Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Discovery about how cancer cells hide from the immune system could improve treatments

Researchers have shed light on the mechanism through which cancer cells become camouflaged to escape immune system detection and attack.

31 Jan 2020

New treatment target could change the outlook of patients at risk of kidney injury

Kidney injury is a dreaded complication of commonly performed procedures such as coronary angiography or cardiac surgery, often stopping physicians and patients in their tracks.

30 Jan 2020

Avacta demonstrates initial proof-of-concept for TMAC drug conjugates in pre-clinical study

Avacta Group plc, the developer of Affimer biotherapeutics and reagents, is pleased to announce that it has demonstrated initial proof-of-concept for its proprietary new class of drug conjugate, TMAC, in a pre-clinical animal model of cancer.

From Avacta Life Sciences Ltd. 28 Jan 2020

Coronavirus spreads - Australian breakthrough

Novel coronavirus, temporarily named “2019-nCoV”, has affected over 4,600 persons across the world and is spreading at a rapid pace say experts. The World Health Organization and other health organizations have stepped up vigilance to detect and isolate the infection to contain outbreaks.

28 Jan 2020

Clinical trial to test safety, effectiveness of mAb against malaria in healthy volunteers

A Phase 1 clinical trial testing the safety and effectiveness of a monoclonal antibody (mAb) against malaria has begun enrolling healthy adult volunteers at the National Institutes of Health Clinical Center in Bethesda, Maryland. The trial, sponsored by NIH's National Institute of Allergy and Infectious Diseases (NIAID), is the first to test mAb CIS43LS in humans. It aims to enroll up to 73 volunteers aged 18 through 50 years old who have never had malaria.

27 Jan 2020

Marburg virus detected in fruit bats of Sierra Leone

The Marburg virus is a close relative of the Ebola virus explain researchers. It may also lead to the deadly life threatening hemorrhagic disease in patients as seen with Ebola. Until now there have been no reported cases of Marburg infection in Sierra Leone say health officials. The detection in the bats however could signal the risk the local population might be at or getting infected.

26 Jan 2020

Determining Microsatellite Instability Status Using Multiplex PCR-Based Methods

Determining microsatellite instability status using multiplex PCR-based methods used to screen for Lynch Syndrome, a dominant hereditary cancer propensity.

From Promega Corporation 24 Jan 2020

Scientists detect Marburg virus in Sierra Leone fruit bats

Scientists have detected Marburg virus in fruit bats in Sierra Leone, marking the first time the deadly virus has been found in West Africa. Eleven Egyptian rousette fruit bats tested positive for active Marburg virus infection. Research teams caught the bats separately in three health districts.

24 Jan 2020

Carterra closes financing round for continued growth of the LSA platform for next generation antibody discovery

Carterra Inc., the world leader in high-throughput antibody screening and characterization, has closed a $6M round of financing led by Ballast Point Ventures with participation from current investor, Telegraph Hill Partners.

From Carterra Inc. 23 Jan 2020

GW expands clinical trial of neoadjuvant immunotherapy for high-risk cutaneous squamous cell carcinoma

The Cutaneous Oncology Program at the George Washington University (GW) Cancer Center was selected as the first global site for a clinical trial for patients with high-risk cutaneous squamous cell carcinoma.

22 Jan 2020

Scientists reverse HIV latency, take major scientific step toward curative therapies

Approximately 38 million people are infected with HIV worldwide, about 1.1 million people in the United States. Currently, people with HIV take antiretroviral therapy (ART), which can suppress HIV to undetectable levels in blood, but the virus persists throughout the body in latently infected resting CD4+ T cells.

22 Jan 2020

Turbine appoints new SAB members to guide its simulation-first drug discovery mission

Turbine, a simulation-first drug discovery company, today announced the formation of its Scientific Advisory Board with the appointments of Dr. Annalisa Jenkins, Dr. Mihriban Tuna, and Dr. Alan Barge.

21 Jan 2020

Discovery of mechanism by which Zika virus enters brain cells

Two independent studies published by Cell Press on January 16, 2020, report that the mechanism by which Zika virus enters brain cells has been identified and even more, exploited to prevent Zika infection and to kill cancer cells instead.

16 Jan 2020

Genetically engineered mosquitoes halt Dengue spread

A new study published in the journal PLOS Pathogens in January 2020 reports the development of mosquitoes that have been genetically modified to resist infection by several types of the dengue virus. This is the first time ever that all types of the virus have been targeted by the engineering of the mosquito DNA. Covering all virus types is essential to achieve proper disease control.

16 Jan 2020

New method for detection of microcystins and nodularin in human urine

Blooms of toxin-producing algae exploded in both fresh and salt water ecosystems in southern Florida during the summer months of 2018, impacting wildlife and humans living in these marine environments.

16 Jan 2020

B cell count tells how certain cancers will respond to immunotherapy

Some melanomas, sarcomas and renal cell carcinomas, but not all, have been found to respond dramatically to new drugs called immune checkpoint blockers, which exploit the body’s known capability to mount an immune response against the foreign antigen-bearing tumor cells.

15 Jan 2020

Skin-protecting antibody may promote tumor growth during chronic tissue inflammation

One of the skin's defenses against environmental assault can help tumors to grow when skin is exposed to chronic inflammation, finds a study in mice published today in eLife.

14 Jan 2020

Boehringer Ingelheim and Enleofen partner to develop anti-IL-11 therapies for multiple fibrotic disorders

Boehringer Ingelheim and Enleofen Bio Pte. Ltd. announced today the acquisition of worldwide exclusive rights to Enleofen’s preclinical interleukin-11 (IL-11) platform by Boehringer Ingelheim to develop first-in-class therapies across a broad range of fibro-inflammatory diseases.

From Boehringer Ingelheim International GmbH 14 Jan 2020

How SpatialOMx is Delivering New Insights into Disease Research

An interview with Shannon Cornett Ph.D, discussing the use of MALDI-guided spatial molecular analysis for biomarker discovery.

From Bruker Daltonics 14 Jan 2020

Integral Molecular announces panel of P2X7 antibodies for autoimmune disorders

Integral Molecular, the leader in discovering antibodies against multipass membrane proteins, announces lead monoclonal antibodies (MAbs) against P2X7, a structurally complex ion channel that is the target for autoimmune disorders including atopic dermatitis and glomerulonephritis.

10 Jan 2020

Antibody News and Research

Further Reading

Discovery about how cancer cells hide from the immune system could improve treatments

New treatment target could change the outlook of patients at risk of kidney injury

Avacta demonstrates initial proof-of-concept for TMAC drug conjugates in pre-clinical study

Coronavirus spreads - Australian breakthrough

Clinical trial to test safety, effectiveness of mAb against malaria in healthy volunteers

Marburg virus detected in fruit bats of Sierra Leone

Determining Microsatellite Instability Status Using Multiplex PCR-Based Methods

Scientists detect Marburg virus in Sierra Leone fruit bats

Carterra closes financing round for continued growth of the LSA platform for next generation antibody discovery

GW expands clinical trial of neoadjuvant immunotherapy for high-risk cutaneous squamous cell carcinoma

Scientists reverse HIV latency, take major scientific step toward curative therapies

Turbine appoints new SAB members to guide its simulation-first drug discovery mission

Discovery of mechanism by which Zika virus enters brain cells

Genetically engineered mosquitoes halt Dengue spread

New method for detection of microcystins and nodularin in human urine

B cell count tells how certain cancers will respond to immunotherapy

Skin-protecting antibody may promote tumor growth during chronic tissue inflammation

Boehringer Ingelheim and Enleofen partner to develop anti-IL-11 therapies for multiple fibrotic disorders

How SpatialOMx is Delivering New Insights into Disease Research

Integral Molecular announces panel of P2X7 antibodies for autoimmune disorders

How to make hybridoma-based antibody discovery more efficient eBook

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