Therapeutics News and Research

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Precision-guided anticancer nanoparticles help enhance treatment of peritoneal tumors

Research carried out at the University of Tartu Faculty of Medicine used nanoparticles for the development of new imaging and treatment methods for peritoneal cancers. Tests showed that precision-guided anticancer nanoparticles have improved efficacy and reduced side effects.

22 Apr 2019

Research uncovers critical RNA processing aberrations in ALS and FTD

Research by a Barrow Neurological Center scientist on mechanisms of dysfunctional RNA processing in ALS and frontal temporal dementia was published in the April issue of Acta Neuropathologica.

21 Apr 2019

Research sheds light on how hepatitis B virus establishes chronic infection

New research sheds light on how a hepatitis B viral protein stimulates the expansion of immune cells that impair antiviral responses, according to a study published April 18 in the open-access journal PLOS Pathogens by Haitao Guo of the Indiana University School of Medicine, Bin Wang and Jiming Zhang of Fudan University, and colleagues.

19 Apr 2019

Scientific breakthrough provides new hope for people living with multiple sclerosis

A scientific breakthrough provides new hope for millions of people living with multiple sclerosis. Researchers at Oregon Health & Science University have developed a compound that stimulates repair of the protective sheath that covers nerve cells in the brain and spinal cord.

19 Apr 2019

Synthetic biologists add analog-to-digital signal processing to genetic circuitry of living cells

Synthetic biologists have added high-precision analog-to-digital signal processing to the genetic circuitry of living cells.

19 Apr 2019

Novel system enables researchers to study bacteria within mini-tissues in a dish

Engineering bacteria to intelligently sense and respond to disease states, from infections to cancer, has become a promising focus of synthetic biology.

19 Apr 2019

Triple negative breast cancer develop resistance to chemotherapy by turning on molecular pathway

Researchers at The University of Texas MD Anderson Cancer Center have discovered that triple negative breast cancer cells can develop resistance to frontline, or neoadjuvant, chemotherapy not by acquiring permanent adaptations, but rather transiently turning on molecular pathways that protect the cells.

19 Apr 2019

Timing of food intake influences molecular clock in the liver of mice

The timing of food intake is a major factor driving the rhythmic expression of most genes in the mouse liver, researchers report April 16 in the journal Cell Reports.

17 Apr 2019

Researchers create new small molecules that may combat equine encephalitis viruses

Viruses without a preventative vaccine or treatment option pose a looming threat. But for viruses in this category that have already been weaponized and are recognized as human biothreats by the Centers for Disease Control and Prevention, it's a race to find a cure.

17 Apr 2019

Three studies show how tumors hijack the immune system to develop radiotherapy resistance

More than a decade ago, radiation oncologists noticed a nifty phenomenon: Sometimes radiation used locally against a tumor could excite the immune system to attack cancer systemically throughout the body.

17 Apr 2019

Researchers identify cause of inherited metabolic disorder

A new study from BC Children's Hospital, the University of British Columbia (UBC) and an international team of researchers published in the New England Journal of Medicine is the first to identify a rarely-seen type of DNA mutation as the cause of an inherited metabolic disorder.

16 Apr 2019

Coagulation factor VIIa prevents bleeds in hemophilia animal models

Hematology researchers have further refined how a treatment currently used on an urgent basis to control bleeding in hemophilia patients holds promise as a preventive treatment as well.

16 Apr 2019

Researchers complete large analysis of new gene fusion responsible for development of cancers

A consortium of researchers led by Georgetown Lombardi Comprehensive Cancer Center investigators have completed the largest analysis of a new gene fusion they believe is responsible for development of a wide spectrum of cancer types.

16 Apr 2019

Researchers uncover cellular resistance mechanisms to BRAF inhibitors in melanoma

Melanoma is one of the most aggressive types of skin cancer, but recent advances in targeted therapies have improved the prognosis for many patients. Unfortunately, for some patients these positive outcomes are not long lasting, due to the development of drug resistance and tumor recurrence.

15 Apr 2019

Unisex, hormone-free contraceptive pill on the horizon

Side effects from hormonal contraceptives are common. That’s why one start-up is developing a hormone-free contraceptive that can be used by both men and women.

12 Apr 2019

Bioengineered healing glove takes another key step toward commercialization

The revolutionary bioengineered healing glove created by researchers at the University of Texas at Arlington Research Institute and the University of Washington has completed another key step on the road toward commercialization.

12 Apr 2019

Ohio researchers investigate racial disparity in non-alcoholic fatty liver disease

Two top researchers at the Ohio University Heritage College of Osteopathic Medicine are working with two other institutions on a federally funded project to investigate why Hispanics are more prone to develop non-alcoholic fatty liver disease.

12 Apr 2019

Researchers discover unique approach to treat some chronic inflammatory diseases

Inflammation is a balanced physiological response -- the body needs it to eliminate invasive organisms and foreign irritants, but excessive inflammation can harm healthy cells, contributing to aging and chronic diseases.

12 Apr 2019

USC researchers report breakthrough to prevent osteonecrosis of the jaw

USC researchers and collaborators report a breakthrough to prevent damage to the jaw, a side effect suffered by some people undergoing treatment for cancer or osteoporosis.

11 Apr 2019

Increased neutrophil lifespan may contribute to intestinal inflammation in HIV-infected individuals

The increased survival of white blood cells called neutrophils is associated with alterations in the intestinal microbiome of HIV-infected individuals, according to a study published April 11 in the open-access journal PLOS Pathogens by Nichole Klatt of the University of Miami, and colleagues.

11 Apr 2019

Therapeutics News and Research

Precision-guided anticancer nanoparticles help enhance treatment of peritoneal tumors

Research uncovers critical RNA processing aberrations in ALS and FTD

Research sheds light on how hepatitis B virus establishes chronic infection

Scientific breakthrough provides new hope for people living with multiple sclerosis

Synthetic biologists add analog-to-digital signal processing to genetic circuitry of living cells

Novel system enables researchers to study bacteria within mini-tissues in a dish

Triple negative breast cancer develop resistance to chemotherapy by turning on molecular pathway

Timing of food intake influences molecular clock in the liver of mice

Researchers create new small molecules that may combat equine encephalitis viruses

Three studies show how tumors hijack the immune system to develop radiotherapy resistance

Researchers identify cause of inherited metabolic disorder

Coagulation factor VIIa prevents bleeds in hemophilia animal models

Researchers complete large analysis of new gene fusion responsible for development of cancers

Researchers uncover cellular resistance mechanisms to BRAF inhibitors in melanoma

Unisex, hormone-free contraceptive pill on the horizon

Bioengineered healing glove takes another key step toward commercialization

Ohio researchers investigate racial disparity in non-alcoholic fatty liver disease

Researchers discover unique approach to treat some chronic inflammatory diseases

USC researchers report breakthrough to prevent osteonecrosis of the jaw

Increased neutrophil lifespan may contribute to intestinal inflammation in HIV-infected individuals

Advancing therapeutic biopolymer development eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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