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Researchers discover Ebola-fighting protein in human cells

Researchers have discovered a human protein that helps fight the Ebola virus and could one day lead to an effective therapy against the deadly disease, according to a new Northwestern Medicine study.

13 Dec 2018

Advanced spectroscopic techniques used to prepare, characterize major degradation products of pralatrexate injection

The major degradation products of pralatrexate drug product formed under hydrolytic and light stress conditions were identified, synthesized, and characterized using advanced spectroscopic techniques such as NMR, HR-MS, and IR.

13 Dec 2018

New method to visualize small-molecule interactions inside cells

Like people in a large company, proteins in cells constantly interact with each other to perform various jobs. To develop new disease therapies, researchers are trying to control these interactions with small-molecule drugs that cause specific proteins to associate more or less with their "coworkers."

13 Dec 2018

New mouse model shows potential for rapid identification of promising muscular dystrophy therapies

A Massachusetts General Hospital research team has created a new mouse model of a common form of muscular dystrophy with the potential of rapidly distinguishing promising therapeutic drugs from those unlikely to be successful.

13 Dec 2018

Unraveling the complexity of cancer biology can prompt new avenues for drug development

Unraveling the complexity of cancer biology can lead to the identification of new molecules involved in breast cancer and prompt new avenues for drug development. And proteogenomics, an integrated, multipronged approach, seems to be a way to do it.

13 Dec 2018

Researchers use INTEGRA's VIAFLO 96/384 to streamline the experimental workflow

Researchers are using INTEGRA’s VIAFLO 96/384 multichannel electronic pipette to study Pseudomonas aeruginosa.

From INTEGRA Biosciences 12 Dec 2018

IONTAS founder and pioneer in phage display technology attends Nobel Prize Award Ceremony

Dr. John McCafferty celebrates the success of phage display technology with Nobel Prize in Chemistry Laureates.

From FairJourney Biologics 12 Dec 2018

Targeting biochemical pathway may lead to new therapies for alleviating symptoms of anxiety disorders

According to some estimates, up to one in three people around the world may experience severe anxiety in their lifetime.

12 Dec 2018

Single tau molecule holds clues to help diagnose neurodegeneration in its earliest stages

Scientists who recently identified the molecular start of Alzheimer's disease have used that finding to determine that it should be possible to forecast which type of dementia will develop over time - a form of personalized medicine for neurodegenerative diseases.

11 Dec 2018

Brazilian professors propose guidelines for therapeutic use of melatonin

Sixty years after melatonin was isolated and with more than 23,000 published studies showing the many functions of this hormone secreted by the pineal gland, guidelines should be discussed and established for its therapeutic use.

11 Dec 2018

Deadly combination: Drug cocktail induces cancer cell death by switching off energy supply

A widely used diabetes medication combined with an antihypertensive drug specifically inhibits tumor growth - this was discovered by researchers from the University of Basel's Biozentrum two years ago. In a follow-up study, recently published in Cell Reports, the scientists report that this drug cocktail induces cancer cell death by switching off their energy supply.

11 Dec 2018

ESMO Immuno-Oncology Congress showcases novel technologies set to benefit many cancer patients

Innovation in immuno-oncology is exploding and new technologies that are set to benefit many patients with cancer are being showcased in the highly diverse array of topics to be discussed at the ESMO Immuno-Oncology Congress, to be held 13-16 December in Geneva, Switzerland.

11 Dec 2018

Research findings could lead to new targets for cancer-fighting therapeutics

A molecular pathway that's frequently mutated in many different forms of cancer becomes active when cells push parts of their membranes outward into bulging protrusions, Johns Hopkins researchers report in a new study.

11 Dec 2018

Researchers identify potential diagnostic tool for Alzheimer’s disease

Researchers at Johns Hopkins Medicine have identified in live human brains new radioactive “tracer” molecules that bind to and “light up” tau tangles, a protein associated with a number of neurodegenerative diseases including Alzheimer’s disease and other related dementias.

11 Dec 2018

Researchers shed new light on how to combat Shiga and ricin toxins

Min Dong, PhD, and his lab are world experts in toxins and how to combat them. They've figured out how Clostridium difficile's most potent toxin gets into cells and zeroed in on the first new botulinum toxin identified since 1969.

11 Dec 2018

Researchers capture high-resolution X-ray and NMR image of key immune regulator

A new study by investigators from Brigham and Women's Hospital provides a biophysical and structural assessment of a critical immune regulating protein called human T-cell immunoglobulin and mucin domain containing protein-3 (hTIM-3).

11 Dec 2018

Insights into protein-protein interactions and methods for designing small molecule inhibitors

Proteins are polymers of amino acids that are linked by peptide bonds and they are one of the major classes of bio-molecules existing in a living organism. Proteins are involved in various cellular functions and events like cell signaling, cell adhesion, metabolic reactions, in the generation of immune response and many more.

10 Dec 2018

UC San Diego professor receives NCI Outstanding Investigator Award for cancer research

The National Cancer Institute has awarded David Cheresh, PhD, Distinguished Professor and vice chair of Pathology at University of California San Diego School of Medicine, with a $4.2 million Outstanding Investigator Award to continue his research into cancer's ability to overcome stress, gain drug resistance and metastasize.

10 Dec 2018

MIT researchers develop antimicrobial peptides from South American wasp’s venom

The venom of insects such as wasps and bees is full of compounds that can kill bacteria. Unfortunately, many of these compounds are also toxic for humans, making it impossible to use them as antibiotic drugs.

7 Dec 2018

New diagnostic tools may help identify breast cancer patients who could benefit from targeted therapies

A set of emerging diagnostic tools may help identify breast cancer patients who are most likely to benefit from therapies that target important enzymes fueling a range of subtypes, including BCRA-mutated and triple negative cancers.

7 Dec 2018

Molecule News and Research

Researchers discover Ebola-fighting protein in human cells

Advanced spectroscopic techniques used to prepare, characterize major degradation products of pralatrexate injection

New method to visualize small-molecule interactions inside cells

New mouse model shows potential for rapid identification of promising muscular dystrophy therapies

Unraveling the complexity of cancer biology can prompt new avenues for drug development

Researchers use INTEGRA's VIAFLO 96/384 to streamline the experimental workflow

IONTAS founder and pioneer in phage display technology attends Nobel Prize Award Ceremony

Targeting biochemical pathway may lead to new therapies for alleviating symptoms of anxiety disorders

Single tau molecule holds clues to help diagnose neurodegeneration in its earliest stages

Brazilian professors propose guidelines for therapeutic use of melatonin

Deadly combination: Drug cocktail induces cancer cell death by switching off energy supply

ESMO Immuno-Oncology Congress showcases novel technologies set to benefit many cancer patients

Research findings could lead to new targets for cancer-fighting therapeutics

Researchers identify potential diagnostic tool for Alzheimer’s disease

Researchers shed new light on how to combat Shiga and ricin toxins

Researchers capture high-resolution X-ray and NMR image of key immune regulator

Insights into protein-protein interactions and methods for designing small molecule inhibitors

UC San Diego professor receives NCI Outstanding Investigator Award for cancer research

MIT researchers develop antimicrobial peptides from South American wasp’s venom

New diagnostic tools may help identify breast cancer patients who could benefit from targeted therapies

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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