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Human protein plays key role in transcription and genome integrity

Researchers from the University of Seville and Cabimer discover that the UAP56/DDX39B protein remove DNA-RNA hybrids from the genome

4 Jun 2020

Computational models predict known biomarkers of inherited metabolic diseases

We are all unique. Our health is determined by our inherent genetic differences combined with our lifestyles and the environments in which we live.

4 Jun 2020

Small protein has a large impact on bacterial gene regulation

Meningococci are bacteria that can cause life-threatening meningitis and sepsis. These pathogens use a small protein with a large impact: The RNA-binding protein ProQ is involved in the activation of more than 250 bacterial genes.

4 Jun 2020

Researchers treat TMC1-related deafness with gene therapy

When Wei Hsi (Ariel) Yeh was a young undergraduate student, one of her close friends went from normal hearing to complete deafness in the span of one month.

4 Jun 2020

Genetic variations linked to COVID-19 severity

A new report by researchers from Thailand's Mahidol University and published on the preprint server medRxiv in May 2020 reports that the clinical severity of COVID-19 may be linked to the genetic makeup of the patient in addition to external factors.

3 Jun 2020

Blood group type may affect susceptibility to COVID-19 respiratory failure

A group of over 120 researchers from various institutions across Europe has performed the first genome-wide association study to reveal host genetic factors that may contribute to respiratory failure in cases of coronavirus disease 209 (COVID-19).

3 Jun 2020

New detection platform may help speed up viral diagnosis

The prompt, precise, and massive detection of a virus is the key to combat infectious diseases such as Covid-19.

3 Jun 2020

Sample inactivation may contribute to false-negative rate of SARS-Cov-2

To protect medical laboratory personnel from infection when testing clinical samples for SARS-CoV-2, most laboratories inactivate the virus before testing.

3 Jun 2020

A vectored vaccine candidate against SARS-CoV-2

The current pandemic of COVID-19 is caused by the severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), a betacoronavirus similar to that which caused the SARS-CoV and MERS-CoV earlier. Scientists are pursuing therapeutic drugs and vaccines to counter the relentless spread of the virus, but so far, none has been established to be effective. However, several are in clinical trials in various parts of the world.

2 Jun 2020

Study maps genes essential for metabolic function of two common bacteria

A study in Cell Reports maps genes essential for the metabolic function of M. agalactiae and M. pneumoniae, two common bacteria that infect livestock and humans respectively.

2 Jun 2020

New advance addresses a big challenge with using CRISPR in cancer patients

A mutation unique to certain cancer tumors is a potential homing beacon for safely deploying CRISPR gene editing enzymes to disarm DNA that makes cancer cells resistant to treatment, while ignoring the gene in normal cells where it's critical to healthy function, according to a new study from ChristianaCare's Gene Editing Institute in the journal Molecular Cancer Research.

2 Jun 2020

Study identifies gene that causes eye loss in cavefish

Mexican cavefish spend their entire lives in the dark. With no need for vision, many of them lost functional eyes.

2 Jun 2020

Researchers identify genetic codes of COVID-19 and SARS viruses that may promote their lifecycles

Researchers have identified specific portions of the genetic codes of the COVID-19 and SARS viruses that may promote the viruses' lifecycles. The new technique is researchers' first tool for determining what genetic sequences stored as RNA - DNA's chemical cousin - are more stable.

2 Jun 2020

SARS-CoV-2 started spreading in the United States in January, CDC says

The United States has reported the highest number of infections across the globe, with more than 1.81 million confirmed cases and at least 105,000 deaths. The magnitude of the novel coronavirus spread hints that the virus may have started earlier than previously thought.

2 Jun 2020

New detection platform for rapid diagnosis of infectious diseases

The prompt, precise, and massive detection of a virus is the key to combat infectious diseases such as Covid-19.

1 Jun 2020

Genetic shuffling and evolutionary selection may have led to SARS-CoV-2 emergence

A combination of genetic shuffling and evolutionary selection of near-identical genetic sequences among specific bat and pangolin coronaviruses may have led to the evolution of SARS-CoV-2 and its introduction into humans, a new study suggests.

30 May 2020

University of Freiburg receives 30 million euros for excellent research

The German Research Foundation has approved a new proposal for a collaborative research center under the leadership of the Institute for Experimental Cardiovascular Medicine at the University Heart Centre Freiburg · Bad Krozingen.

30 May 2020

New genetic engineering technique sets the stage for advances in medicine and beyond

From bacteria-made insulin that obviates the use of animal pancreases to a better understanding of infectious diseases and improved treatments, genetic engineering of bacteria has redefined modern medicine. Yet, serious limitations remain that hamper| progress in numerous other areas.

30 May 2020

Researchers design developmental map of sound-sensing structure in mice’s inner ear

A team of researchers has generated a developmental map of a key sound-sensing structure in the mouse inner ear.

30 May 2020

Study sheds light on homologous recombination of DNA strands

As chromosomes go, X and Y make an unlikely pair. The X is large and contains thousands of genes critical for life. The Y, by contrast, is little more than a nub.

29 May 2020