Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Scientists use a flash of light to erase and restore memory

Using a flash of light, scientists have inactivated and then reactivated a memory in genetically engineered rats. The study, supported by the National Institutes of Health, is the first cause-and-effect evidence that strengthened connections between neurons are the stuff of memory.

2 Jun 2014

Experts from ProfNet network available to discuss timely issues in coverage area

Below are experts from the ProfNet network that are available to discuss timely issues in your coverage area. If you are interested in interviewing any of the experts, please contact them via the contact information at the end of the listing.

31 May 2014

Eisai announces results from Phase III SELECT trial of lenvatinib evaluating PFS in patients with RR-DTC

Eisai Inc. announced today results from the Phase III SELECT trial of investigational agent lenvatinib evaluating progression-free survival (PFS) in patients with progressive radioiodine-refractory differentiated thyroid cancer (RR-DTC).

31 May 2014

CIRM grants $5.6 million to develop HIV/AIDS therapeutic using Sangamo's ZFN genome-editing technology

Sangamo BioSciences, Inc. announced that the California Institute for Regenerative Medicine (CIRM) has granted a $5.6 million Strategic Partnership Award to fund clinical studies at City of Hope to develop a potentially curative ZFP Therapeutic for HIV/AIDS based on the application of Sangamo's zinc finger nuclease (ZFN) genome-editing technology in hematopoietic stem/progenitor cells (HSPCs).

31 May 2014

Researchers create experimental blood test that determines BHI by gauging performance of mitochondria

Researchers at the University of Alabama at Birmingham School of Medicine have created an experimental blood test that, for the first time, determines a "Bioenergetic Health Index," or BHI, by gauging the performance of mitochondria, the cell's energy powerhouses.

30 May 2014

New research shows how misfolded proteins are precisely selected for degradation

It's almost axiomatic that misfolded proteins compromise how cells normally function and cause debilitating human disease, but how these proteins are detected and degraded within the body is not well understood.

30 May 2014

ALOXI injection receives FDA approval for prevention of nausea, vomiting associated with cancer chemotherapy

Eisai Inc. and Helsinn Group today announced the Food and Drug Administration (FDA) approval of ALOXI (palonosetron HCl) injection for the prevention of acute nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy, including highly emetogenic cancer chemotherapy, in children aged 1 month to less than 17 years.

29 May 2014

People with high levels of cynical distrust more likely to develop dementia, says study

People with high levels of cynical distrust may be more likely to develop dementia, according to a study published in the May 28, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology.

29 May 2014

Viewpoints: Political stand-off on insurance industry safeguards; VA's problems may lie in how government works

The Obama administration calls it an adjustment, Republicans call it a bailout and insurance companies call it the one thing that might keep them from raising rates and angering policyholders.

28 May 2014

Patients receiving steroids in hospital's ICU more likely to develop delirium, says study

New Johns Hopkins research suggests that critically ill patients receiving steroids in a hospital's intensive care unit (ICU) are significantly more likely to develop delirium. Results of their research, they say, suggest minimizing the use of steroids could reduce delirium in the ICU.

28 May 2014

Researchers develop active agents that may improve healing of inflammatory illnesses

It is something like the police force of our body: the immune system. It disables intruding pathogens, it dismantles injured tissue and boosts wound healing. In this form of 'self-defense' inflammatory reactions play a decisive role.

27 May 2014

Research findings could lead to new approach to Alzheimer’s prevention

In surprise findings, scientists at The Scripps Research Institute have discovered that a protein with a propensity to form harmful aggregates in the body when produced in the liver protects against Alzheimer’s disease aggregates when it is produced in the brain. The results suggest that drugs that can boost the protein’s production specifically in neurons could one day help ward off Alzheimer’s disease.

22 May 2014

Drugs that boost protein's production in neurons could help ward off Alzheimer's disease

In surprise findings, scientists at The Scripps Research Institute (TSRI) have discovered that a protein with a propensity to form harmful aggregates in the body when produced in the liver protects against Alzheimer's disease aggregates when it is produced in the brain.

22 May 2014

Researcher receives $1.5M grant from NIH to find clues into causes of Alzheimer's

Alzheimer's is a progressive brain disease that affects older adults, slowly destroys their memories and may cause dementia. According to estimates from the National Institutes of Health (NIH), the disease may affect as many as 5.1 million Americans.

22 May 2014

Combination of metformin and rapamycin shows potential in treating aging and related diseases

A proven approach to slow the aging process is dietary restriction, but new research in the Linus Pauling Institute at Oregon State University helps explain the action of a drug that appears to mimic that process - rapamycin.

21 May 2014

Study: Just and socially responsible layoff process is important for emotional health of workers

Researchers led by a University of North Texas Health Science Center epidemiologist found that a just and socially responsible layoff process is important for the emotional health of workers – a study that occurred during the most severe recession since the Great Depression.

21 May 2014

New compound restores learning, memory and other symptoms of AD in mice

A molecular compound developed by Saint Louis University scientists restored learning, memory and appropriate behavior in a mouse model of Alzheimer's disease, according to findings in the May issue of the Journal of Alzheimer's Disease.

21 May 2014

New cognitive test determines memory impairments due to AD and normal aging

Researchers have developed a new cognitive test that can better determine whether memory impairments are due to very mild Alzheimer's disease or the normal aging process.

21 May 2014

New optical approach to brain scanning for patients with electronic implants

Scientists have advanced a brain-scanning technology that tracks what the brain is doing by shining dozens of tiny LED lights on the head. This new generation of neuroimaging compares favorably to other approaches but avoids the radiation exposure and bulky magnets the others require, according to new research at Washington University School of Medicine in St. Louis.

20 May 2014

Researcher identify four new microRNAs involved in regulation of BDNF levels

Brain Derived Neurotrophic Factor (BDNF) regulates many processes including memory and learning in our daily tasks.

19 May 2014

Alzheimer's Disease News and Research

Further Reading

Scientists use a flash of light to erase and restore memory

Experts from ProfNet network available to discuss timely issues in coverage area

Eisai announces results from Phase III SELECT trial of lenvatinib evaluating PFS in patients with RR-DTC

CIRM grants $5.6 million to develop HIV/AIDS therapeutic using Sangamo's ZFN genome-editing technology

Researchers create experimental blood test that determines BHI by gauging performance of mitochondria

New research shows how misfolded proteins are precisely selected for degradation

ALOXI injection receives FDA approval for prevention of nausea, vomiting associated with cancer chemotherapy

People with high levels of cynical distrust more likely to develop dementia, says study

Viewpoints: Political stand-off on insurance industry safeguards; VA's problems may lie in how government works

Patients receiving steroids in hospital's ICU more likely to develop delirium, says study

Researchers develop active agents that may improve healing of inflammatory illnesses

Research findings could lead to new approach to Alzheimer’s prevention

Drugs that boost protein's production in neurons could help ward off Alzheimer's disease

Researcher receives $1.5M grant from NIH to find clues into causes of Alzheimer's

Combination of metformin and rapamycin shows potential in treating aging and related diseases

Study: Just and socially responsible layoff process is important for emotional health of workers

New compound restores learning, memory and other symptoms of AD in mice

New cognitive test determines memory impairments due to AD and normal aging

New optical approach to brain scanning for patients with electronic implants

Researcher identify four new microRNAs involved in regulation of BDNF levels

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