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Study reveals the effect of ancestry on molecular makeup of cancer

Questions about the genealogical imprint of tumors have hovered over cancer research since the completion of the Human Genome Project in 2003.

11 May 2020

Genomic sequences from all over the world help fight SARS-CoV-2

As the COVID-19 pandemic rages across the world, killing hundreds of thousands and infecting over 4.1 million, researchers are racing against time to understand the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The SARS-CoV-2 genome has now been sequenced in many different regions of the world, and researchers are collaborating by sharing information to better understand the make-up and mutations that the virus has undergone.

11 May 2020

Neutralizing SARS-CoV-2 via S protein

A new study published on the preprint server bioRxiv* in May 2020 reports on a method to block severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by destroying its main spike protein, which is responsible for attachment to the host cell membrane.

10 May 2020

Study shows COVID-19 vulnerability is highly dependent on host genetic architecture

A new US study available on the preprint server medRxiv reveals certain genetic variations that are associated with infection susceptibility and diverse clinical presentation of coronavirus disease (COVID-19) – including asymptomatic cases and severe forms of the disease in younger patients.

10 May 2020

Scientists create German COVID-19 OMICS Initiative to accelerate research

How does the new coronavirus (SARS-CoV-2) change its genetic information? What other infections occur in patients with COVID-19? Are there genetic risk factors that favor an infection? Numerous genome researchers are pooling their expertise and sequencing infrastructure to make a scientific contribution to manage the COVID-19 pandemic.

9 May 2020

Researchers discover molecular mechanism that helps HSV1 infect the brain

Herpes simplex virus (HSV1) infections are initiated at mucosal surfaces where the virus infects epithelial cells.

8 May 2020

Genomics Medicine Ireland supports scientists participating in global COVID-19 research efforts

Genomics Medicine Ireland announced this week that it is supporting scientists in Ireland who are participating in global research efforts into COVID-19 coronavirus which has so far killed over 200,000 people across the world.

8 May 2020

Huron Digital Pathology granted US patent for barcoding digital images; image search validation paper published in nature digital medicine

Huron Digital Pathology announced today that it has been granted a US patent for barcoding digital images. The invention forms the basis for Huron’s image search platform.

From Huron Technologies 8 May 2020

Pangolins may be the key to new COVID-19 treatments

Researchers at the Medical University of Vienna, Austria, have made an important discovery about the immune response to coronaviruses in pangolins that could point to new approaches for treating human cases of infection.

8 May 2020

Scientists discover fungus that blocks malaria transmission from mosquitoes to people

A fungus that lives in malaria-carrying mosquitoes could boost global efforts to control the disease, which kills about half a million people — mostly children under five — every year.

7 May 2020

DFG to set up new clinical and research units

The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) is setting up three new Research Units and one new Clinical Research Unit.

7 May 2020

Researchers shed new light on the structure of RNA

Australian and US researchers have made a breakthrough in understanding the structure of a key genetic molecule, called RNA, and revealing for the first time how these changes impact RNA's function.

7 May 2020

SARS-CoV-2 in wastewater and rivers

A new study published on the preprint server medRxiv in May 2020 shows that while the virus causing COVID-19 may be present in wastewater and rivers, the biological agent is typically devoid of vitality and unable to cause active infection. This should provide some relief to public health authorities in their quest to contain the virus.

6 May 2020

Spillover of more bat coronaviruses likely due to destruction of wildlife habitats

A new study available on the preprint server bioRxiv used phylogenetic analysis to demonstrate how certain groups of bats harbor multiple coronavirus lineages that are not readily transmitted across different bat taxa. However, the researchers caution that another novel human coronavirus outbreak originating from bats is imminent due to the destruction of wildlife habitats.

6 May 2020

Researchers discover gene variants that reduce the risk of glaucoma

An international research collaboration led by researchers from the University of Helsinki and Stanford University has identified rare changes in a gene called ANGPTL7 that lower intraocular pressure and significantly reduce the risk of glaucoma

6 May 2020

Study provides more insight into the initiation and progression of human cancers

Volume 11, Issue 18 of @Oncotarget Clinical implications of chromatin accessibility assessed by ATAC-seq profiling in human cancers especially in a large patient cohort is largely unknown.

6 May 2020

SARS-CoV-2 genome shows mutation hotspots and type-specific distribution

Now, a new study published on the preprint server bioRxiv reports on a large scale analysis of SARS-CoV-2 genomes and reveals a clonal geo-distribution and rich genetic variations.

5 May 2020

COVID-19 infection risk and outcomes explained by the cell receptor genetic variability

Genetic variants in the angiotensin‐converting enzyme 2 (ACE2) receptor, utilized by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) for cell entry, are predicted to either encourage or inhibit interaction with viral proteins and subsequently contribute to genetic risk in coronavirus disease (COVID-19). This is the key finding of a new study available on the preprint server bioRxiv*.

5 May 2020

Russian scientists create humanized mice to test drugs and vaccines for COVID-19

Following the recent Coronavirus outbreak, almost three million people have been infected worldwide, whereas the death toll has already passed the 200,000 mark, according to official reports.

5 May 2020

Scientists are exploring to find the 'Achilles heel' of coronavirus

Coronavirus, or more exactly SARS-CoV-2, has the world in its grip. How does the virus manage to bind to cells in the human body? How does it gain entry to the cell? How does it hijack the cell's machinery to make it help to replicate the viral genome?

5 May 2020

Genome News and Research

Study reveals the effect of ancestry on molecular makeup of cancer

Genomic sequences from all over the world help fight SARS-CoV-2

Neutralizing SARS-CoV-2 via S protein

Study shows COVID-19 vulnerability is highly dependent on host genetic architecture

Scientists create German COVID-19 OMICS Initiative to accelerate research

Researchers discover molecular mechanism that helps HSV1 infect the brain

Genomics Medicine Ireland supports scientists participating in global COVID-19 research efforts

Huron Digital Pathology granted US patent for barcoding digital images; image search validation paper published in nature digital medicine

Pangolins may be the key to new COVID-19 treatments

Scientists discover fungus that blocks malaria transmission from mosquitoes to people

DFG to set up new clinical and research units

Researchers shed new light on the structure of RNA

SARS-CoV-2 in wastewater and rivers

Spillover of more bat coronaviruses likely due to destruction of wildlife habitats

Researchers discover gene variants that reduce the risk of glaucoma

Study provides more insight into the initiation and progression of human cancers

SARS-CoV-2 genome shows mutation hotspots and type-specific distribution

COVID-19 infection risk and outcomes explained by the cell receptor genetic variability

Russian scientists create humanized mice to test drugs and vaccines for COVID-19

Scientists are exploring to find the 'Achilles heel' of coronavirus

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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