Metabolite News and Research

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Metabolites are the intermediates and products of metabolism. The term ''metabolite'' is usually restricted to small molecules.

Caffeine metabolite could become a valuable treatment for myopia in children

A metabolite of caffeine, known as 7-MX, may slow the progression of short-sightedness, also known as myopia, in children, suggests observational research published online in the British Journal of Ophthalmology.

23 Aug 2022

New treatment may help counteract food allergies and inflammatory diseases in future

Although many people with dietary allergies experience mild symptoms when exposed to triggering foods, some face potentially fatal consequences.

22 Aug 2022

Intestinal tissue-resident lymphocytes regulate their activity depending on glucose availability

A new study led by Marc Veldhoen, group leader at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal) and Associate Professor at Faculdade de Medicina de Lisboa (FMUL) and published today in the scientific journal PNAS (Proceedings of the National Academy of Sciences of the United States of America) discovered that white blood cells that reside in the intestines, a specific group of immune cells called tissue-resident lymphocytes, use sugar as an energy source and have a faster metabolism than lymphocytes that circulate in the blood.

15 Aug 2022

What is the association between polyfluoroalkyl substance exposure and risk of non-viral hepatocellular carcinoma?

The current study, published online in the journal JHEP Reports, looks at PFAS, which are endocrine disruptors and potential hepatotoxins.

11 Aug 2022

The effects of CBD in the treatment of COVID-19–related inflammatory symptoms

Researchers reviewed the effectiveness of cannabidiol in treating COVID-19 inflammatory-related symptoms.

28 Jul 2022

Genetic variations in one serotonin receptor could be the reason behind psychedelic treatment disparity

When all else fails, some patients trying to overcome alcoholism, severe depression or anxiety, and even cluster headaches, turn to psychedelic drugs, which clinical research has shown can help treat individuals with these conditions, sometimes with dramatically positive results.

27 Jul 2022

Genome arrangement of tree ferns offers insights into its evolution

Land plants evolved 470 million years ago from algae and have since reshaped our world. Throughout their evolution, ferns have undergone a series of changes that have helped them survive on land.

25 Jul 2022

Scientists develop an improved pharmaceutical drug for the treatment of atrial fibrillation

Scientists from the National University of Singapore Department of Pharmacy have developed an improved pharmaceutical drug for the treatment of the most common heart rhythm disturbance – atrial fibrillation (AF).

18 Jul 2022

Nitazoxanide drug found to be a potent inhibitor of several human coronaviruses

Researchers evaluated the activity of nitazoxanide against human coronaviruses (HCoVs).

18 Jul 2022

Evidence for a specific anti-inflammatory metabolic signature in long-COVID

A recent research paper posted to the medRxiv* preprint server illustrated anti-inflammatory and hypo-metabolic fingerprints in long coronavirus disease (COVID) syndrome (LCS) using pan-omics plasma assessments.

15 Jul 2022

Lipids in breastmilk may protect against metabolic disease later in life

A new study examines the lipid content in breastmilk and its association with NCDs later in life.

13 Jul 2022

Exposure to multiple phthalates during pregnancy increases risk of preterm birth

Pregnant women who were exposed to multiple phthalates during pregnancy had an increased risk of preterm birth, according to new research by the National Institutes of Health.

11 Jul 2022

Characterization of longer-term effects on behavior and brain inflammation following recovery from mild COVID-19

A recent study reported that long COVID in mice causes brain inflammation and cognitive impairment.

8 Jul 2022

New computer model can accurately predict the communities formed by human gut microbes

The communities formed by human gut microbes can now be predicted more accurately with a new computer model developed in a collaboration between biologists and engineers, led by the University of Michigan and the University of Wisconsin.

7 Jul 2022

A Spanish study found traces of environmental pollution in breast milk

A new study reveals that breast milk is often contaminated by environmental pollutants.

6 Jul 2022

New discovery could lead to more effective treatments for asthma sufferers

New research led by Edith Cowan University has made an important discovery that could lead to more effective treatments for the world's 262 million asthma sufferers.

4 Jul 2022

The antiviral effects of thiol drugs in COVID-19

A recent study investigated the effects of thiol drugs on SARS-CoV-2.

1 Jul 2022

Mother's gut microbes can aid in the healthy development of baby, finds study

Researchers studying mice have found the first evidence of how a mother's gut microbes can help in the development of the placenta, and the healthy growth of the baby.

28 Jun 2022

Vitamin D supplements show promise to counter the adverse effects of diabetes drug on bone health

Vitamin D supplementation may help offset damaging bone loss that occurs in some people who take canagliflozin, a commonly prescribed diabetes drug.

27 Jun 2022

Mild COVID causes increase in neurotoxic metabolites

In a recent study posted to the bioRxiv* pre-print server, researchers investigated the blood levels of neurotoxic metabolites in patients with mild coronavirus disease 2019 (COVID-19).

23 Jun 2022