Immune System News and Research

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Chemicals in e-cigarettes disrupt the gut barrier and trigger inflammation

Touted by makers as a "healthy" alternative to traditional nicotine cigarettes, new research indicates the chemicals found in e-cigarettes disrupt the gut barrier and trigger inflammation in the body, potentially leading to a variety of health concerns.

7 Jan 2021

Antibodies and inflammatory markers are pervasive in colostrum of SARS-CoV-2 infected women

A recent study, currently available on the medRxiv* preprint server, is among the first to reveal the presence of antibodies against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in colostrum and to demonstrate elevated cytokine levels in colostrum from women exposed to the virus.

7 Jan 2021

Researchers provide comprehensive molecular characterization of head and neck cancers

In what is believed to be the most comprehensive molecular characterization to date of the most common type of head and neck cancer, researchers from the Johns Hopkins departments of pathology and oncology, the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins University School of Medicine, and 18 other centers around the U.S. and Poland have clarified the contribution of key cancer-associated genes, proteins and signaling pathways in these cancers, while proposing possible new treatment avenues.

7 Jan 2021

SARS-CoV-2 viral load in saliva may be linked to COVID-19 disease severity

Researchers at Yale University School of Medicine found that SARS-CoV-2 viral loads in saliva are higher for patients with associated risk factors and underlying conditions that lead to severe COVID-19 and death. Thus, saliva viral loads could be used to predict disease severity.

7 Jan 2021

Common gene expression changes at target tissues of four autoimmune diseases found

Autoimmune diseases are diseases of "mistaken identity", where the immune system - which is supposed to protect us against infectious diseases and neoplasias - mistakenly attacks and destroys components of our own body.

7 Jan 2021

Severe COVID-19 recovered patients do not display long-lasting adaptive immune responses, finds study

A team of scientists from the University of Valencia and INCLIVA Health Research Institute, Spain, has recently investigated the durability of immune responses specifically developed against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of coronavirus disease 2019 (COVID-19).

7 Jan 2021

New approach can help identify novel treatments for autoimmune diseases

A team of researchers led by the Indiana Biosciences Research Institute Diabetes Center's Scientific Director Decio L. Eizirik, MD, PhD, has found that identifying new treatments for autoimmune diseases requires studying together the immune system AND target tissues.

7 Jan 2021

Researchers examine the role of Shiga toxin in the immune system

E. coli food poisoning is one of the worst food poisonings, causing bloody diarrhea and kidney damage. But all the carnage might be just an unintended side effect, researchers from UConn Health report in the 27 November issue of Science Immunology.

7 Jan 2021

New peptide can target specific pathogen without damaging the good bacteria

Drug-resistant bacteria could lead to more deaths than cancer by 2050, according to a report commissioned by the United Kingdom in 2014 and jointly supported by the U.K. government and the Wellcome Trust.

7 Jan 2021

Adaptive immune system against COVID-19 can last for at least eight months

New data suggest that nearly all COVID-19 survivors have the immune cells necessary to fight re-infection.

6 Jan 2021

In-silico modeling provides new understanding of immune response to SARS-CoV-2

The COVID-19 pandemic caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has crippled global healthcare systems and triggered an economic crisis in many countries. The pandemic is not showing signs of a slowdown even in 2021 with a new and more infectious variant of the virus wreaking havoc in the UK and many other parts of the world.

6 Jan 2021

Main bioactive compound of ginger root may protect against autoimmune disease progression

Naturopathic medicine, or herbal medicine, is all the rage, especially among young people. But how much of this is supported by science?

6 Jan 2021

Researchers identify the missing link between intestinal disease and brain injury in premature infants

Physicians have long known that necrotizing enterocolitis (NEC), a potentially lethal inflammatory condition that destroys a premature infant's intestinal lining, is often connected to the development of severe brain injury in those infants who survive.

6 Jan 2021

NIAID set to conduct large monoclonal SARS-CoV-2 antibody clinical trial

A large clinical trial, known as the Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV-2), is set to take place, which aims to test monoclonal antibody efficacy and safety in people who have mild or moderate COVID-19.

6 Jan 2021

Vitamin D supplementation found to reduce COVID-19-related mortality, says study

Researchers have shown that prescribing vitamin D supplementation to COVID-19 patients seems to decrease the mortality rate, the severity of the disease, and serum levels of inflammatory markers.

6 Jan 2021

Evidence review: COVID-19 infections are generally 'mild' in children under five years

Babies and asymptomatic cases account for up to half of COVID-19 infections in the under-five age group, which has implications for vaccination programs, a new UNSW study has found.

6 Jan 2021

New mathematical model proposes optimal treatment strategies for COVID-19

Getting control of COVID-19 will take more than widespread vaccination; it will also require a better understanding of why the disease causes no apparent symptoms in some people but leads to rapid multi-organ failure and death in others, as well as better insight into what treatments work best and for which patients.

5 Jan 2021

Researchers reveal distinct molecular signature in tumor tissues of Black breast cancer patients

A Roswell Park Comprehensive Cancer Center team led by Christine Ambrosone, PhD, and Song Yao, PhD, has revealed a distinct molecular signature in the tumor tissues of Black patients with breast cancer.

5 Jan 2021

Research offers clues on why pregnancy may raise risk of organ transplant rejection

A research study at the University of Chicago has found that in pregnancy, while the T cell response to a fetus becomes tolerant to allow for successful pregnancy, the part of the immune system that produces antibodies (known as the humoral response) becomes sensitized, creating memory B cells that can later contribute to the rejection of a transplanted organ.

4 Jan 2021

Sugar-binding protein could promote inflammation and worsen sepsis

A sugar-binding protein could fuel terrible inflammation and worsen sepsis, a disease that kills more than 270,000 people every year in the US alone, reports a team of researchers led by UConn Health in the 4 January issue of Nature Immunology.

4 Jan 2021

Immune System News and Research

Chemicals in e-cigarettes disrupt the gut barrier and trigger inflammation

Antibodies and inflammatory markers are pervasive in colostrum of SARS-CoV-2 infected women

Researchers provide comprehensive molecular characterization of head and neck cancers

SARS-CoV-2 viral load in saliva may be linked to COVID-19 disease severity

Common gene expression changes at target tissues of four autoimmune diseases found

Severe COVID-19 recovered patients do not display long-lasting adaptive immune responses, finds study

New approach can help identify novel treatments for autoimmune diseases

Researchers examine the role of Shiga toxin in the immune system

New peptide can target specific pathogen without damaging the good bacteria

Adaptive immune system against COVID-19 can last for at least eight months

In-silico modeling provides new understanding of immune response to SARS-CoV-2

Main bioactive compound of ginger root may protect against autoimmune disease progression

Researchers identify the missing link between intestinal disease and brain injury in premature infants

NIAID set to conduct large monoclonal SARS-CoV-2 antibody clinical trial

Vitamin D supplementation found to reduce COVID-19-related mortality, says study

Evidence review: COVID-19 infections are generally 'mild' in children under five years

New mathematical model proposes optimal treatment strategies for COVID-19

Researchers reveal distinct molecular signature in tumor tissues of Black breast cancer patients

Research offers clues on why pregnancy may raise risk of organ transplant rejection

Sugar-binding protein could promote inflammation and worsen sepsis

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