Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

New tool maps how breast cancer grows in previously unseen detail

New technology can trace which populations of breast cancer cells are responsible for the spread of the disease, and for the first time highlights how the location of cancer cells could be as important as mutations in tumor growth.

9 Nov 2022

New insight into how childhood traumas affect health outcomes

The social environments we grow up in are critical when determining our wellbeing and health later in life. Most Americans (67%) report experiencing at least one traumatic event in childhood, and a new study shows that these experiences have significant impacts on our health risks as adults.

8 Nov 2022

Study identifies novel inhibitors against SARS-CoV-2 main protease

In a recent study posted to the bioRxiv* server, researchers at the University of Arizona screened ~11 million severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (MPro)-inhibiting small compounds in the ZINC15 database using a structure-based in-silico screening method.

8 Nov 2022

Accelerating Scientific Discoveries through Advanced Data Analysis Platforms

In this interview, we speak to Victor Wong, Chief Scientific Officer at Core Life Analytics, about their StratoMineRTM product and how it helps researchers to rapidly process their data.

From Core Life Analytics 3 Nov 2022

Vaccination with senescent cells could be a possible therapy against cancer

Cancer cells have a series of features that allow the immune system to identify and attack them. However, these same cells create an environment that blocks immune cells and protects the tumor.

3 Nov 2022

Researchers identify new therapeutic approach against treatment-resistant prostate cancer

Investigators from Cedars-Sinai Cancer have identified an investigational therapeutic approach that could be effective against treatment-resistant prostate cancer. Results of their Phase II clinical trial, published in the peer-reviewed journal Molecular Therapy, have led to a larger, multicenter trial that will soon be underway.

2 Nov 2022

Scientists computationally restore the potency of an antibody against SARS-CoV-2 Omicron subvariants

A team of researchers from the United States computationally modified the COV2-2130 monoclonal antibody to restore its neutralizing ability against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariants, while retaining efficacy against the Delta and wild-type strains.

27 Oct 2022

Bioinformatics analysis of monkeypox virus-host cell interactions

A recent study posted to the bioRxiv* preprint server reported the interaction between monkeypox and human cells. Molecular sequences were screened to identify differentially expressed genes (DEGs) and their associated signal pathway, expression regulation, and metabolic pathways.

18 Oct 2022

BU researcher awarded $4.6 million U2C grant to develop innovative lung cancer biomarkers

Lung cancer screening by chest computed tomography (CT) can detect lung cancer earlier and make the disease less deadly; but even among nodules that are at intermediate risk, only a small minority are cancerous.

17 Oct 2022

Scientists identify group of genes shared between COVID-19 and diabetic kidney disease

Scientists identified five hub genes that might be associated with severe COVID-19 outcomes in patients with diabetic kidney disease.

17 Oct 2022

Mic60-low gene signature may be a simple tool to estimate pancreatic cancer risk

The mitochondria is a key energy-producing component of the human cell that plays an important role in cancer cell metabolism.

12 Oct 2022

Two new studies help improve the understanding of ovarian cancer

Two new discoveries led by Cedars-Sinai Cancer investigators help improve the understanding of what drives the development of ovarian cancer and why some women's tumors do not respond to therapy.

11 Oct 2022

Viagra and Cialis may not be suitable candidates for treating dementia, NIH DREAM study shows

Results from the National Institutes of Health's Drug Repurposing for Effective Alzheimer's Medicines (DREAM) study show that sildenafil (Viagra) and tadalafil (Cialis) may not be suitable candidates for treating dementia.

4 Oct 2022

Artificial intelligence used to predict hospitalization outcomes of geriatric patients with dementia

By using artificial intelligence, Houston Methodist researchers are able to predict hospitalization outcomes of geriatric patients with dementia on the first or second day of hospital admission.

29 Sep 2022

Scientists visualize antibiotics in action inside a pathogenic bacterium

Every living cell relies on proteins in order to function and the process of protein synthesis – translation – is critical for survival.

28 Sep 2022

CDC awards five state public health departments to establish the Pathogen Genomics Centers of Excellence network

Today, CDC announced 5-year awards to five state public health departments. The awards will establish the Pathogen Genomics Centers of Excellence network.

27 Sep 2022

New machine learning tool discovers mutational signature that links bladder cancer to tobacco smoking

Researchers at the University of California San Diego have for the first time discovered a pattern of DNA mutations that links bladder cancer to tobacco smoking.

27 Sep 2022

AI-based drug screening process could speed up the development of life-saving medicines

Developing life-saving medicines can take billions of dollars and decades of time, but University of Central Florida researchers are aiming to speed up this process with a new artificial intelligence-based drug screening process they've developed.

22 Sep 2022

What are the effects of pesticides on neonates' health?

A new study explores the impact of pesticide exposure in neonates, reviewing current literature while evaluating the research methods used in this area.

20 Sep 2022

Crested ibis offers clues that could help our bodies to make better drugs

Thank the rare crested ibis for a clue that could someday help our bodies make better drugs.

19 Sep 2022

Bioinformatics News and Research

Further Reading

New tool maps how breast cancer grows in previously unseen detail

New insight into how childhood traumas affect health outcomes

Study identifies novel inhibitors against SARS-CoV-2 main protease

Accelerating Scientific Discoveries through Advanced Data Analysis Platforms

Vaccination with senescent cells could be a possible therapy against cancer

Researchers identify new therapeutic approach against treatment-resistant prostate cancer

Scientists computationally restore the potency of an antibody against SARS-CoV-2 Omicron subvariants

Bioinformatics analysis of monkeypox virus-host cell interactions

BU researcher awarded $4.6 million U2C grant to develop innovative lung cancer biomarkers

Scientists identify group of genes shared between COVID-19 and diabetic kidney disease

Mic60-low gene signature may be a simple tool to estimate pancreatic cancer risk

Two new studies help improve the understanding of ovarian cancer

Viagra and Cialis may not be suitable candidates for treating dementia, NIH DREAM study shows

Artificial intelligence used to predict hospitalization outcomes of geriatric patients with dementia

Scientists visualize antibiotics in action inside a pathogenic bacterium

CDC awards five state public health departments to establish the Pathogen Genomics Centers of Excellence network

New machine learning tool discovers mutational signature that links bladder cancer to tobacco smoking

AI-based drug screening process could speed up the development of life-saving medicines

What are the effects of pesticides on neonates' health?

Crested ibis offers clues that could help our bodies to make better drugs

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