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Epigenetic flexibility helps embryos avoid developmental errors

An international research team led by Helmholtz Munich has, for the first time, provided a detailed insight into how the spatial organization of genetic material is established in the cell nucleus of early embryos within the first hours after fertilization.

23 Apr 2025

New approach targets cell surface protein to treat leukemia and solid tumors

In 2021, research led by Ryan Flynn, MD, PhD, and his mentor, Nobel laureate Carolyn Bertozzi, PhD, opened a new chapter in biology, characterizing a new kind of player on the cell surface: glycoRNAs.

23 Apr 2025

New recommendations for the treatment of familial Mediterranean fever

In 2016, EULAR - The European Alliance of Associations for Rheumatology - published recommendations on the treatment of familial Mediterranean fever (FMF). Since then, new evidence has become available, so the recommendations have been reviewed and updated.

23 Apr 2025

DT-109 shows promise in treating atherosclerosis and liver disease

A drug candidate, previously successful at treating severe fatty liver disease, reduces atherosclerosis - a primary driver of cardiovascular death worldwide - in large mammals, a study suggests.

23 Apr 2025

UQ plays key role in a national effort to revolutionize prostate cancer treatment

The University of Queensland will play a key role in a national effort to revolutionize treatment for men with prostate cancer.

22 Apr 2025

DNA origami structures enable targeted imaging of pancreatic cancer

One of the challenges of fighting pancreatic cancer is finding ways to penetrate the organ's dense tissue to define the margins between malignant and normal tissue.

22 Apr 2025

China's malaria-free status offers key lessons for global efforts

China's success in achieving malaria-free status in 2021 offers crucial lessons for the global malaria fight, say experts in a special collection of articles published by The BMJ today.

22 Apr 2025

Study reveals the rising popularity of Tusi in NYC nightclubs

"Tusi", also known as "tucibí" or "pink cocaine", is a drug concoction that emerged in Latin America and Europe within the past decade and is becoming increasingly popular in the USA.

21 Apr 2025

Reversing adipose tissue fibrosis through targeted microRNA therapies

A new review published in Genes & Diseases highlights the transformative role of microRNAs (miRNAs) in regulating and potentially reversing adipose tissue fibrosis, a condition closely linked to obesity, diabetes, and cardiovascular disease.

20 Apr 2025

Small peptides play big role in halting bacterial translation

Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal cellular functions.

18 Apr 2025

The dual role of microRNAs in lung cancer progression and suppression

Lung cancer (LC) is a major global health issue, with high mortality rates and limited therapeutic options. It is primarily categorized into non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC).

18 Apr 2025

Soft brainstem implant offers new hope for restoring hearing

Over the last couple of decades, many people have regained hearing functionality with the most successful neurotech device to date: the cochlear implant.

18 Apr 2025

Novel strategy for treating acute myelogenous leukemia identified

A Ludwig Cancer Research study has identified a novel strategy for treating acute myelogenous leukemia (AML), an aggressive blood cancer for which the median survival time following diagnosis remains just 8.5 months.

16 Apr 2025

Early detection of Alzheimer's disease through blood biomarker

Individuals with a genetic predisposition to Alzheimer's disease show altered blood levels indicating damaged neuronal contacts as early as 11 years before the expected onset of dementia symptoms.

16 Apr 2025

Mid afternoon inhaler use may improve nighttime asthma control

A single daily preventer dose of inhaled corticosteroid (beclomethasone), taken mid afternoon, may be the best timing for effective asthma control as it suppresses the usual nocturnal worsening of symptoms more effectively than dosing regimens at other times of the day, suggest the results of a small clinical trial published in the journal Thorax.

15 Apr 2025

Blood test detects Parkinson’s years before symptoms appear using RNA markers

A new study identifies a blood-based biomarker that detects pre-symptomatic Parkinson’s disease by measuring the ratio of specific nuclear and mitochondrial transfer RNA fragments. The test outperforms standard clinical tools and may also reflect disease mechanisms related to impaired protein synthesis.

14 Apr 2025

Advancing pulmonary fibrosis treatment through targeted drug delivery

Announcing a new article publication for BIO Integration journal. Pulmonary fibrosis (PF) is a progressive interstitial lung disease characterized by excessive extracellular matrix deposition and tissue scarring, and leading to impaired lung function and respiratory failure.

14 Apr 2025

UQ's new research center aims to improve lives of people living with pain

One of the world's foremost pain experts has highlighted the risks of bypassing established processes for assessing the safety and effectiveness of medicines at the launch of a research center at the University of Queensland.

10 Apr 2025

Largest study of osteoarthritis genetics uncovers new drug targets

Osteoarthritis is the leading cause of disability and chronic pain worldwide, affecting an estimated 595 million people globally.

9 Apr 2025

Study reveals sex differences in bone regeneration

Bone regeneration continues to be a critical challenge in tissue engineering, with unpredictable outcomes often hindering clinical application. Current strategies overlook key factors such as donor differences and biological sex, both of which play a significant role in fracture healing.

9 Apr 2025