immunity News and Research

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Mercury in your hot dog? Vaccine skeptics face their limits at crucial CDC meeting

Public health officials watched with dread as a panel shaped by the Trump administration took up an agenda to begin dismantling six decades of vaccination development and progress.

19 Sep 2025

$Kennedy’s take on vaccine science fractures cohesive national public health strategies$

Kennedy’s take on vaccine science fractures cohesive national public health strategies

Health and Human Services Secretary Robert F. Kennedy Jr. has had a busy few months. He fired the director of the Centers for Disease Control and Prevention, purged the agency's vaccine advisory committee, and included among the group's new members appointees who espouse anti-vaccine views.

19 Sep 2025

HIV protein Tat found to increase vulnerability to tuberculosis

According to the World Health Organization, tuberculosis accounts for one in three deaths among people living with HIV.

18 Sep 2025

New NIH grant supports development of experimental pediatric HIV vaccine

A multi-institutional team led by Weill Cornell Medicine investigators has been awarded a five-year, $20.8 million grant from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, for advanced preclinical development of a promising experimental HIV vaccine.

18 Sep 2025

Tracking antibodies reveals four distinct COVID-19 vaccine responses

Two healthcare workers get COVID-19 vaccinations on the same day. Both show strong antibody responses initially, but six months later one stays healthy while the other contracts the virus. A new study published in Science Translational Medicine could help explain this difference.

18 Sep 2025

New findings show lymph nodes educate T cells to combat disease

A team of researchers, led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute), explored the cellular and molecular interactions revealing how lymph nodes play a crucial role in the fight against chronic infection and cancer.

17 Sep 2025

Neurons play a key role in reducing lung inflammation in pulmonary fibrosis

Researchers at the University of Calgary studying a lethal lung disease called pulmonary fibrosis have found neurons, which were known to help detect pain, are also critical for reducing harmful lung inflammation that leads to the disease.

16 Sep 2025

Triple negative breast cancer exploits lymph node niches to block immune defense

In almost all solid tumors - i.e. cancers with a solid tissue structure - the detection of tumor cells in the lymph nodes is considered a decisive marker for the progression of the disease.

16 Sep 2025

Novel biotechnical vector integrates viral and synthetic features for targeted cancer therapy

Gene therapy offers the possibility of addressing cancer at its molecular roots by targeting disease-causing genes rather than relying solely on surgery, chemotherapy, or radiotherapy.

16 Sep 2025

Study reveals how centenarians preserve youthful immune defenses

Researchers mapped immune cells from centenarians, their offspring, and younger controls across three cohorts using multi-omics single-cell profiling. They found that centenarians retain leaner helper pools but have enhanced cytotoxic and NK cell programs, along with reinforced NK–T communication networks.

15 Sep 2025

High BMI and obesity may not always increase mortality risk

It is possible to be "fat but fit", new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) suggests.

15 Sep 2025

UCLA team develops engineered antibodies to fight cytomegalovirus infection

A UCLA research team has found a new way to prompt the immune system to kill cells infected with cytomegalovirus (CMV), a life-threatening infection that is particularly deadly in immunocompromised people.

13 Sep 2025

Waning Japanese encephalitis immunity linked to more severe dengue illness

Scientists from Duke-NUS Medical School, in collaboration with researchers in Nepal, have found that waning immunity to Japanese encephalitis virus (JEV) may increase the risk of more severe dengue disease in humans.

13 Sep 2025

Study identifies C1orf122 as prognostic marker in liver cancer

Primary liver cancer is the third leading cause of cancer-related deaths, of which hepatocellular carcinoma (HCC) accounts for approximately 90% of all liver cancer cases.

11 Sep 2025

RAB26 identified as a critical regulator of prostate cancer aggressiveness

Prostate cancer (PCa) is one of the most common malignant tumors in men worldwide. While early detection has improved patient outcomes, effective therapies for advanced disease remain limited.

11 Sep 2025

Antibody cocktail could change the way the world fights influenza

An unusual therapy developed at The Jackson Laboratory (JAX) could change the way the world fights influenza, one of the deadliest infectious diseases.

11 Sep 2025

Targeting telomere damage offers new path to boost cancer immunotherapy

Tumors are stressful places for cancer-fighting immune cells. Low oxygen, high acid levels, and other stressors put strain on mitochondria, the cell's energy factories, leading to T cell exhaustion and poor cancer outcomes.

10 Sep 2025

Mediterranean-style diet benefits maternal health during pregnancy and breastfeeding

A Mediterranean-style diet, rich in fiber, vegetable proteins and healthy fats, benefits maternal health during pregnancy and breastfeeding.

10 Sep 2025

Dengue infection leaves lasting genetic imprint on immunity

Just as a computer's operating system can be rewritten after a major update, dengue infection can 're-programme' the body's immune system, leaving a long-lasting genetic imprint that influences how people respond to future infections-an effect not seen with vaccination.

9 Sep 2025