Gene Editing News and Research

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New microcapsules represent promising vectors for application of genome-editing tools

Researchers from Tomsk Polytechnic University jointly with their colleagues from St. Petersburg, Hamburg and London have conducted a study in the course of which it was found out that polymer and hybrid silica-coated microcapsules are more efficient in genome-editing when applying CRISPR-Cas9 system.

6 Oct 2017

CGT Catapult’s iPSC line licensed to Universal Cells for creating universal donor cell line

The Cell and Gene Therapy Catapult today announced a non-exclusive licensing agreement to provide its clinical-grade induced Pluripotent Stem Cell line to Seattle based Universal Cells.

6 Oct 2017

CRISPR-Gold corrects gene mutations in mice with Duchenne muscular dystrophy

Scientists at the University of California, Berkeley, have engineered a new way to deliver CRISPR-Cas9 gene-editing technology inside cells and have demonstrated in mice that the technology can repair the mutation that causes Duchenne muscular dystrophy, a severe muscle-wasting disease.

4 Oct 2017

Gene editing technique helps uncover potential new drug targets for KRAS-driven cancers

Cancers driven by mutations in the KRAS gene are among the most deadly. For decades, researchers have tried unsuccessfully to directly target mutant KRAS proteins as a means to treat tumors.

28 Sep 2017

Understanding molecular mechanisms and metabolic pathways of yeast for drug discovery

My research uses budding yeast as a tool for synthetic biology, and also in chemical and functional genomic applications. We are interested in understanding molecular mechanisms and metabolic pathways of yeast for drug discovery.

From Tecan 27 Sep 2017

Scientists use genome editing to understand role of a gene key to human embryonic development

Researchers have used a genome-editing technique to elucidate the role of a gene that is key to human embryonic development.

21 Sep 2017

Research could lead to improvements in treating diseases caused by mutations in genes

Research carried out by academics at Northumbria University, Newcastle could lead to improvements in treating patients with diseases caused by mutations in genes, such as cancer, cystic fibrosis and potentially up to 6,000 other inherited conditions.

19 Sep 2017

New human stem cell model could pave way for macular degeneration research

Macular degeneration is the leading cause of vision loss in older adults, but scientists have long struggled to study and replicate key elements of the disease in the lab.

7 Sep 2017

Scientists question CRISPR human embryo editing claims

A paper published in the journal Nature on the 2nd August described how a gene editing tool CRISPR could be used to correct a genetic mutation that leads to a heart condition. This team had performed the genetic editing on the gene sequences in dozens of viable human embryos to attempt to prevent a genetic heart condition called hypertrophic cardiomyopathy.

31 Aug 2017

New biomedical tool using nanoparticles could improve therapies for many diseases

A new biomedical tool using nanoparticles that deliver transient gene changes to targeted cells could make therapies for a variety of diseases -; including cancer, diabetes and HIV -; faster and cheaper to develop, and more customizable.

30 Aug 2017

Id genes found to play crucial role in heart development

Researchers from Sanford Burnham Prebys Medical Discovery Institute (SBP), the Cardiovascular Institute at Stanford University and other institutions were surprised to discover that the four genes in the Id family play a crucial role in heart development, telling undifferentiated stem cells to form heart tubes and eventually muscle.

22 Aug 2017

GM pigs one step closer to providing organs for human transplant

US scientists are the closest yet to creating genetically modified pigs with organs that can be safely transplanted into humans.

14 Aug 2017

New version of gene editing technique corrects molecular mistakes in RNA-based diseases

Until recently, the CRISPR-Cas9 gene editing technique could only be used to manipulate DNA. In a 2016 study, University of California San Diego School of Medicine researchers repurposed the technique to track RNA in live cells in a method called RNA-targeting Cas9 (RCas9).

11 Aug 2017

Genome editing – public perceptions studied

Genome editing is fast becoming a norm with more and more research teams working on this arena and coming up with new cutting edge developments. However attitudes towards genetic modifications vary with several opinions – political, moral and religious, raising concerns.

11 Aug 2017

Xenotransplantation – organ transplants from animals may soon be a reality

Researchers have been able to create genetically modified piglets that are cleaned of the viruses that could causes diseases in humans. This could open up new avenues in organs transplants from pigs to humans. The process of transplanting organs or tissues from animals to humans is called xenotransplantation. The report was published this Tuesday in the journal Science.

11 Aug 2017

Study shows new method for repairing disease-causing mutation in human embryos

Scientists have demonstrated an effective way of using a gene-editing tool to correct a disease-causing gene mutation in human embryos and stop it from passing to future generations.

3 Aug 2017

Research shows great potential of embryonic gene editing to prevent inherited diseases

Scientists have, for the first time, corrected a disease-causing mutation in early stage human embryos with gene editing.

2 Aug 2017

Expert highlights CRISPR’s applications, limitations, and ethical concerns

"Good morning, doctor, I am here for my gene editing appointment." In the future, could this be a greeting heard in physician offices around the world? With the introduction of CRISPR technology, genetic material can now be more easily and precisely edited, even creating changes that can subsequently be inherited by offspring.

1 Aug 2017

Mathematical modeling can guide design and distribution of genetically modified genes

So, you've genetically engineered a malaria-resistant mosquito, now what? How many mosquitos would you need to replace the disease-carrying wild type? What is the most effective distribution pattern? How could you stop a premature release of the engineered mosquitos?

1 Aug 2017

Bringing highly potent cell therapy products to market

There are two main challenges and both relate to manufacturing. The first one is to make sure you can manufacture therapies with reasonable costs and the second one is to make sure that you can balance the capacity you need with the demands.

31 Jul 2017

Gene Editing News and Research

New microcapsules represent promising vectors for application of genome-editing tools

CGT Catapult’s iPSC line licensed to Universal Cells for creating universal donor cell line

CRISPR-Gold corrects gene mutations in mice with Duchenne muscular dystrophy

Gene editing technique helps uncover potential new drug targets for KRAS-driven cancers

Understanding molecular mechanisms and metabolic pathways of yeast for drug discovery

Scientists use genome editing to understand role of a gene key to human embryonic development

Research could lead to improvements in treating diseases caused by mutations in genes

New human stem cell model could pave way for macular degeneration research

Scientists question CRISPR human embryo editing claims

New biomedical tool using nanoparticles could improve therapies for many diseases

Id genes found to play crucial role in heart development

GM pigs one step closer to providing organs for human transplant

New version of gene editing technique corrects molecular mistakes in RNA-based diseases

Genome editing – public perceptions studied

Xenotransplantation – organ transplants from animals may soon be a reality

Study shows new method for repairing disease-causing mutation in human embryos

Research shows great potential of embryonic gene editing to prevent inherited diseases

Expert highlights CRISPR’s applications, limitations, and ethical concerns

Mathematical modeling can guide design and distribution of genetically modified genes

Bringing highly potent cell therapy products to market

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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