Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Researchers identify heart-specific form of protein that protects against irregular heartbeats

Researchers at the Cedars-Sinai Heart Institute have identified a heart-specific form of a protein, BIN1, responsible for sculpting tiny folds in pockets that are present on the surface of heart muscle cells.

19 May 2014

Research professor of Emory receives 2014 MetLife Foundation Awards for Medical Research

Lary C. Walker, PhD, research professor of neuropharmacology and neurologic diseases and associate professor of neurology, Yerkes National Primate Research Center, Emory University, is a recipient of the 2014 MetLife Foundation Awards for Medical Research. The winners were recognized at a scientific briefing and awards ceremony today in New York.

16 May 2014

MetLife announces recipients of 2014 MetLife Foundation Awards for Medical Research

MetLife Foundation today announced the recipients of the 2014 MetLife Foundation Awards for Medical Research.

16 May 2014

BRF expands study to evaluate whether structured exercise slows progression of AD

The Brain Research Foundation (BRF) today announced that it will provide a major grant that will further research funded by the National Institute of Aging (NIA) which evaluated whether structured exercise slows the progression of Alzheimer's disease.

15 May 2014

Transition Therapeutics begins TT-401 Phase 2 clinical study for treatment of type 2 diabetes

Transition Therapeutics Inc. today announced the dosing of the first patient in a Phase 2 clinical study of TT-401 (LY2944876), a drug candidate for the treatment of type 2 diabetes.

15 May 2014

Suppressing hyperactivity of calcium channels alleviates familial Alzheimer's disease

In 2008, researchers at the Perelman School of Medicine at the University of Pennsylvania showed that mutations in two proteins associated with familial Alzheimer's disease (FAD) disrupt the flow of calcium ions within neurons.

15 May 2014

Anti-depressants could slow onset of Alzheimer's disease

A University of Pennsylvania researcher has discovered that the common selective serotonin reuptake inhibitor (SSRI) citalopram arrested the growth of amyloid beta, a peptide in the brain that clusters in plaques that are thought to trigger the development of Alzheimer's disease (AD).

15 May 2014

Antidepressant stops growth of plaques in mouse model of Alzheimer's disease

A commonly prescribed antidepressant can reduce production of the main ingredient in Alzheimer's brain plaques, according to new research at Washington University School of Medicine in St. Louis and the University of Pennsylvania.

15 May 2014

Researchers develop new high-tech device for transferring DNA into cells

The ability to transfer a gene or DNA sequence from one animal into the genome of another plays a critical role in a wide range of medical research-including cancer, Alzheimer's disease, and diabetes.

14 May 2014

Scientists discover novel protein fragments that may protect against Alzheimer's disease

The devastating loss of memory and consciousness in Alzheimer's disease is caused by plaque accumulations and tangles in neurons, which kill brain cells.

14 May 2014

Prolong exposure to paint, glue is detrimental for brain

People who are exposed to paint, glue or degreaser fumes at work may experience memory and thinking problems in retirement, decades after their exposure, according to a study published in the May 13, 2014, print issue of Neurology®, the medical journal of the American Academy of Neurology.

13 May 2014

GE Healthcare, Tesla Engineering announce collaboration to develop ultra high-field MRI systems

Today at the joint meeting of the International Society for Magnetic Resonance in Medicine and the European Society for Magnetic Resonance in Medicine and Biology, GE Healthcare and Tesla Engineering Ltd. announced that they will collaborate together to produce 7.0 tesla (7.0T) human whole-body magnetic resonance imaging (MRI) scanners, and build upon the ten year history of GE innovations in this advanced, technical field.

12 May 2014

People with longevity gene have improved brain skills

Scientists showed that people who have a variant of a longevity gene, called KLOTHO, have improved brain skills such as thinking, learning and memory regardless of their age, sex, or whether they have a genetic risk factor for Alzheimer's disease.

12 May 2014

Study of rare childhood neurodegenerative diseases identifies new source of DNA damage

St. Jude Children's Research Hospital scientists studying two rare, inherited childhood neurodegenerative disorders have identified a new, possibly common source of DNA damage that may play a role in other neurodegenerative diseases, cancer and aging.

12 May 2014

Chinese herbal formula protects against hippocampal neurons death via non-classical estrogen pathway

Amyloid-β (Aβ) plaques and neurofibrillary tangles are the main pathological hallmarks of Alzheimer's disease, as well as the loss of neurons and synapses. recent reports have shown that estrogen exerts neuroprotective effects.

9 May 2014

Mice study shows specific energy source responsible for performing complex cognitive functions

New research suggests that certain types of brain cells may be "picky eaters," seeming to prefer one specific energy source over others.

9 May 2014

Finding has implications for understanding cognitive decline in degenerative diseases

New research suggests that certain types of brain cells may be "picky eaters," seeming to prefer one specific energy source over others. The finding has implications for understanding the cognitive decline seen in aging and degenerative diseases such as Alzheimer's and multiple sclerosis.

8 May 2014

RAAV/ABAD-DP-6His generates fusion peptide that protects PC12 cells from oxidative stress injury

The effects of Amyloid beta (Aβ)-Aβ-binding alcohol dehydrogenase (ABAD) may exacerbate Alzheimer's disease pathology.

8 May 2014

Researchers create universal flu vaccine

Researchers at the University of Texas Medical Branch are working to create a universal flu vaccine - one that could eliminate the need for an annual flu shot.

8 May 2014

Common drug may improve blood flow in muscles of boys with Duchenne muscular dystrophy

A drug typically prescribed for erectile dysfunction or increased pressure in the arteries may help improve blood flow in the muscles of boys with Duchenne muscular dystrophy, according to a study published in the May 7, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology.

8 May 2014

Alzheimer's Disease News and Research

Further Reading

Researchers identify heart-specific form of protein that protects against irregular heartbeats

Research professor of Emory receives 2014 MetLife Foundation Awards for Medical Research

MetLife announces recipients of 2014 MetLife Foundation Awards for Medical Research

BRF expands study to evaluate whether structured exercise slows progression of AD

Transition Therapeutics begins TT-401 Phase 2 clinical study for treatment of type 2 diabetes

Suppressing hyperactivity of calcium channels alleviates familial Alzheimer's disease

Anti-depressants could slow onset of Alzheimer's disease

Antidepressant stops growth of plaques in mouse model of Alzheimer's disease

Researchers develop new high-tech device for transferring DNA into cells

Scientists discover novel protein fragments that may protect against Alzheimer's disease

Prolong exposure to paint, glue is detrimental for brain

GE Healthcare, Tesla Engineering announce collaboration to develop ultra high-field MRI systems

People with longevity gene have improved brain skills

Study of rare childhood neurodegenerative diseases identifies new source of DNA damage

Chinese herbal formula protects against hippocampal neurons death via non-classical estrogen pathway

Mice study shows specific energy source responsible for performing complex cognitive functions

Finding has implications for understanding cognitive decline in degenerative diseases

RAAV/ABAD-DP-6His generates fusion peptide that protects PC12 cells from oxidative stress injury

Researchers create universal flu vaccine

Common drug may improve blood flow in muscles of boys with Duchenne muscular dystrophy

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