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Spike-based DNA vaccine shows excellent protection against SARS-CoV-2 in a hamster model

A study conducted at the United States Army Research Institute of Infectious Diseases shows how a relatively simple full-length DNA vaccine against spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can elicit neutralizing antibody response in an animal model – even after a single shot with simple jet injection technique.

11 Nov 2020

Researchers link balance dysfunction after traumatic brain injury with diminished sensory acuity

Kessler Foundation researchers have linked balance dysfunction in individuals with traumatic brain injury with diminished sensory acuity.

11 Nov 2020

Research reveals uncertainty in how to care for patients with certain type of heart attack

There are several different types of heart attacks, which occur when blood flow to the heart is blocked or reduced. New research by investigators at Massachusetts General Hospital reveals considerable uncertainty in how to care for patients with one type.

11 Nov 2020

MU researcher develops procedures for defining the preclinical stages of Alzheimer's disease

Both of Andrew Kiselica's grandfathers developed dementia when he was in graduate school. As Kiselica was going through neuropsychology training in graduate school, he saw his mother's father become unable to walk or speak due to severe dementia.

11 Nov 2020

Rheumatoid arthritis may increase risk of dying from COVID-19

Researchers in New Zealand and Australia have conducted a study showing that people with rheumatoid arthritis may be at an increased risk of death if they develop coronavirus disease 2019 (COVID-19) after becoming infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

11 Nov 2020

Children's sleep behaviors linked to gray matter volume with implications for academic performance, IQ

Children who sleep better (that is, those who wake up less during night) and those who wake up earlier have more grey matter in their brains (specifically, in eight cortical regions and in the hippocampus), perform better academically, and have a higher level of intelligence (IQ).

11 Nov 2020

Research tracks humoral immunity response over eight months post COVID-19 infection

Researchers from Chongqing Medical University have tried to answer one of the burning questions regarding the longevity of immune response to coronavirus disease 2019 (COVID-19): How long does immunity last after infection? Their study looked at the lasting effects and continued immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) over eight months after recovery from the infection.

11 Nov 2020

Nafamostat mesylate initially reduces SARS-CoV-2 viral loads in hamsters, study finds

Researchers have found that nafamostat mesylate, when injected in the nasal cavity of Syrian hamsters, can decrease initial SARS-CoV-2 viral loads in their nose. However, this effect was temporary and further testing is required to determine clinically significant effects. The research group's findings are available on the preprint server bioRxiv*.

11 Nov 2020

Experts publish Consensus Statement on management of osteoporosis in patients with CKD G4–G5D

Patients with advanced chronic kidney disease (CKD) suffer from impaired bone quality and quantity, with a non-vertebral fracture risk which is 4-to 6-fold higher than the fracture risk of matched controls.

11 Nov 2020

Daylight exposure can disinfect a special type of cotton face mask

During the COVID-19 pandemic, many people have become accustomed to wearing cotton face masks in public places.

11 Nov 2020

Severe obstructive sleep apnea linked to increased risk of dementia

A new study by Monash University has found that obstructive sleep apnea (OSA) has been linked to an increased risk of dementia.

11 Nov 2020

Team sport improves blood pressure, vascular function in postmenopausal women

Team sport effectively counteracts diminished vascular function in women with high blood pressure, even several years after the onset of menopause.

11 Nov 2020

Study: Retired professional athletes may not suffer more severe cognitive impairment than others

Even though repeated hits to the head are common in professional sports, the long-term effects of concussions are still poorly understood.

11 Nov 2020

Compounds block stress-enhanced reacquisition of nicotine in rats

Stress is a major cause of relapse after people quit smoking. Worrying situations, such as money or relationship problems, can affect neurotransmitter levels in the brain, leading former smokers to reach for a cigarette.

11 Nov 2020

IU researcher awarded NCI grant to develop a drug for making radiation therapy more effective

An Indiana University Melvin and Bren Simon Comprehensive Cancer Center researcher has been awarded a five-year, $2.9 million grant from the National Cancer Institute to develop a drug that could make radiation therapy far more effective.

11 Nov 2020

New study highlights the burden of post-COVID fatigue

More than half of people with acute COVID-19 infection continue to have persistent fatigue 10 weeks after their initial illness, according to a new study published November 9 in the open-access journal PLOS ONE by Liam Townsend of Trinity College Dublin, Ireland and colleagues.

11 Nov 2020

Grants give military veterans better access to cancer clinical trials

SWOG Cancer Research Network and its charity, The Hope Foundation for Cancer Research, announce the award of two grants designed to give military veterans better access to cancer clinical trials.

11 Nov 2020

Five important questions about Pfizer’s COVID-19 vaccine

Pfizer's announcement on Monday that its COVID-19 shot appears to keep nine in 10 people from getting the disease sent its stock price rocketing. Many news reports described the vaccine as if it were our deliverance from the pandemic, even though few details were released.

11 Nov 2020

Researchers identify new prognostic markers for colon cancer

The gut-associated lymphoid tissue represents an integral part of the immune system. Among the powerful players of the mucosa-associated lymphoid tissue are isolated lymphoid structures (ILSs).

11 Nov 2020

Microbes in the lungs could influence lung cancer progression and prognosis

Bottom Line: Enrichment of the lungs with oral commensal microbes was associated with advanced stage disease, worse prognosis, and tumor progression in patients with lung cancer.

11 Nov 2020

Research News and Research

Spike-based DNA vaccine shows excellent protection against SARS-CoV-2 in a hamster model

Researchers link balance dysfunction after traumatic brain injury with diminished sensory acuity

Research reveals uncertainty in how to care for patients with certain type of heart attack

MU researcher develops procedures for defining the preclinical stages of Alzheimer's disease

Rheumatoid arthritis may increase risk of dying from COVID-19

Children's sleep behaviors linked to gray matter volume with implications for academic performance, IQ

Research tracks humoral immunity response over eight months post COVID-19 infection

Nafamostat mesylate initially reduces SARS-CoV-2 viral loads in hamsters, study finds

Experts publish Consensus Statement on management of osteoporosis in patients with CKD G4–G5D

Daylight exposure can disinfect a special type of cotton face mask

Severe obstructive sleep apnea linked to increased risk of dementia

Team sport improves blood pressure, vascular function in postmenopausal women

Study: Retired professional athletes may not suffer more severe cognitive impairment than others

Compounds block stress-enhanced reacquisition of nicotine in rats

IU researcher awarded NCI grant to develop a drug for making radiation therapy more effective

New study highlights the burden of post-COVID fatigue

Grants give military veterans better access to cancer clinical trials

Five important questions about Pfizer’s COVID-19 vaccine

Researchers identify new prognostic markers for colon cancer

Microbes in the lungs could influence lung cancer progression and prognosis

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