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Illumina signs agreement to acquire Pacific Biosciences

Illumina, Inc. and Pacific Biosciences today announced they have signed an agreement for Illumina to acquire Pacific Biosciences at a price of $8.00 per Pacific Biosciences share in an all-cash transaction.

2 Nov 2018

Zinc can protect against oxidative stress when taken along with coffee, tea, and chocolate

Ageing and a low life expectancy are caused, at least partly, by oxidative stress. A team of researchers led by Prof. Dr. Ivana Ivanovi-Burmazovi from the Chair of Bioinorganic Chemistry at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), together with researchers from the USA, have discovered that zinc can activate an organic molecule, helping to protect against oxidative stress.

2 Nov 2018

Antibiotic found in dirt can destroy mutant mycobacteria responsible for TB, study suggests

For decades, doctors have been using antibiotics to fight tuberculosis. And consistently, the microbe responsible for the disease, Mycobacterium tuberculosis, has been fighting back. When confronted with current drugs, such as the antibiotic rifamycin, the bacterium often mutates in ways that make it resistant to the treatment.

1 Nov 2018

New form of therapy may stop or reverse progressive vision loss

A new form of therapy may halt or even reverse a form of progressive vision loss that, until now, has inevitably led to blindness.

1 Nov 2018

Researchers discover new antibiotic compounds

Researchers have identified new compounds that can target bacterial infection, potentially providing an answer to antibiotic resistance.

1 Nov 2018

Phase III CLL14 study evaluating Venclexta plus Gazyva to treat CLL meets its primary endpoint

Genentech, a member of the Roche Group , announced today that the randomized Phase III CLL14 study, which evaluated fixed-duration Venclexta® in combination with Gazyva® in people with previously untreated chronic lymphocytic leukemia and co-existing medical conditions, met its primary endpoint and showed a statistically significant reduction in the risk of disease worsening or death compared to standard-of-care Gazyva plus chlorambucil.

1 Nov 2018

Study outlines how gut bacteria may influence behavior, including movement

A new study puts a fresh spin on what it means to "go with your gut." The findings, published in Nature, suggest that gut bacteria may control movement in fruit flies and identify the neurons involved in this response.

1 Nov 2018

New drug discovery will increase safety of canine sedation and anesthesia

A drug discovery made at the University of Helsinki's Faculty of Veterinary Medicine will increase the safety of animal sedation and anesthesia. Vatinoxan, the pharmacological molecule discovered in the study, reduced the adverse effects of other drugs on the cardiovascular system of canine patients.

31 Oct 2018

Insilico to present its research in AI for drug discovery at BioCentury China HealthCare Summit

Insilico Medicine, a Rockville-based company developing the end-to-end drug discovery pipeline utilizing the next generation artificial intelligence, will present its research in AI for drug discovery at BioCentury China HealthCare Summit in Shanghai, 13-14 of November.

31 Oct 2018

Creating new environment to improve treatment for limbal stem cell deficiency

You've probably seen the late night ads and the onslaught of cosmetic marketing - hyaluronic acid or hyaluronan, touted as the "fountain of youth," the best moisturizer or skin plumper on the market. It turns out, this naturally occurring molecule, with high concentrations in the eyes, is necessary for creating stem cells in the limbus, the border of the cornea and whites of the eye (sclera).

31 Oct 2018

Study shows how machinery within immune system activates T cells to attack cancer

In just a few years, CAR T-cell and other adoptive T-cell therapies have emerged as among the most promising forms of cancer immunotherapy.

31 Oct 2018

Scientists pinpoint TIM-3 protein as next potential target for immunotherapy treatments

Following the 2018 Nobel Prize for Medicine, global attention is now more than ever turned toward the promise of immunotherapy in oncology. An international team’s work has shed new light on a molecule called TIM-3 that might play a key role in the regulation of the immune response.

31 Oct 2018

Researchers deconstruct royal jelly that determines honeybee hierarchy

Katharina Paschinger's father, a conservation chemist in Vienna, was a devoted beekeeper. Paschinger remembers fondly that he would bring royal jelly, an important food for bee larvae, as a gift on visits to her maternal grandmother.

30 Oct 2018

Scientists find ways to block nitration of amino acids to improve cancer immunotherapy

Immunotherapy -- harnessing T-cells to attack cancer cells in the body -- has given hope to patients who endure round after round of treatment, including chemotherapy, to little effect. For all of its promise, however, immunotherapy still benefits only a minority of patients -- a reality driving research in the field for ways to improve the relatively new approach.

30 Oct 2018

Insights into tumor initiation pave way for new skin cancer treatments

Researchers from VIB and KU Leuven uncovered a key vulnerability of melanoma. While studying the role of the melanoma-specific long non-coding RNA SAMMSON in tumor initiation, the researchers found that it boosts protein synthesis in different cellular compartments. Normal cells are alerted by modification in protein synthesis and react to this threat, but only if this process is altered in one compartment at the time.

29 Oct 2018

Study reveals safety, efficacy of brexpiprazole for schizophrenia patients with severe psychotic symptoms

Otsuka Pharmaceutical Co., Ltd. and H. Lundbeck A/S announced study results on the safety and efficacy of brexpiprazole in the treatment of patients with schizophrenia experiencing severe psychotic symptoms during an acute episode. The data will be presented at the upcoming Psych Congress, held in Orlando from October 25-28, 2018.

26 Oct 2018

Turning tumor-promoting fibroblasts against pancreatic cancer

Pancreatic cancer has a grim prognosis. It is usually detected after the disease has spread, and chemotherapy tends to do little to slow the cancer's growth. Even with treatment, most patients live only about six months after they are diagnosed with the disease.

26 Oct 2018

Molecule News and Research

Illumina signs agreement to acquire Pacific Biosciences

Zinc can protect against oxidative stress when taken along with coffee, tea, and chocolate

Antibiotic found in dirt can destroy mutant mycobacteria responsible for TB, study suggests

New form of therapy may stop or reverse progressive vision loss

Researchers discover new antibiotic compounds

Phase III CLL14 study evaluating Venclexta plus Gazyva to treat CLL meets its primary endpoint

Study outlines how gut bacteria may influence behavior, including movement

New drug discovery will increase safety of canine sedation and anesthesia

Insilico to present its research in AI for drug discovery at BioCentury China HealthCare Summit

Creating new environment to improve treatment for limbal stem cell deficiency

Study shows how machinery within immune system activates T cells to attack cancer

Scientists pinpoint TIM-3 protein as next potential target for immunotherapy treatments

Researchers deconstruct royal jelly that determines honeybee hierarchy

Scientists find ways to block nitration of amino acids to improve cancer immunotherapy

Insights into tumor initiation pave way for new skin cancer treatments

Study reveals safety, efficacy of brexpiprazole for schizophrenia patients with severe psychotic symptoms

Turning tumor-promoting fibroblasts against pancreatic cancer

Baby's tears make female mice to reject male sexual advances

Gut microbiota can contribute to type 2 diabetes

Molecular breakthrough may improve prognosis for pancreatic cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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