Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Research roundup: Hospital readmissions; researchers mistrust social media; premiums in Washington state

Reducing hospital readmissions is a major target for current quality improvement and cost-containment efforts.

16 Jun 2014

Researchers examine why tubulin acetyltransferase is important for brain health

In a new study, scientists at the National Institutes of Health took a molecular-level journey into microtubules, the hollow cylinders inside brain cells that act as skeletons and internal highways.

16 Jun 2014

Researchers develop rapid-acting antidepressants for treatment-resistant depression

UT Southwestern Medical Center researchers have generated fresh insights that could aid in the development of rapid-acting antidepressants for treatment-resistant depression.

13 Jun 2014

High-protein diets lower stroke risk

People with diets higher in protein, especially from fish, may be less likely to have a stroke than those with diets lower in protein, according to a meta-analysis published in the June 11, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology.

12 Jun 2014

REM sleep disorder: A sign of impending neurodegenerative disease

How many millions of people suffer from sleep disturbance? One sleep disorder in particular, called REM behavior disorder, could be a sign of impending neurodegenerative disease, including Parkinson's and dementia, say scientists presenting their research at the Society of Nuclear Medicine and Molecular Imaging's 2014 Annual Meeting.

10 Jun 2014

Late-life depression could become major risk factor for developing Alzheimer's

Many people develop depression in the latest stages of life, but until now doctors had no idea that it could point to a build up of a naturally occurring protein in the brain called beta-amyloid, a hallmark of Alzheimer's disease.

10 Jun 2014

National Institutes of Health awards $3.4M grant for Alzheimer's disease research

As part of its ongoing research to better understand the complexities of the human brain, the Allen Institute for Brain Science is embarking on the first effort to map connectivity patterns across the whole brain in mouse models of Alzheimer's disease, through its recent award of a $3.4 million grant over five years from the National Institute on Aging of the National Institutes of Health.

9 Jun 2014

New mathematical models seem to explain processing in medial temporal lobes

When it comes to familiarity, a slew of memories including seemingly unrelated ones can come flooding into the brain, according to mathematical theories called global similarity models.

9 Jun 2014

Study: The brain controls cellular process that leads to glaucoma

Findings from a new study published in Translational Vision Science & Technology show the brain, not the eye, controls the cellular process that leads to glaucoma. The results may help develop treatments for one of the world's leading causes of irreversible blindness, as well as contribute to the development of future therapies for preserving brain function in other age-related disorders like Alzheimer's.

6 Jun 2014

Novel diagnostic tool helps differentiate between dementia diseases

A new diagnostic tool helps clinicians to differentiate between Alzheimer's disease, frontotemporal dementia and mild cognitive impairment. Presented in the doctoral thesis of MD Miguel ángel Muñoz Ruiz at the University of Eastern Finland, the new method consists of a Disease State Index combining data from multiple sources, and of a Disease State Fingerprint showing the findings in a visual format.

5 Jun 2014

Variety of lifestyle and health factors increase memory complaints among young adults

If you're depressed, don't get enough exercise or have high blood pressure, you may find yourself complaining more about memory problems, even if you're a young adult, according to a new UCLA study.

5 Jun 2014

Researchers examine how high blood pressure in middle age affects memory and thinking in old age

New research suggests that high blood pressure in middle age plays a critical role in whether blood pressure in old age may affect memory and thinking.

5 Jun 2014

Tailored light treatment can improve sleep and behavior in people with Alzheimer's disease

A new study suggests that light treatment tailored to increase circadian stimulation during the day may improve sleep, depression and agitation in people with Alzheimer's disease and related dementia.

5 Jun 2014

New gene involved in Parkinson's disease, find researchers

A team of UCLA researchers has identified a new gene involved in Parkinson's disease, a finding that may one day provide a target for a new drug to prevent and potentially even cure the debilitating neurological disorder.

5 Jun 2014

Synthetic peptide carrier delivers drugs through blood-brain barrier for cancer treatment

Researchers at Mayo Clinic have demonstrated in a mouse model that their recently developed synthetic peptide carrier is a potential delivery vehicle for brain cancer chemotherapy drugs and other neurological medications. The findings appear in PLOS ONE.

4 Jun 2014

UAB launches personalized dementia risk assessment clinic

Neurologist David Geldmacher, M.D., who leads the University of Alabama at Birmingham memory disorders program, sees a lot of older patients with memory loss, dementia or Alzheimer's disease.

4 Jun 2014

AFFiRiS releases positive study results of AD04 therapeutic drug in Alzheimer patients

AFFiRiS announced today the results of a phase II study in Alzheimer patients. AFFiRiS' proprietary compound AD04 is the first drug ever to demonstrate clinical and biomarker effects consistent with disease modification in Alzheimer patients.

4 Jun 2014

Scientists design search engine to identify functionally linked genes

Our bodies are as vast as oceans and space, composed of a dizzying number of different types of cells. Exploration reaches far, yet the genes that make each cell and tissue unique have remained largely obscure.

4 Jun 2014

NYU Langone scientists identify promising treatment target for Alzheimer's disease

Scientists at NYU Langone Medical Center have identified a compound, called 2-PMAP, in animal studies that reduced by more than half levels of amyloid proteins in the brain associated with Alzheimer's disease.

3 Jun 2014

Study warns against use of resveratrol supplements by pregnant women

A widely available dietary supplement that had been considered safe - and that some claim provides anti-aging and other health benefits - caused significant developmental abnormalities in the pancreas of offspring of pregnant monkeys who were given the supplement, according to a study published today in the FASEB Journal, from the Federation of American Societies of Experimental Biology.

3 Jun 2014

Alzheimer's Disease News and Research

Further Reading

Research roundup: Hospital readmissions; researchers mistrust social media; premiums in Washington state

Researchers examine why tubulin acetyltransferase is important for brain health

Researchers develop rapid-acting antidepressants for treatment-resistant depression

High-protein diets lower stroke risk

REM sleep disorder: A sign of impending neurodegenerative disease

Late-life depression could become major risk factor for developing Alzheimer's

National Institutes of Health awards $3.4M grant for Alzheimer's disease research

New mathematical models seem to explain processing in medial temporal lobes

Study: The brain controls cellular process that leads to glaucoma

Novel diagnostic tool helps differentiate between dementia diseases

Variety of lifestyle and health factors increase memory complaints among young adults

Researchers examine how high blood pressure in middle age affects memory and thinking in old age

Tailored light treatment can improve sleep and behavior in people with Alzheimer's disease

New gene involved in Parkinson's disease, find researchers

Synthetic peptide carrier delivers drugs through blood-brain barrier for cancer treatment

UAB launches personalized dementia risk assessment clinic

AFFiRiS releases positive study results of AD04 therapeutic drug in Alzheimer patients

Scientists design search engine to identify functionally linked genes

NYU Langone scientists identify promising treatment target for Alzheimer's disease

Study warns against use of resveratrol supplements by pregnant women

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