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Study clarifies how spermine can guard against Alzheimer’s and Parkinson’s

Researchers at the Paul Scherrer Institute PSI have clarified how spermine - a small molecule that regulates many processes in the body's cells - can guard against diseases such as Alzheimer's and Parkinson's: it renders certain proteins harmless by acting a bit like cheese on noodles, making them clump together.

21 Nov 2025

New light-activated method revolutionizes creation of drug building blocks

A team of organic and computational chemists at the University of Minnesota Twin Cities have created a new, modern tool to make the process of creating pharmaceuticals and agrochemicals faster, cost-effective, and energy-efficient.

21 Nov 2025

CAR T cell therapy could be a highly effective tool against atherosclerosis

A pioneering preclinical study has shown that CAR T cell therapy-a personalized form of immunotherapy used in cancer treatment-could be a highly effective tool against atherosclerosis, the condition where a build-up of plaque in the arteries reduces blood flow, leading to heart attacks and strokes.

21 Nov 2025

Oral GLP-1 pill shows strong weight loss and blood sugar benefits in adults with diabetes

A new oral GLP-1 medication can help adults with obesity and Type 2 diabetes lose more weight and improve their blood sugar levels compared to a placebo, according to findings from the ATTAIN-2 trial led by a UTHealth Houston researcher.

20 Nov 2025

RNA-based cocktail shows promise against glioblastoma

A patented RNA-based cocktail developed at the Italian Institute of Technology (IIT-Istituto Italiano di Tecnologia) has emerged as a promising active agent against tumors of the central nervous system, such as glioblastoma.

20 Nov 2025

New patch may help heal the heart after a heart attack

A new patch developed by Texas A&M University researcher Dr. Ke Huang may offer a way to help the heart heal after a heart attack.

19 Nov 2025

Research reveals new insights into the biology of recurrent miscarriage

Researchers at the Victor Chang Cardiac Research Institute, University of Sydney, and the Royal Hospital for Women have uncovered important new insights into the biology of recurrent miscarriage - a devastating condition that affects up to one in fifty couples trying to conceive.

19 Nov 2025

Blocking mir-21 shows promise for slowing bladder cancer growth

Bladder cancer ranks among the ten most common types of cancer worldwide. The main treatment is bladder removal surgery, and despite advances in systemic therapies, recurrence is frequent in the most aggressive forms of the disease.

18 Nov 2025

New antibody strategy shows promise for halting cyst growth in polycystic kidney disease

Polycystic kidney disease (PKD) is a debilitating hereditary condition in which fluid-filled sacs form and proliferate in the kidneys. Over time, the painful, growing cysts rob the organs of their function, often leading to dialysis in advanced cases.

18 Nov 2025

DeepTarget tool uncovers primary and secondary drug targets across cancer types

One person's side effect could be another person's treatment if we expand our perspective on small molecule drug targets, according to a new study published November 5, 2025, in npj Precision Oncology.

18 Nov 2025

Harnessing a natural blood vessel molecule to develop broad mRNA antivirals

In a surprising discovery, a 'sticky molecule' that occurs naturally in our blood vessels could be both a culprit behind blood clots and organ failure during COVID and long COVID and the key to new treatments to counter COVID-related viruses.

18 Nov 2025

Muscle-driven gene therapy shows promise for protecting memory in Alzheimer’s

Alzheimer's disease (AD) is a devastating cause of memory loss and cognitive decline, for which no curative treatment is available.

18 Nov 2025

New malaria treatment holds promise against rising drug resistance

The first new malaria treatment in decades holds promise against rising drug resistance after Swiss drugmaker Novartis announced it was as effective at treating the disease as established treatments.

17 Nov 2025

Testing nicotinamide riboside as a potential aid for long COVID recovery

Chao-Yi Wu, PhD, OT, from the Department of Neurology and Edmarie Guzmán-Vélez, PhD, of the Department of Psychiatry at Mass General Brigham, are the lead and senior authors of a paper published in eClinicalMedicine, "Effects of Nicotinamide Riboside on NAD+ Levels, Cognition, and Symptom Recovery in Long-COVID: A Randomized Controlled Trial."

14 Nov 2025

Synthesizing a powerful cancer-fighting molecule from sea sponges

Yale chemists have synthesized a complex, potentially cancer-fighting molecule found in sea sponges discovered off the coast of South Korea.

14 Nov 2025

DeepTarget: A new tool for drug repurposing in oncology

14 Nov 2025

New technique revolutionizes the design of drugs that target ion channels

An international team involving the Institute of Chemical Research, a joint centre of the University of Seville and the Spanish National Research Council, has developed a new technique that will accelerate the design of drugs that target ion channels, a type of cell membrane protein involved in numerous diseases, ranging from psychiatric disorders to various types of cancer.

14 Nov 2025

Scientists reveal how prolonged UV exposure weakens cellular defense against skin cancer

Sunlight is vital for human health as it helps the body produce essential nutrients, such as vitamin D. However, too much sun exposure can significantly increase the risk of skin cancer.

13 Nov 2025

Lymphoma resistance mechanisms and future therapies

A new review was published in Volume 12 of Oncoscience on October 13, 2025, titled "Targeted therapies and resistance mechanisms in lymphoma: Current landscape and emerging solutions."

13 Nov 2025

TRIMTECH Therapeutics appoints Dr Mike Hutton to Scientific Advisory Board

TRIMTECH Therapeutics, a biotech company creating novel, small molecule therapeutics that selectively degrade protein aggregates, to combat neurodegenerative diseases, today announced the appointment of Dr Mike Hutton to its Scientific Advisory Board (SAB).

From TRIMTECH Therapeutics 12 Nov 2025