Prophylaxis News and Research

RSS

Wits doctors transplant liver from HIV positive mother to her child with end-stage liver disease

This was the ethical dilemma faced by doctors at Wits Donald Gordon Medical Centre to save a child's life.

4 Oct 2018

Genentech announces Phase III study results of baloxavir marboxil in people at high risk of flu

Genentech, a member of the Roche Group, today announced that the Phase III CAPSTONE-2 study showed treatment with baloxavir marboxil significantly reduced the time to improvement of influenza symptoms versus placebo in people at high risk of serious complications from the flu, which includes adults 65 years of age or older, or those who have conditions such as asthma, chronic lung disease, morbid obesity, or heart disease.

4 Oct 2018

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Seattle Genetics, Inc. and Takeda Pharmaceutical Company Limited announced today that the phase 3 ECHELON-2 clinical trial met its primary endpoint.

1 Oct 2018

Cidara initiates Phase 3 clinical trial to evaluate efficacy, safety of rezafungin to treat invasive candidiasis

Cidara Therapeutics, Inc., a biotechnology company developing novel anti-infectives including immunotherapies, today announced that the first trial site has been activated for ReSTORE, a Phase 3 clinical trial evaluating the efficacy and safety of the company's lead antifungal, rezafungin, to treat candidemia and invasive candidiasis.

27 Sep 2018

Risk-profiling can help improve preventive measures against HIV

That men who have sex with men run a greater risk of HIV than others has been known since the virus was discovered. However a thesis from Karolinska Institutet now shows that it is a small sub-group of these men who account for the greater part of the risk increase.

26 Sep 2018

ADCETRIS drug receives approval in Japan as frontline treatment option for Hodgkin lymphoma

Seattle Genetics, Inc. today announced that its collaborator, Takeda Pharmaceutical Company Limited, has received approval from the Japanese Ministry of Health, Labour and Welfare for ADCETRIS (brentuximab vedotin) in combination with doxorubicin, vinblastine and dacarbazine as a frontline treatment option for CD30-positive Hodgkin lymphoma patients in Japan.

24 Sep 2018

Australia's HIV diagnoses hit seven year low

According to latest numbers from the Kirby Institute at the University of New South Wales (UNSW), the rates of HIV are on the rise among heterosexuals in Australia.

23 Sep 2018

$CHMP grants positive opinion for VENCLYXTO plus rituximab for treating relapsed/refractory CLL$

CHMP grants positive opinion for VENCLYXTO plus rituximab for treating relapsed/refractory CLL

AbbVie, a research-based global biopharmaceutical company, announced today that the Committee for Medicinal Products for Human Use of the European Medicines Agency has granted a positive opinion for VENCLYXTO® in combination with rituximab for the treatment of patients with relapsed/refractory chronic lymphocytic leukemia who have received at least one prior therapy.

21 Sep 2018

SLU's College professor receives NIH grant to develop I-TEST project

ST. LOUIS - Nigerian youth are at the epicenter of an expanding HIV crisis in Sub-Saharan Africa. As a country, Nigeria ranks second in the in the world in new HIV-Infections among youth, youth living with HIV and AIDS-related death among a youth population.

20 Sep 2018

New program combines basic science and social benefits to address HIV risk among young women

A program established by investigators from the Ragon Institute of Massachusetts General Hospital, MIT and Harvard is addressing the persistently elevated risk of HIV infection among young women in South Africa from two angles - first, investigating biological factors that modulate infection risk along with the early immunologic events following viral exposure, and second, alleviating the socioeconomic factors that limit opportunities for young women, the group at greatest risk of infection in the region of the world hardest hit by the HIV epidemic.

17 Sep 2018

FDA approves new treatment for people with hairy cell leukemia

AstraZeneca and MedImmune, its global biologics research and development arm, announced today that the US Food and Drug Administration has approved LUMOXITI (moxetumomab pasudotox-tdfk) for the treatment of adult patients with relapsed or refractory hairy cell leukemia who have received at least two prior systemic therapies, including treatment with a purine nucleoside analog.

14 Sep 2018

CNS releases new clinical practice guidelines for thoracolumbar spine trauma

The Congress of Neurological Surgeons has issued new clinical practice guidelines on the evaluation and treatment of patients with thoracolumbar spine trauma.

7 Sep 2018

Subcutaneous injection of new protein helps treat hemophilia more effectively

Patients with hemophilia bleed spontaneously or following trauma. The most common sites of bleeding are into joints, but bleeds can also happen into any tissue in the body including the muscles, brain, or eyes.

31 Aug 2018

Understanding How Antibodies Shape the Gut Microbiome

Dr. Keiichiro Suzuki discusses the importance of IgA in the human body, and his recent research study, which showed that IgA interacts with the gut microbiome and promotes the growth of healthy bacteria.

20 Aug 2018

Advances in treating hep C lead to new option for transplant patients

After her kidneys failed from the same illness that took the lives of her mother and brother, Anne Rupp went on dialysis in May 2016, spending three hours a day, three times a week undergoing the blood-cleaning procedure. She hated it.

13 Aug 2018

New drug offers hope to prevent attacks of hereditary angioedema

Hereditary angioedema is a chronic disorder that can sometimes be life-threatening. Now, a new drug therapy has been successfully tested in an international study headed by the University Hospital Frankfurt.

26 Jul 2018

Researchers discover how antibodies secreted in the gut promote growth of healthy microbiome

Researchers at the RIKEN Center for Integrative Medical Science in Japan have discovered how antibodies secreted in the gut promote the growth of beneficial bacteria.

25 Jul 2018

Updated recommendations for HIV prevention and treatment in adults

The International Antiviral Society-USA Panel has released updated recommendations for the treatment and prevention of HIV infection in adults, published in the Journal of the American Medical Association. Michael Saag, M.D., director of the University of Alabama at Birmingham's Center for AIDS Research, served as the article's lead author.

24 Jul 2018

Studies highlight issues regarding black lung, opioid overdose, police violence and more

This study found the national prevalence of coal worker's pneumoconiosis (black lung) is increasing among working coal miners. In central Appalachia, 20.6 percent of miners working more than 25 years have black lung disease.

20 Jul 2018

High-fat diet and systemic inflammation contribute to progression of prostate cancer

Osaka University-led study shows how a high-fat diet and systemic inflammation contribute to prostate cancer progression

18 Jul 2018