Molecular Biology News and Research

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Molecular biology is the study of biology at a molecular level. The field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry. Molecular biology chiefly concerns itself with understanding the interactions between the various systems of a cell, including the interactions between DNA, RNA and protein biosynthesis as well as learning how these interactions are regulated.

Columbia study reveals bacteria create free-floating genes, challenging genetic code norms

Since the genetic code was first deciphered in the 1960s, our genes seemed like an open book. By reading and decoding our chromosomes as linear strings of letters, like sentences in a novel, we can identify the genes in our genome and learn why changes in a gene's code affect health.

9 Aug 2024

New insights into topoisomerase I inhibition reveal potential pathways for cancer therapies

A research group at the University of Bologna has identified, for the first time, the specific location and genomic context where DNA breaks occur due to the inhibition of the topoisomerase I, a protein crucial for many biological processes in cells.

8 Aug 2024

Ribosomes in cells play a crucial role in protein folding

Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in cells, described in their paper in Nature.

7 Aug 2024

Novel blood test could predict chronic lung disease in preterm babies within hours of birth

A blood test can help predict which preterm babies will go onto develop chronic lung disease, allowing for earlier diagnosis and more targeted treatments, according to a new study.

7 Aug 2024

Study advances understanding of complex neurological disorder

To effectively treat a disease or disorder, doctors must first know the root cause. Such is the case for developmental and epileptic encephalopathies (DEEs), whose root causes can be hugely complex and heterogeneous. Scientists at St. Jude Children's Research Hospital demonstrated the value of DNA methylation patterns for identifying the root cause of DEEs, showing specific gene methylation and genome-wide methylation "episignatures" can help identify the genes that cause DEE. The findings were published today in Nature Communications.

7 Aug 2024

New dual-purpose contrast agent revolutionizes PET and MRI integration for enhanced diagnosis

A research team from IOCB Prague, working in collaboration with the University of Tübingen, Germany, and the Faculty of Science, Charles University, has developed a new type of contrast agent that can be used in both magnetic resonance imaging (MRI) and positron emission tomography (PET).

5 Aug 2024

Study finds fourfold increase in risk of overt hypothyroidism after diagnosis of gestational subclinical hypothyroidism

A new study has shown that subclinical hypothyroidism diagnosed before 21 weeks of pregnancy is associated with more than fourfold higher rates of overt hypothyroidism or thyroid replacement therapy within 5 years of delivery.

2 Aug 2024

How machine learning is accelerating research in structural biology

For Lucas Farnung, there is no question more fascinating than how a single fertilized egg develops into a fully-functioning human.

2 Aug 2024

Using advanced CRISPR to boost efficiency of CAR-T cell therapies

CAR-T cells are highly effective in treating selected blood cancers. However, challenges remain with this new therapy, which was first approved in 2017 in the USA and a year later in Europe for treating acute lymphoblastic leukemia (ALL).

2 Aug 2024

Microbes play key role in carcinogenesis

At any given time, over 10 trillion microbes call our guts their home. From breaking down nutrients in our food to strengthening our immunity against pathogens, these microbes play an essential role in how we interact with the world. This includes – as shown in a new study by EMBL researchers and collaborators at the University of Split, Croatia – the way the body responds to carcinogens and develops cancer.

1 Aug 2024

New discovery unveils key process in DNA repair pathway

An elegant collaboration between researchers in the UK's two core-funded Medical Research Council Research Institutes, the Laboratory of Medical Sciences (LMS) in London and the Laboratory of Molecular Biology (LMB) in Cambridge, has solved a decades-old mystery which could pave the way to better cancer treatments in the future.

31 Jul 2024

Penn researchers find a way to tease apart genetic and environmental effects of disease risk

Every disease is shaped by a genetic component as well as environmental factors like air pollution, climate and socioeconomic status.

30 Jul 2024

Review highlights the interplay of TGF-β and HIPPO pathways in liver regeneration and disease

The liver's ability to communicate with other organs is crucial for maintaining homeostasis, particularly through signaling pathways.

30 Jul 2024

Epigenetic reprogramming and hypothalamic changes in metabolic syndrome

Metabolic syndrome (MetS) is a multifaceted disorder that impacts approximately 20–25% of the global population.

30 Jul 2024

Deciphering miRNA-mediated regulation of liver regeneration: New insights

The liver, a vital organ involved in numerous essential physiological processes such as bile production, plasma protein synthesis, nutrient absorption, detoxification, vitamin storage, macronutrient metabolism, and immune support, has a remarkable regenerative capacity.

29 Jul 2024

Molecular Biology News and Research

Further Reading

Columbia study reveals bacteria create free-floating genes, challenging genetic code norms

New insights into topoisomerase I inhibition reveal potential pathways for cancer therapies

Ribosomes in cells play a crucial role in protein folding

Novel blood test could predict chronic lung disease in preterm babies within hours of birth

Study advances understanding of complex neurological disorder

New dual-purpose contrast agent revolutionizes PET and MRI integration for enhanced diagnosis

Study finds fourfold increase in risk of overt hypothyroidism after diagnosis of gestational subclinical hypothyroidism

How machine learning is accelerating research in structural biology

Using advanced CRISPR to boost efficiency of CAR-T cell therapies

Microbes play key role in carcinogenesis

New discovery unveils key process in DNA repair pathway

Penn researchers find a way to tease apart genetic and environmental effects of disease risk

Review highlights the interplay of TGF-β and HIPPO pathways in liver regeneration and disease

Epigenetic reprogramming and hypothalamic changes in metabolic syndrome

Deciphering miRNA-mediated regulation of liver regeneration: New insights

Advancing hepatic cell carcinoma treatment through mitochondrial DNA targeting

Understanding iron overload in β-thalassemia: Mechanisms, diagnosis, and treatments

Understanding the epigenetic regulation of hepatic stellate cells in NAFLD

Creating the first genetically susceptible mice for late-onset Alzheimer's

Challenging antibiotic resistance with dual-action macrolones

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