor ligand binding

G-protein-coupled receptors (GPCRs) are one of the largest families of cell surface proteins in the human body that recognize hormones, neurotransmitters, and drugs.

13 Feb 2026

Ozempic users continue treatment when weight loss works despite side effects

A study on Ozempic for weight loss reveals user satisfaction is driven by efficacy, despite common gastrointestinal side effects impacting treatment adherence.

13 Feb 2026

New research initiative examines impact of legal psychedelic services in community settings

A federally funded research initiative will enable researchers at Oregon Health & Science University and other organizations to assess the safety and effectiveness of state-regulated access to psilocybin, also known as magic mushrooms.

12 Feb 2026

Study examines the relationship between leukocyte telomere length and age-related cataract

Cataracts remain the leading cause of blindness worldwide among adults over 50, despite major advances in surgical treatment.

12 Feb 2026

Switching lens designs may enhance long-term myopia control

Myopia has become a major global public health concern, with rising prevalence and earlier onset among children worldwide.

12 Feb 2026

Light-based sensor can detect low concentrations of cancer biomarkers in the blood

Researchers have developed a highly sensitive light-based sensor that can detect extremely low concentrations of cancer biomarkers in the blood.

12 Feb 2026

SLAMF6 discovery offers hope for non-responding cancer patients

Cancer researchers working on immunotherapies have made a big discovery: SLAMF6, a molecule on the surface of immune cells that prevents T cells from effectively attacking tumors – and, in mice, they've found a way to neutralize it.

12 Feb 2026

Nanovaccine design boosts immune attack on HPV tumors

Throughout the past decade, Northwestern University scientists have uncovered a striking principle of vaccine design: Performance depends not only on vaccine components but also on vaccine structure.

11 Feb 2026

Trial highlights promising frontline therapy for blastic plasmacytoid dendritic cell neoplasm

Seventy-five percent of patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN) who were treated with the antibody-drug conjugate (ADC) pivekimab sunirine (PVEK) had a complete response, according to new data from the Phase I/II multicenter international CADENZA trial led by researchers at The University of Texas MD Anderson Cancer Center.

11 Feb 2026

Nurses provide hospital care as safely as doctors

Nurses can safely deliver many services traditionally performed by doctors, with little to no difference in deaths, safety events, or how patients felt about their health, according to a new Cochrane review.

11 Feb 2026

Alzheimer’s plaques decline after CAR-T immune cell treatment in preclinical study

Researchers engineered CD4+ chimeric antigen receptor T cells targeting fibrillar amyloid beta and tested them in a mouse Alzheimer model. The preclinical study showed reduced amyloid pathology and altered neuroimmune responses, supporting CAR-T immunotherapy as a potential future Alzheimer strategy.

11 Feb 2026

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Efficacy News and Research

Does intermittent fasting help you lose more weight? Evidence review finds no clear advantage

Myopia may be driven by prolonged close-up focus in low-light environments

Chronic inflammation shapes cancer progression and immunotherapy response

OVACell project pioneers viral target immunotherapy for ovarian cancer

Nasal COVID vaccine boost increases IgA responses linked to variant neutralisation

Vitamin A and thyroid hormones in the retina shape fetal vision

Review compares surgical and neurostimulation outcomes in temporal lobe epilepsy

Engineered Listeria boosts innate immunity against cancer

Diacerein shows promise as disease-modifying therapy in rheumatoid arthritis

Thermodynamic insights into histamine H1 receptor ligand binding

Ozempic users continue treatment when weight loss works despite side effects

New research initiative examines impact of legal psychedelic services in community settings

Study examines the relationship between leukocyte telomere length and age-related cataract

Switching lens designs may enhance long-term myopia control

Light-based sensor can detect low concentrations of cancer biomarkers in the blood

SLAMF6 discovery offers hope for non-responding cancer patients

Nanovaccine design boosts immune attack on HPV tumors

Trial highlights promising frontline therapy for blastic plasmacytoid dendritic cell neoplasm

Nurses provide hospital care as safely as doctors

Alzheimer’s plaques decline after CAR-T immune cell treatment in preclinical study

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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