Therapeutics News and Research

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Non-coding genetic variant plays key role in endothelial function and disease incidence

Atherosclerotic disease, the slow and silent hardening and narrowing of the arteries, is a leading cause of mortality worldwide. It is responsible for more than 15 million deaths each year, including an estimated 610,000 people in the United States.

15 Nov 2018

Scientists try to develop portable systems that can quickly produce biologics on demand

Many life-saving medicines, including insulin, antibodies and vaccines, are derived from living cells. These "biologics" can be difficult to obtain and store on the battlefield or in remote areas.

15 Nov 2018

Researchers discover molecular basis for therapeutic actions of an African folk medicine

Researchers in the Department of Physiology & Biophysics at the University of California, Irvine School of Medicine have discovered the molecular basis for therapeutic actions of an African folk medicine used to treat a variety of illnesses and disorders including diabetes, pain, headaches, paralysis and epilepsy.

15 Nov 2018

Two genomic tests help identify most effective treatment for breast cancer patients

New results from a long-running trial to identify which new drugs or combinations of drugs are most effective in which types of breast cancer, show that two genomic tests are bringing the era of truly personalized medicine ever nearer.

14 Nov 2018

Enable Injections enters into development agreements with UCB and Apellis Pharmaceuticals

Enable Injections, Inc., a patient-centric drug delivery combination product company developing advanced wearable devices for subcutaneous delivery of high-volume therapeutics, today announced it has entered into development agreements with Apellis Pharmaceuticals, and most recently, UCB.

14 Nov 2018

New anti-HER2 drug shows promising anti-tumor activity in gullet, stomach and bowel cancers

An antibody that binds simultaneously to two distinct regions of the HER2 receptor to block the growth of cancer cells has shown promising signs of anti-tumor activity in a number of cancers including those of the gullet (esophagus), stomach and bowel.

14 Nov 2018

Researchers unravel mystery of NPM1 protein in acute myeloid leukemia

While it has long been recognized that mutated gene NPM1 plays an important role in acute myeloid leukemia, no one has determined how the normal and the mutated forms of the protein NPM1 function.

13 Nov 2018

NIH awards $3.5 million to continue development of robotic system for treating brain tumors

Researchers at Worcester Polytechnic Institute and Albany Medical College, along with corporate partners GE Global Research and Acoustic MedSystems Inc., have received a five-year, $3.5 million award from the National Institutes of Health through the National Cancer Institutes' Academic-Industrial Partnership program, to continue development of an innovative robotic system that, operating within an MRI scanner, can deliver a minimally invasive probe into the brain to destroy metastatic brain tumors with high-intensity therapeutic ultrasound under real-time guidance.

13 Nov 2018

Maverick immune cells can act independently to identify and kill cancer cells, finds research

Immune cells called Gamma Delta T cells can act independently to identify and kill cancer cells, defying the conventional view of the immune system, reveals new research from the Francis Crick Institute and King's College London.

12 Nov 2018

The Human Mini Heart-in-a-Jar That Could One Day Replace Animal Testing

An interview with Dr. Kevin Costa, discussing the miniaturized heart-in-a-jar model developed by Novoheart, and its applications in personalized medicine.

12 Nov 2018

Multidisciplinaryresearch teams selected to study age-related brain disorders

Could our blood hold the molecular secrets to a fountain of youth, preventing age-related brain disorders? Are brain aging and Alzheimer's disease caused by a failure of interconnected systems in our bodies, triggering a domino-like cascade of disease? Can targeting the red blood cells and blood vessels jointly keep our brains healthy and prevent dementia?

12 Nov 2018

New oral drug reduces menstrual bleeding for women with common uterine tumors

A new oral drug significantly reduced menstrual bleeding for women with the most common gynecologic tumors in the United States - benign tumors that disproportionately affect African-Americans, an international clinical trial found.

9 Nov 2018

New single-dose antibiotic effectively treats uncomplicated gonorrhea infections

A phase 2 clinical trial led by Stephanie N. Taylor, MD, Professor of Medicine and Microbiology in the Section of Infectious Diseases at LSU Health New Orleans School of Medicine, has found that a new antibiotic effectively treats uncomplicated urogenital and rectal gonorrhea infections in a single oral dose.

9 Nov 2018

Newer technology with modular dual mobility components lowers risk of dislocation

Hip replacement surgery is highly successful in relieving pain, restoring mobility and improving quality of life. More than 330,000 procedures are performed each year in the United States, and that number is expected to almost double by the year 2030.

8 Nov 2018

Oral antibiotic shows promise to cure uncomplicated gonorrhea

An investigational oral antibiotic called zoliflodacin was well-tolerated and successfully cured most cases of uncomplicated gonorrhea when tested in a Phase 2 multicenter clinical trial, according to findings published today in the New England Journal of Medicine.

8 Nov 2018

New study shows promise of innovative strategy against HER2-driven lung cancers

The HER2 gene is a well-known driver of breast cancer, where changes in this gene are found in about 1-in-5 cases of the disease. HER2 also contributes to about 3 percent of lung cancers, representing about 6,500 patients per year.

8 Nov 2018

Case Western Reserve School of Medicine receives NIH grant for undergraduate cancer research

Case Western Reserve University School of Medicine is preparing and inspiring a new generation of cancer investigators through Cancer-focused Summer Undergraduate Research.

7 Nov 2018

Dietary restriction could help prevent age-related decline in integrity of human gut

Flies eating a Spartan diet are protected from leaky gut and the systemic inflammation associated with it as they age. Conversely, flies on a rich Atkins-like diet are more prone to developing intestinal permeability, a condition linked to a variety of human conditions including inflammatory bowel disease.

5 Nov 2018

US businessman offers $5 million to UTSA College to incubate Alzheimer's challenge

To expand the understanding and explanation of Alzheimer's disease, United States businessman James Truchard has given a $5 million USD gift to The University of Texas at San Antonio College of Sciences to establish the Oskar Fischer Project.

5 Nov 2018

Genetic inhibition of SARM1 prevents axonal degeneration in nervous systems

Disarm Therapeutics, a biotechnology company creating a new class of disease-modifying therapeutics for patients with axonal degeneration, a central driver of neurological disease, today announced data demonstrating that genetic inhibition of SARM1 prevents axonal degeneration in the central, ocular and peripheral nervous systems.

5 Nov 2018

Therapeutics News and Research

Non-coding genetic variant plays key role in endothelial function and disease incidence

Scientists try to develop portable systems that can quickly produce biologics on demand

Researchers discover molecular basis for therapeutic actions of an African folk medicine

Two genomic tests help identify most effective treatment for breast cancer patients

Enable Injections enters into development agreements with UCB and Apellis Pharmaceuticals

New anti-HER2 drug shows promising anti-tumor activity in gullet, stomach and bowel cancers

Researchers unravel mystery of NPM1 protein in acute myeloid leukemia

NIH awards $3.5 million to continue development of robotic system for treating brain tumors

Maverick immune cells can act independently to identify and kill cancer cells, finds research

The Human Mini Heart-in-a-Jar That Could One Day Replace Animal Testing

Multidisciplinaryresearch teams selected to study age-related brain disorders

New oral drug reduces menstrual bleeding for women with common uterine tumors

New single-dose antibiotic effectively treats uncomplicated gonorrhea infections

Newer technology with modular dual mobility components lowers risk of dislocation

Oral antibiotic shows promise to cure uncomplicated gonorrhea

New study shows promise of innovative strategy against HER2-driven lung cancers

Case Western Reserve School of Medicine receives NIH grant for undergraduate cancer research

Dietary restriction could help prevent age-related decline in integrity of human gut

US businessman offers $5 million to UTSA College to incubate Alzheimer's challenge

Genetic inhibition of SARM1 prevents axonal degeneration in nervous systems

Advancing therapeutic biopolymer development eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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