Efficacy News and Research

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30-year-old cancer drug could get another shot, study says

A study by Virginia Commonwealth University Massey Cancer Center researchers published in today's print edition of Molecular Cancer Therapeutics shows that triplatin is effective against triple negative breast cancer, which is the most aggressive form of breast cancer and has few targeted therapies.

9 Feb 2022

Swedish study shows fully vaccinated are protected against severe COVID-19

Researchers evaluate the risk of severe Omicron infections in several risk categories defined by sex, age, comorbidities, and vaccination status.

8 Feb 2022

Impact of SARS-CoV-2 Omicron and Delta variants on serious hospital events

In a new study, a team of researchers assessed the differences in risk of hospitalization in adults after infection with SARS-CoV-2 Omicron and Delta variants.

8 Feb 2022

Comparison of school protocols under the high incidence conditions due to the Omicron variant

The current study discusses the proactive vs. reactive school protocols relative to the peak demands for resources, break in infection, and the number of days of school lost.

8 Feb 2022

Reanalysis of the efficacy of COVID-19 vaccines

In a new study, researchers investigated the impact of trial study design and other parameters on the estimates of COVID-19 vaccine efficacy.

8 Feb 2022

Study identifies lower viral load in the nasopharyngeal samples of patients infected with SARS-CoV-2 Omicron variant

In a new study, researchers determined if the higher transmission rate of the SARS-CoV-2 Omicron variant is due to a higher viral load compared to the Delta variant.

8 Feb 2022

Efficacy of MVA-CoV2-S vaccination to prevent SARS-CoV-2 cerebral infection and associated damage

Researchers demonstrated that an MVA vector expressing the SARS-CoV-2 spike protein was 100% effective in preventing neuroinvasion and brain damage by SARS-CoV-2 in transgenic mice.

8 Feb 2022

Culinary medicine curriculum has a positive impact on outcomes for patients with type 2 diabetes

A culinary medicine curriculum had a positive impact on certain biometric and diet-related behavioral and psychosocial outcomes among low-income, food-insecure patients with type 2 diabetes participating in a clinic-led food prescription program, according to researchers with The University of Texas Health Science Center at Houston.

8 Feb 2022

SARS-CoV-2 cytokine storm inhibited by curcumin nanoparticles

In a recent study published in the journal ACS Applied Bio Materials, researchers demonstrated the inhibitory potential of curcumin-encapsulated polysaccharide nanoparticles (CUR−PS-NPs) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (CoV2-SP)-stimulated cytokine storm in lung and liver epithelial cells.

8 Feb 2022

Investigating taraxerol as a protease inhibitor against SARS-CoV-2

In a recent study posted to the Research Square preprint* server, a team of researchers investigated the toxicity and absorption, distribution, metabolism, and excretion (ADME) characteristics of a potent herbal drug, taraxerol, in the management of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The paper is under consideration for publication in the Structural Chemistry journal.

7 Feb 2022

SARS-CoV-2 Delta variant's effect on COVID-19 vaccine efficacy

In a recent research paper published in the journal Infection, the scientists estimated the transmission and disease severity associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant and the effectiveness of the current coronavirus disease 2019 (COVID-19) vaccines against the same by conducting a literature review. Further, a meta-analysis was conducted to obtain a numeric estimate of the vaccine effectiveness against the Delta variant.

7 Feb 2022

mRNA-based COVID-19 booster vaccination shown to protect against severe omicron infection in macaques

Scientists recently evaluated the effectiveness of a booster dose of the Moderna-developed COVID-19 vaccine and omicron spike-specific mRNA vaccine in non-human primates that are primed with the Moderna vaccine.

7 Feb 2022

Study explores omicron-reactive T- and B- cell responses in COVID-19 vaccine recipients

A new study analyzes neutralizing antibodies and T-cell responses targeting the SARS-CoV-2 D614G, as well as some variants of concern.

7 Feb 2022

Evaluating delayed vaccination schedules for protection against SARS-CoV-2

Researchers conducted an observational study to compare the humoral and cellular responses in health care workers who had received two doses of the Pfizer-BioNTech vaccine at standard (3 to 6 weeks) and delayed (8 to 16 week) intervals.

7 Feb 2022

Northwestern researchers study COVID-19 mechanisms, infection patterns and impact on gender minorities

Northwestern Medicine investigators continue to study the COVID-19 pandemic, from the biological mechanisms of disease and infection patterns to the pandemic's impact on women and sexual and gender minorities.

6 Feb 2022

Researchers discover a new function of anti-HIV-1 antibodies

Teams at the Institut Pasteur, CNRS, Vaccine Research Institute (VRI) and Université de Paris have discovered a new function of anti-HIV-1 antibodies by applying cutting-edge microscopy techniques to in vitro viral cultures.

6 Feb 2022

A novel approach to predict mutations within the SARS-CoV-2 spike

A study posted recently to the bioRxiv* preprint server demonstrated that the emergence of new spike variants of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) can be predicted.

6 Feb 2022

AI systems may one day assist anesthesiologists in the operating room, study suggests

A new study by researchers at MIT and Massachusetts General Hospital suggests the day may be approaching when advanced artificial intelligence systems could assist anesthesiologists in the operating room.

6 Feb 2022

Greater neutralizing titers observed in vaccinated individuals with breakthrough Omicron infection

Researchers assess the neutralizing power of plasma samples collected from Omicron convalescent individuals who were either vaccinated or unvaccinated.

6 Feb 2022

mRNA booster vaccination shown to induce robust neutralizing antibodies against SARS-CoV-2 omicron variant

Scientists recently assessed the immunogenicity of a third booster dose of COVID-19 vaccines against SARS-CoV-2 variants.

4 Feb 2022

Efficacy News and Research

30-year-old cancer drug could get another shot, study says

Swedish study shows fully vaccinated are protected against severe COVID-19

Impact of SARS-CoV-2 Omicron and Delta variants on serious hospital events

Comparison of school protocols under the high incidence conditions due to the Omicron variant

Reanalysis of the efficacy of COVID-19 vaccines

Study identifies lower viral load in the nasopharyngeal samples of patients infected with SARS-CoV-2 Omicron variant

Efficacy of MVA-CoV2-S vaccination to prevent SARS-CoV-2 cerebral infection and associated damage

Culinary medicine curriculum has a positive impact on outcomes for patients with type 2 diabetes

SARS-CoV-2 cytokine storm inhibited by curcumin nanoparticles

Investigating taraxerol as a protease inhibitor against SARS-CoV-2

SARS-CoV-2 Delta variant's effect on COVID-19 vaccine efficacy

mRNA-based COVID-19 booster vaccination shown to protect against severe omicron infection in macaques

Study explores omicron-reactive T- and B- cell responses in COVID-19 vaccine recipients

Evaluating delayed vaccination schedules for protection against SARS-CoV-2

Northwestern researchers study COVID-19 mechanisms, infection patterns and impact on gender minorities

Researchers discover a new function of anti-HIV-1 antibodies

A novel approach to predict mutations within the SARS-CoV-2 spike

AI systems may one day assist anesthesiologists in the operating room, study suggests

Greater neutralizing titers observed in vaccinated individuals with breakthrough Omicron infection

mRNA booster vaccination shown to induce robust neutralizing antibodies against SARS-CoV-2 omicron variant

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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