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Researchers unravel path of metallodrug in a breast cancer cell

Some types of cancer cannot be treated with classical chemotherapy. Scientists from Inserm, CNRS, Sorbonne University, PSL university, University Grenoble Alpes and ESRF, the European Synchrotron, are working on a metallorganic molecule as an antitumor drug.

4 Feb 2019

Iridium attached to albumin can attack cancer cells when blasted with light

A new compound based on Iridium, a rare metal which landed in the Gulf of Mexico 66 M years ago, hooked onto albumin, a protein in blood, can attack the nucleus of cancerous cells when switched on by light, University of Warwick researchers have found.

4 Feb 2019

New research uncovers crucial link between polyamines and MYCN

The MYCN oncogene has long been known to be a key cause of a number of deadly solid tumor cancers, including neuroblastoma, which claims more lives of children under the age of 5 than any other cancer.

4 Feb 2019

Research could potentially lead to new treatments for neurodegenerative diseases

Scientists from the University of Sheffield have identified new messenger molecules shuttled between cells which could help to protect the survival of neurones - potentially leading to new treatments for MND .

1 Feb 2019

New method predicts how drug molecules arrange themselves under changing energetic conditions

One major factor that determines the efficacy of a drug is the structure that its molecules form in a solid state.

1 Feb 2019

Researchers use mouse models to explain the developmental process behind COPD

The airways and lungs are affected by a range of diseases, but while some have been well characterized and treated, others such as chronic obstructive pulmonary disorder (COPD) are still somewhat of an enigma.

1 Feb 2019

Lab model reveals the formation of new blood vessels

To provide sufficient oxygen to tissues and organs within the body, blood vessels need to sprout new offshoots to form a widespread blood supply network, much like the trunk, branches, and twigs of a tree.

31 Jan 2019

Expediting HPLC Method Development in Pharmaceutical Analysis

In this interview, Michael Dong discusses stability-indicating methods such as UHPLC, in pharmaceutical analysis. At Pittcon, Michael will introduce a 3-pronged template approach to HPLC method development.

From Pittcon 30 Jan 2019

Researchers discover how transcription factors find specific loci within DNA

Bioengineering experts have discovered that transcription factors which bind non-specifically to mitotic chromosomes are more efficient at finding their binding site within DNA during interphase.

30 Jan 2019

Metrion collaborates with LifeArc on neuroscience-focused ion channel drug discovery project

Metrion Biosciences and LifeArc have entered into a collaboration agreement for an ion channel drug discovery project in the field of neuroscience.

From Metrion Biosciences Limited 30 Jan 2019

New insight into anti-malaria drug

Artemisinin is derived from the leaves and flowers of the annual mugwort (Artemisia annua) and has been used in traditional Chinese medicine for centuries. The effectiveness was investigated by the Chinese researcher Tu Youyou.

29 Jan 2019

New study elucidates role of signaling molecule in development of myocarditis

Researchers of Ludwig-Maximilians-Universitaet in Munich have shown that a protein called midkine, a member of the class of signaling molecules known as cytokines, is a key driver of inflammation in the heart muscle that can lead to heart failure in patients with myocarditis.

29 Jan 2019

Two major forms of CD44 have distinct biological functions in breast cancer, shows study

One of the main obstacles to successfully treating breast cancer is the cells' ability to change in ways that make them resistant to treatment.

29 Jan 2019

Stand Up To Cancer creates Dream Team focused on finding therapies for T-cell lymphoma

Stand Up To Cancer announced here today the creation of an $8 million Dream Team of top scientists focused on finding therapies for T-cell lymphoma, a rare cancer of the blood and immune system, using chimeric antigen receptors (CARs) to trigger the immune system to attack and destroy cancerous cells.

29 Jan 2019

Researchers identify why heart attack triggers arrhythmia in some people

A team of researchers led by the University of California San Diego has identified a genetic pathway that causes some individuals to develop an abnormal heart rhythm, or arrhythmia, after experiencing a heart attack. They have also identified a drug candidate that can block this pathway.

29 Jan 2019

New study may help develop corrective mechanisms for neurodegenerative diseases, ischemia

In the last decade, there has been a growing body of experimental data confirming that neural networks are the minimal functional unit of the nervous system.In the last decade, there has been a growing body of experimental data confirming that neural networks are the minimal functional unit of the nervous system.

29 Jan 2019

Researchers create synthetic growth factor that offers comparable biological response

Growth factors are ligands that play important roles in the body - they are responsible for tissue regeneration, wound healing, and the maintenance and growth of cells.

28 Jan 2019

Regular use of aspirin may help some patients survive head and neck cancer

Regular use of aspirin or other nonsteroidal anti-inflammatory drugs may help some patients with head and neck cancer survive the disease, according to a study led by Professor Jennifer Grandis at the University of California, San Francisco.

27 Jan 2019

Regular use of common pain relief medicines improves survival for head and neck cancer patients

Regular use of a common type of medication, such as aspirin and ibuprofen, significantly improves survival for a third or more patients with head and neck cancer, a new study led by UC San Francisco has found.

25 Jan 2019

Study uncovers new link between inflammation and cancer

Severe inflammation in tissues is often associated with the occurrence of cancer. The mechanism linking both these conditions is not clearly understood. Furthermore, inflamed and cancerous tissues contain a heterogenous mix of damaged and protective cells.

24 Jan 2019

Molecule News and Research

Researchers unravel path of metallodrug in a breast cancer cell

Iridium attached to albumin can attack cancer cells when blasted with light

New research uncovers crucial link between polyamines and MYCN

Research could potentially lead to new treatments for neurodegenerative diseases

New method predicts how drug molecules arrange themselves under changing energetic conditions

Researchers use mouse models to explain the developmental process behind COPD

Lab model reveals the formation of new blood vessels

Expediting HPLC Method Development in Pharmaceutical Analysis

Researchers discover how transcription factors find specific loci within DNA

Metrion collaborates with LifeArc on neuroscience-focused ion channel drug discovery project

New insight into anti-malaria drug

New study elucidates role of signaling molecule in development of myocarditis

Two major forms of CD44 have distinct biological functions in breast cancer, shows study

Stand Up To Cancer creates Dream Team focused on finding therapies for T-cell lymphoma

Researchers identify why heart attack triggers arrhythmia in some people

New study may help develop corrective mechanisms for neurodegenerative diseases, ischemia

Researchers create synthetic growth factor that offers comparable biological response

Regular use of aspirin may help some patients survive head and neck cancer

Regular use of common pain relief medicines improves survival for head and neck cancer patients

Study uncovers new link between inflammation and cancer

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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