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For older adults, smelling the roses may be more difficult

The reports from covid-19 patients are disconcerting. Only a few hours before, they were enjoying a cup of pungent coffee or the fragrance of flowers in a garden. Then, as if a switch had been flipped, those smells disappeared.

1 Dec 2021

Introducing the PhysioMimix™ OOC Multi-Organ Microphysiological System

CN Bio, a leading developer of single and multi-organ microphysiological systems (MPS), otherwise known as organ-on-a-chip (OOC), today announced the commercial launch of its new PhysioMimix™ OOC Multi-Organ MPS.

From CN Bio 1 Dec 2021

Unvaccinated white evangelicals seem to be resistant to persuasive pro-vaccine messages

White evangelical Christians have resisted getting vaccinated against COVID-19 at higher rates than other religious groups in the United States. A new study by Yale researchers provides evidence that persuading these vaccine holdouts to get their shots has only gotten more difficult.

30 Nov 2021

Nanoengineers develop a new approach to effectively deliver mRNA into cells

Nanoengineers at the University of California San Diego have developed a new and potentially more effective way to deliver messenger RNA (mRNA) into cells.

30 Nov 2021

Study compares NAbs from natural SARS-CoV-2 infection vs. vaccine induced against symptomatic infection

Scientists have recently compared the levels of antibody concentrations in unvaccinated, SARS-CoV-2 convalescent individuals and COVID-19 specific antibodies in vaccinated individuals.

30 Nov 2021

New method can precisely, rapidly correct genetic alterations in patient cells

Researchers in the University of Helsinki and University Hospital Helsinki have developed a method to precisely and rapidly correct genetic alterations in the cultured patient cells.

30 Nov 2021

An antiviral regimen based on biomimetic polymers for COVID-19

In a new study published on the bioRxiv* preprint server, scientists proposed the aforementioned mechanism of action (MOA) and have validated it using electron photomicrographs of murine cytomegalovirus (MCMV), which were incubated with a nanoviricide.

30 Nov 2021

Longer between-dose intervals for COVID-19 vaccines may significantly reduce mortality

A recent study, currently available on the medRxiv* preprint server, has shown how longer dosing intervals of vaccines against coronavirus disease (COVID-19) may be able to minimize mortality in low- and middle-income countries in the WHO European region – and significantly change our vaccination strategy.

30 Nov 2021

Study uncovers major disparities in preferred HIV medication uptake in low- and middle-income countries

A new study uncovered large and persistent disparities by sex and age in the uptake of a preferred HIV medication in low- and middle-income countries, potentially subjecting some women to worse HIV treatment outcomes if the situation is not corrected quickly.

30 Nov 2021

Teriflunomide tempers lesion growth in pediatric patients with multiple sclerosis

There are few treatment options for children with multiple sclerosis - a condition in which the immune system attacks the protective covering of nerves in the brain and spinal cord - and most therapies for the disease have not been tested in children.

30 Nov 2021

Scientists develop a smartwatch-based device for early detection of COVID-19

Scientists have developed a wearable device that can detect the early onset of COVID-19 in real-time by analyzing the aberrant changes in physiological parameters caused by SARS-CoV-2 infection.

30 Nov 2021

UK study finds COVID-19 from Delta and Alpha infections are clinically similar

Research suggests that COVID-19 from Delta or Alpha infections is clinically similar, yet Delta is more transmissible than Alpha.

30 Nov 2021

New method helps correct genetic alterations in the cultured patient cells rapidly

Researchers in the University of Helsinki and University Hospital Helsinki have developed a method to precisely and rapidly correct genetic alterations in the cultured patient cells.

30 Nov 2021

Anti-SARS-CoV-2 antibodies suggested to be safe to use in pregnancy

Pregnant patients with mild to moderate COVID-19 were treated with MAb and reported no adverse effects.

30 Nov 2021

Increased illness burden of COVID-19 among unvaccinated first responders

A new study gathered data from the HEROES-RECOVER prospective cohorts and reported an increased illness burden of COVID-19 among unvaccinated first responders.

30 Nov 2021

COVID-19 vaccination coverage and breakthrough infections in urban slums of India

A new study aimed to identify COVID-19 vaccination coverage, examine the factors responsible for COVID-19 vaccination coverage and vaccine hesitancy, study adverse events following immunization patterns after COVID-19 vaccination and determine the prevalence of breakthrough infection after COVID-19 vaccination.

30 Nov 2021

Study on molnupiravir precursor NHC antiviral activity against SARS-CoV-2 variants of concern

In a new study, published on the bioRxiv* preprint server, scientists aimed to determine the reaction of the molnupiravir parent drug (NHC) to different SARS-CoV-2 Variants of Concern (VoCs). They also sought to establish the therapeutic window in a human lung cell model.

29 Nov 2021

Study analyzes the resistance of H. pylori bacterium to antibiotics

A UPV/EHU study analyses the resistance of the Helicobacter pylori (H. pylori) bacterium to the antibiotics routinely used to treat the infection caused by this bacterium.

29 Nov 2021

$Phase I trial evaluates safety, efficacy of astatine for use in alpha therapy for refractory thyroid cancer patients$

Phase I trial evaluates safety, efficacy of astatine for use in alpha therapy for refractory thyroid cancer patients

A research team from the Graduate School of Medicine at Osaka University has started an investigator-initiated clinical trial of sodium astatine ([211At]NaAt) injection for refractory differentiated thyroid cancer patients.

29 Nov 2021

Extended host range for SARS-CoV-2 variants of concern

Researchers used viral pseudotyping to examine whether variants of concern had different host ACE2 receptor usage patterns.

29 Nov 2021

Efficacy News and Research

For older adults, smelling the roses may be more difficult

Introducing the PhysioMimix™ OOC Multi-Organ Microphysiological System

Unvaccinated white evangelicals seem to be resistant to persuasive pro-vaccine messages

Nanoengineers develop a new approach to effectively deliver mRNA into cells

Study compares NAbs from natural SARS-CoV-2 infection vs. vaccine induced against symptomatic infection

New method can precisely, rapidly correct genetic alterations in patient cells

An antiviral regimen based on biomimetic polymers for COVID-19

Longer between-dose intervals for COVID-19 vaccines may significantly reduce mortality

Study uncovers major disparities in preferred HIV medication uptake in low- and middle-income countries

Teriflunomide tempers lesion growth in pediatric patients with multiple sclerosis

Scientists develop a smartwatch-based device for early detection of COVID-19

UK study finds COVID-19 from Delta and Alpha infections are clinically similar

New method helps correct genetic alterations in the cultured patient cells rapidly

Anti-SARS-CoV-2 antibodies suggested to be safe to use in pregnancy

Increased illness burden of COVID-19 among unvaccinated first responders

COVID-19 vaccination coverage and breakthrough infections in urban slums of India

Study on molnupiravir precursor NHC antiviral activity against SARS-CoV-2 variants of concern

Study analyzes the resistance of H. pylori bacterium to antibiotics

Phase I trial evaluates safety, efficacy of astatine for use in alpha therapy for refractory thyroid cancer patients

Extended host range for SARS-CoV-2 variants of concern

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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