Immune System News and Research

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Study: Flavoring chemicals of e-cigarette vapor alone can measurably damage the lungs

Known for their appetizing flavors, such as bubblegum, banana and strawberry, e-cigarettes continue to grow in popularity around the world. Promoted by makers as a "healthy" alternative to regular tobacco cigarettes, researchers are finding e-cigarettes, or vaping, still result in injury to the lungs.

15 Dec 2020

FDA approves first IGA in GalSafe pigs for human food, promising therapeutic uses

Today, the U.S. Food and Drug Administration approved a first-of-its-kind intentional genomic alteration (IGA) in a line of domestic pigs, referred to as GalSafe pigs, which may be used for food or human therapeutics.

15 Dec 2020

COVID-19 vaccine shows the long-term value of curiosity-driven basic research

The most promising vaccine against the coronavirus to date is also an example of the long-term value of curiosity-driven basic research and its funding by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation).

15 Dec 2020

Microglial surveillance helps prevent seizure activity in the brain

An important part of the brain's immune system, cells called microglia constantly extend and retract "branches" from their cell body to survey their environment.

14 Dec 2020

ACAAI releases guidance related to risk of allergic reactions to Pfizer-BioNTech COVID-19 vaccine

With the emergency use authorization of the Pfizer-BioNTech COVID-19 vaccine by the FDA on December 11, 2020, and distribution beginning today, the American College of Allergy, Asthma and Immunology COVID-19 Vaccine Task Force recommends the following guidance related to risk of an allergic reaction on vaccination for those who receive the vaccine.

14 Dec 2020

Compound derived from thunder god vine could improve outcomes for pancreatic cancer patients

The results of a pre-clinical study led by researchers at the Translational Genomics Research Institute, an affiliate of City of Hope, suggest how a compound derived from the thunder god vine -- an herb used in China for centuries to treat joint pain, swelling and fever -- is able to kill cancer cells and potentially improve clinical outcomes for patients with pancreatic cancer.

14 Dec 2020

New method shortens the timeline to generate mice for vaccine research

To develop vaccines and investigate human immune responses, scientists rely on a variety of animal models, including mice that can produce human antibodies through genetically engineered B cell receptors, which are specialized antibodies bound to the B cell membrane.

14 Dec 2020

Multisystem immune-related adverse events linked with improved survival from immunotherapy in NSCLC

The results of a large, retrospective study of patients who received a form of immunotherapy for non-small cell lung cancer (NSCLC) revealed that patients may get more than one immune-related side effect, and identified a correlation between these multisystem immune-related adverse events (irAEs) and improved patient survival.

14 Dec 2020

Remdesivir likely to be highly effective treatment for COVID-19

The drug remdesivir is likely to be a highly effective antiviral against SARS-CoV-2, according to a new study by a team of UK scientists.

14 Dec 2020

Recovered COVID-19 patients exhibit persistent cellular immunity

Researchers at The Rockefeller University in New York have conducted a study showing that infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – triggers persistent T cell responses that last for at least six months.

14 Dec 2020

Study identifies protein as potential therapeutic target for leishmaniasis vaccines

According to the results of research led by the Complutense University of Madrid (UCM), one the various strategies deployed by the Leishmania parasite to avoid triggering the human immune system is to activate the SHP-1 protein.

11 Dec 2020

UCLA researchers identify gene that could help predict cervical cancer treatment response

UCLA researchers have identified a potential diagnostic marker that could help predict how likely someone with cervical cancer is to respond to the standard treatment of chemotherapy and radiation.

11 Dec 2020

Research reveals insights into potential drivers of 'wet' age-related macular degeneration

"Wet" age-related macular degeneration (AMD) is one of the most common causes of irreversible vision loss in the elderly, and it occurs when abnormal and leaky blood vessels form in the retina, in part due to inflammation.

11 Dec 2020

Pre-existing immunity shapes a person's antibody response to influenza viruses

New research by scientists at the University of Chicago suggests a person's antibody response to influenza viruses is dramatically shaped by their pre-existing immunity, and that the quality of this response differs in individuals who are vaccinated or naturally infected.

11 Dec 2020

Scientists use human stem cells and bioengineered scaffold to build whole functioning thymus

Researchers at the Francis Crick Institute and University College London have rebuilt a human thymus, an essential organ in the immune system, using human stem cells and a bioengineered scaffold.

11 Dec 2020

New analysis method could pave the way for important breakthroughs in immunotherapy

In a new study, researchers at Uppsala University have been able to show differences in how Rituximab, a monoclonal antibody drug, interacts with the blood of healthy individuals compared to patients with chronic lymphatic leukemia. This has awakened hopes that this analysis method could pave the way for important breakthroughs in immunotherapy research and treatment.

11 Dec 2020

Research shows how epithelial cells ward off viruses

A team led by Ludwig-Maximilians-Universitaet in Munich Researcher Veit Hornung has shown that a protein found in skin cells recognizes a specific nucleic acid intermediate that is formed during virus replication. This recognition process subsequently induces a potent inflammatory response.

11 Dec 2020

Immune System News and Research

Study: Flavoring chemicals of e-cigarette vapor alone can measurably damage the lungs

FDA approves first IGA in GalSafe pigs for human food, promising therapeutic uses

COVID-19 vaccine shows the long-term value of curiosity-driven basic research

Microglial surveillance helps prevent seizure activity in the brain

ACAAI releases guidance related to risk of allergic reactions to Pfizer-BioNTech COVID-19 vaccine

Compound derived from thunder god vine could improve outcomes for pancreatic cancer patients

New method shortens the timeline to generate mice for vaccine research

Multisystem immune-related adverse events linked with improved survival from immunotherapy in NSCLC

Remdesivir likely to be highly effective treatment for COVID-19

Recovered COVID-19 patients exhibit persistent cellular immunity

Study identifies protein as potential therapeutic target for leishmaniasis vaccines

UCLA researchers identify gene that could help predict cervical cancer treatment response

Research reveals insights into potential drivers of 'wet' age-related macular degeneration

Pre-existing immunity shapes a person's antibody response to influenza viruses

Scientists use human stem cells and bioengineered scaffold to build whole functioning thymus

New analysis method could pave the way for important breakthroughs in immunotherapy

Research shows how epithelial cells ward off viruses

AI tool helps clinical labs to rule out COVID-19

First patient participates in immunotherapy trial despite COVID-19 pandemic

Osteoporosis drug also promotes infiltration of immune cells in breast tumors

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