Lymph Node News and Research

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Lymph is clear or white fluid that travels through vessels, moves within tissues and work to keep all the parts of the body clean. After passing through the channels of the lymphatic system they drain into the lymph nodes. The lymph nodes act as filters along the lymphatic system. These nodes trap germs like bacteria, viruses, toxins as well as cancer cells and ensure that these are removed from the body.

Study: Size of lesions seen on CT images varies significantly with level of radiation doses

The estimated size of chest lymph nodes and lung nodules seen on CT images varies significantly when the same nodes or nodules are examined using lower versus higher doses of radiation, a new study shows. The size of lymph nodes and lung nodules is an important determinant of treatment and treatment success.

17 Apr 2013

UCSF study evaluates genetic predictors of lymphedema in women

A new UCSF study has found a clear association between certain genes and the development of lymphedema, a painful and chronic condition that often occurs after breast cancer surgery and some other cancer treatments.

17 Apr 2013

Navidea presents Phase 3 Lymphoseek study results at international symposium in Athens

Navidea Biopharmaceuticals, Inc., a biopharmaceutical company focused on precision diagnostic radiopharmaceuticals, today announced that a presentation of results from its Phase 3 clinical trial of Lymphoseek (technetium 99m tilmanocept) Injection in patients with head and neck squamous cell carcinoma received the 1st Investigator Award at the 2nd InternationaI Symposium on Thoracic and Upper Aerodigestive Malignancies.

15 Apr 2013

$Pharmacyclics presents positive results of ibrutinib Phase II trial in untreated, relapsed and refractory CLL patients$

Pharmacyclics presents positive results of ibrutinib Phase II trial in untreated, relapsed and refractory CLL patients

Pharmacyclics, Inc. today announced results from a Phase II trial of the investigational oral agent ibrutinib which demonstrated rapid and sustained disease control as a monotherapy in untreated, relapsed and refractory chronic lymphocytic leukemia (CLL) patients, irrespective of characteristics that predict poor outcomes to chemoimmunotherapy.

11 Apr 2013

BRAF genetic mutation increases mortality among patients with papillary thyroid cancer

Presence of the genetic mutation BRAF V600E was significantly associated with increased cancer-related death among patients with papillary thyroid cancer (PTC); however, because overall mortality in PTC is low and the association was not independent of tumor characteristics, how to use this information to manage mortality risk in patients with PTC is unclear, according to a study in the April 10 issue of JAMA, a Genomics theme issue.

10 Apr 2013

New device that detects breast cancer metastasis is extending its market reach

A device co-developed by a University of Houston (UH) physicist to detect the spread of breast cancer and allow physicians to better plan intervention is extending its market reach, bringing it another step closer to clinical trials in the U.S.

10 Apr 2013

Prostate cancer prognosis tables: an interview with Dr John B. Eifler, Brady Urological Institute of Johns Hopkins

Prostate cancer is the most common cancer in men. Despite many advances in diagnosis and treatment over the past two decades, it remains the second most common cause of cancer related death in men.

28 Mar 2013

New imaging agent detects, maps cancers that have reached lymph nodes

Researchers at the University of California, San Diego School of Medicine have shown that a new imaging dye, designed and developed at UC San Diego Moores Cancer Center, is an effective agent in detecting and mapping cancers that have reached the lymph nodes.

21 Mar 2013

Small kidney tumours have aggressive potential and should be treated, study says

Small kidney tumours have an aggressive potential and should be treated, according to a the results of a large multicentre study presented at the 28th Annual EAU Congress in Milan.

18 Mar 2013

Lymphoseek receives FDA approval for breast cancer, melanoma

The U.S. Food and Drug Administration today approved Lymphoseek (technetium Tc 99m tilmanocept) Injection, a radioactive diagnostic imaging agent that helps doctors locate lymph nodes in patients with breast cancer or melanoma who are undergoing surgery to remove tumor-draining lymph nodes.

14 Mar 2013

Immune system B cells play crucial role in defence of pathogens

Immune system B cells play a crucial role in the defence of pathogens; when they detect such an intruder, they produce antibodies that help to combat the enemy.

13 Mar 2013

EORTC survey looks at common practices in melanoma surgery

The European Organisation for Research and Treatment of Cancer (EORTC) has conducted an international survey of 75 melanoma centres on their behaviours and practices. The survey, which was conducted between 2003-2005, looked at common surgical practices in melanoma surgery (resection margins, sentinel node biopsy and lymph node dissection), as well as surgical management of distant metastases and the use of Isolate Limb Perfusion.

1 Mar 2013

Anesthetics during breast cancer surgery may affect development of chronic pain

In women with breast cancer, the choice of anesthetic used for mastectomy may affect the risk of developing long-term pain after surgery, according to a study in the March issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

28 Feb 2013

Trends in patient worry and risk-reducing behaviors in women undergoing breast cancer treatment

Women who have had the lymph nodes under their arm surgically removed during breast cancer treatment are warned to avoid certain practices that can cause lymphedema-a condition that causes chronic, painless swelling in the arm.

26 Feb 2013

Scientists discover new subgroups of GC patients with different disease's characteristics

A collaboration between Portuguese and Italian scientists has discovered new subgroups of stomach cancer patients with different disease's characteristics, an information that is hoped will help improving the clinical management of a disease that still kills a dismaying 3 out of 4 patients.

18 Feb 2013

Structured training program improves lymph node biopsy standards

An established training program in sentinel lymph node biopsy ensures patient safety during the adoption of a new technique by enabling surgeons to achieve a very high localization rate and low false-negative rate throughout their training.

15 Feb 2013

MicroRNA can be used to define four subtypes of triple-negative breast cancer

A new, large-scale study of triple-negative breast cancer shows that small molecules called microRNA can be used to define four subtypes of this aggressive malignancy.

11 Feb 2013

Subclinical hypothyroidism not prognostic in thyroid carcinoma

Subclinical hypothyroidism is not an independent predictor for clinical outcomes in patients with papillary thyroid carcinoma, research shows.

5 Feb 2013

MammaPrint breast cancer test can help women avoid chemotherapy

The MammaPrint breast cancer test can dramatically reduce the number of women who need to undergo chemotherapy to treat the disease, according to a newly published study.

5 Feb 2013

Maimonides, Navidea to evaluate Lymphoseek use in lymphatic mapping for colorectal cancer

Navidea Biopharmaceuticals, Inc., a biopharmaceutical company focused on precision diagnostic radiopharmaceuticals, today announced it has entered into an agreement to collaborate with Maimonides Medical Center to investigate the utility of Lymphoseek (technetium Tc 99m tilmanocept) Injection in lymphatic mapping procedures for colorectal cancer.

5 Feb 2013

Lymph Node News and Research

Further Reading

Study: Size of lesions seen on CT images varies significantly with level of radiation doses

UCSF study evaluates genetic predictors of lymphedema in women

Navidea presents Phase 3 Lymphoseek study results at international symposium in Athens

Pharmacyclics presents positive results of ibrutinib Phase II trial in untreated, relapsed and refractory CLL patients

BRAF genetic mutation increases mortality among patients with papillary thyroid cancer

New device that detects breast cancer metastasis is extending its market reach

Prostate cancer prognosis tables: an interview with Dr John B. Eifler, Brady Urological Institute of Johns Hopkins

New imaging agent detects, maps cancers that have reached lymph nodes

Small kidney tumours have aggressive potential and should be treated, study says

Lymphoseek receives FDA approval for breast cancer, melanoma

Immune system B cells play crucial role in defence of pathogens

EORTC survey looks at common practices in melanoma surgery

Anesthetics during breast cancer surgery may affect development of chronic pain

Trends in patient worry and risk-reducing behaviors in women undergoing breast cancer treatment

Scientists discover new subgroups of GC patients with different disease's characteristics

Structured training program improves lymph node biopsy standards

MicroRNA can be used to define four subtypes of triple-negative breast cancer

Subclinical hypothyroidism not prognostic in thyroid carcinoma

MammaPrint breast cancer test can help women avoid chemotherapy

Maimonides, Navidea to evaluate Lymphoseek use in lymphatic mapping for colorectal cancer

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