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Scientists identify mechanism that makes babies more likely than adults to die from sepsis

An immune mechanism that makes babies more likely than adults to die from sepsis has been identified by scientists affiliated with the Center for Research on Inflammatory Diseases in Ribeirão Preto, São Paulo State (Brazil).

4 Jul 2019

Researcher finds possible strategy for killing cancer cells in children

In Belgium, there are 70,000 new adult cases of cancer every year, compared to 350 in children. Owing to lack of interest from pharmaceutical groups, treatments for pediatric cancers are developing much less rapidly than those for adults.

4 Jul 2019

Targeted treatment offers symptom relief for patients with psychosis

Treatment for individuals who experience psychosis, such as hallucinations and delusions as a result of a psychiatric illness, can be targeted to a specific structural mutation, according to a study published by researchers from McLean Hospital and other institutions in the journal Biological Psychiatry.

3 Jul 2019

Asynt's DrySyn OCTO Mini reaction helps optimize biocatalytic hydrogenation

The DrySyn OCTO Mini reaction station from Asynt is enabling researchers to optimise and expand the applications of HydRegen - an innovative, heterogeneous biocatalytic hydrogenation technology currently under development within the group of Prof. Kylie Vincent at the University of Oxford (UK).

From Asynt 3 Jul 2019

Dundee and Bukwang Pharm announce partnership to develop new drug for Parkinson's

The University of Dundee's Drug Discovery Unit has announced a multi-million-pound partnership with Korea-based Bukwang Pharmaceutical Company in a bid to develop a new drug treatment for Parkinson's disease.

3 Jul 2019

Research reveals key cellular mechanism leading to aggressive prostate cancer

Prostate cancer represents a major health challenge and there is currently no effective treatment once it has advanced to the aggressive, metastatic stage.

3 Jul 2019

Pesticide exposure may increase risk of depression in adolescents

Adolescents exposed to elevated levels of pesticides are at an increased risk of depression, according to a new study led by Jose R. Suarez-Lopez, MD, PhD, assistant professor in the Department of Family Medicine and Public Health at University of California San Diego School of Medicine.

2 Jul 2019

Scientists discover a new way to kill drug-resistant parasites

Over one billion people, including 880 million children, are infected with intestinal nematode worms, such as roundworms, hookworms and tapeworms, according to the World Health Organization.

2 Jul 2019

'Scissors' component of CRISPR/Cas9 sometimes gets stuck

In biotech these days, CRISPR/Cas9 is a hot topic, because of its utility as a precise gene editing tool. Before humans repurposed it, CRISPR/Cas9 was a sort of internal immune system bacteria use to defend themselves against phages, or viruses that infect bacteria, by slicing up the phages' DNA.

2 Jul 2019

Scientists reveal mechanism of tumor metastasis and tumor-suppressive role of UDP-glucose

Scientists from Dalian Institute of Chemical Physics and Shanghai Institute of Biochemistry and Cell Biology of the Chinese Academy of Sciences revealed that UDP-glucose accelerates SNAI1 mRNA decay and impairs lung cancer metastasis.

27 Jun 2019

A metabolic intermediate in the uronic acid pathway impairs lung cancer metastasis

In a study published online in Nature on June 26, research teams led by Dr. YANG Weiwei at the Institute of Biochemistry and Cell Biology of the Chinese Academy of Sciences and Dr. LI Guohui from the Dalian Institute of Chemical Physics of CAS reported a new function of uridine diphosphate glucose (UDP-glucose), a metabolic intermediate in the uronic acid pathway: It impairs lung cancer metastasis by accelerating SNAI1 mRNA decay.

27 Jun 2019

Cascade aggravates hereditary storage diseases

In rare, hereditary storage diseases such as Sandhoff's disease or Tay-Sachs syndrome, the metabolic waste from accumulating gangliosides cannot be properly disposed of in the nerve cells because important enzymes are missing.

26 Jun 2019

ELISA test performed in 3D-printed pipette tips simplifies process, reduces cost

Scientists have taken a common, yet laborious lab test and redesigned it to be performed in small 3D printed pipette tips used to measure and transfer fluids in the laboratory.

26 Jun 2019

Interaction between antidepressants and opioid pain medication contributes to lesser pain relief

Common antidepressants interact with the opioid pain medication tramadol to make it less effective for pain relief, according to a study from University Hospitals.

26 Jun 2019

Using Light Scattering to Characterize Protein-Nucleic Acid Interactions

Harnessing the interactions between DNA, RNA, and proteins holds much promise for detecting biomarkers, diagnosing disease, and improving cancer-targeting therapeutics. Quantifying these interactions is essential for understanding and controlling their biomolecular mechanisms.

From Waters | Wyatt Technology 26 Jun 2019