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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Inflammation at the heart’s core: What clinicians and families can do now

Chronic low-grade inflammation is a key driver of cardiovascular disease, even when cholesterol is controlled. The ACC’s 2025 Scientific Statement highlights hsCRP as a routine risk marker and outlines lifestyle and pharmacologic anti-inflammatory strategies for prevention and treatment.

30 Sep 2025

Discovery of EUDAL reveals new mechanism behind chemotherapy resistance in oral cancer

Oral cancer is one of the most common head and neck cancers worldwide, with hundreds of thousands of new cases diagnosed every year. Despite advances in surgery, radiotherapy, and chemotherapy, survival rates remain poor.

30 Sep 2025

Tagomics publishes a new approach to genome-wide epigenomic profiling

Tagomics Ltd., a pioneering biomarker discovery and diagnostics company, today announced the publication of a peer-reviewed study in Cell Reports Methods, underpinning its epigenomic profiling technology, Active-Seq, the basis of Tagomics' Activace™ platform.

30 Sep 2025

Group-based and online counselling reduces diabetes risk in high-risk men

Group-based and online lifestyle counselling can support middle-aged and older men in making health-promoting dietary changes. These dietary changes, in turn, reduce the risk of type 2 diabetes, especially among men with a high genetic risk, a study conducted at the University of Eastern Finland shows.

30 Sep 2025

Molecular fingerprint predicts physical fitness in older adults

Could a simple blood test reveal how well someone is aging? A team of researchers led by Wolfram Weckwerth from the University of Vienna, Austria, and Nankai University, China, has combined advanced metabolomics with cutting-edge machine learning and a novel network modeling tool to uncover the key molecular processes underlying active aging.

30 Sep 2025

Gene expression test identifies prostate cancer patients who benefit from hormone therapy

A new randomized study finds that a lab test that reads tumor genes can identify which patients with recurrent prostate cancer will benefit from adding hormone therapy to radiation after surgery - the first predictive biomarker in this setting.

29 Sep 2025

Super-resolution imaging unlocks the role of transporter nanoclusters in tumor metabolism

Serine serves as a metabolic nexus in tumors, coordinating one-carbon metabolism, nucleotide synthesis, and redox regulation. In recent years, targeting the serine metabolic pathway, particularly the rate-limiting enzyme PHGDH, has attracted considerable attention as a promising anticancer strategy.

29 Sep 2025

IGF2BP3 protein drives leukemia growth by linking metabolism and RNA control

Cancer cells are relentless in their quest to grow and divide, often rewiring their metabolism and modifying RNA to stay one step ahead.

26 Sep 2025

Breakthrough in predicting Parkinson’s and dementia in people with REM sleep behavior disorder

An international research team led by Université de Montréal medical professor Shady Rahayel has made a major breakthrough in predicting neurodegenerative diseases.

26 Sep 2025

Drinking less water daily spikes your stress hormone

Findings indicate that low hydration is associated with increased cortisol spikes during stress, potentially influencing long-term health risks.

26 Sep 2025

Advanced workflow automation and scalable image analysis in spatial biology

ZEISS Microscopy and Concept Life Sciences, a UK-based contract research organization (CRO), announced their collaboration aimed at pioneering new approaches to workflow automation and scalable image analysis in spatial biology.

From Concept Life Sciences 26 Sep 2025

Study identifies key molecular and clinical biomarkers for MASLD

The causal biomarkers for metabolic dysfunction-associated steatotic liver disease (MASLD) and their clinical value remain unclear.

25 Sep 2025

Study explains how genetics and lifestyle combined to keep a 117-year-old healthy

Scientists conducted a multiomics study of the world’s oldest verified person (117 years), uncovering protective genetic, immune, metabolic, microbiome, and epigenetic traits that supported her exceptional longevity. These findings highlight how aging and disease may, under rare circumstances, be decoupled.

25 Sep 2025

UdeM studies make a major breakthrough in predicting neurodegenerative diseases

An international research team led by Université de Montréal medical professor Shady Rahayel has made a major breakthrough in predicting neurodegenerative diseases.

25 Sep 2025

Groundbreaking MRI technique reveals microvascular pulsations in the aging brain

Researchers at the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC have developed a groundbreaking brain imaging technique that reveals how tiny blood vessels in the brain pulse with each heartbeat-changes that may hold clues to aging and diseases such as Alzheimer's.

25 Sep 2025

University of Utah launches landmark study linking blood pressure and brain health

In six massive laboratory freezers at the University of Utah, nearly 40,000 blood samples wait in frozen stasis.

24 Sep 2025

Reversing age-related vision loss with retinal lipid therapy

Changes in vision are often a common sign of aging. If you sit in a dimly lit restaurant with anyone over the age of 60, you'll likely hear the person say, "Hold on - let me pull out my cell phone. I need more light to read the menu!" But what if we could reverse age-related visual decline?

24 Sep 2025

Blood and brain biomarkers transform how doctors confirm Alzheimer’s disease

A new Lancet review proposes a three-wave diagnostic pathway that combines clinical expertise with blood, CSF, and PET biomarkers. This approach aims to deliver earlier, more accurate, and more equitable Alzheimer’s disease diagnosis worldwide.

24 Sep 2025

How food choices and cooking methods drive brain inflammation and disease

Researchers reviewing evidence in NeuroSci show how dietary AGEs and their interaction with RAGE drive oxidative stress, inflammation, and neurodegeneration. They highlight how cooking methods and diet choices could lower AGE burden and protect brain health, while calling for rigorous clinical trials.

24 Sep 2025