Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Adding a specific immune molecule can boost efficacy of rabies vaccine

Every year, more than 59,000 people around the world die of rabies and there remains no cheap and easy vaccine regimen to prevent the disease in humans. Now, researchers report in PLOS Neglected Tropical Diseases that adding a specific immune molecule to a rabies vaccine can boost its efficacy.

From PLOS ONE 11 Nov 2019

Optimal therapy for Down syndrome arthropathy remains unclear, reveals study

A new study found that patients with Down syndrome arthropathy continue to have an approximate year-long delay in diagnosis from the onset of their symptoms, and that optimal therapy for this condition remains unclear.

11 Nov 2019

Atmospheric and environmental changes linked to organ-specific lupus flares

New research findings presented at the 2019 ACR/ARP Annual Meeting found a strong association between changes in atmospheric and environmental variables 10 days before a clinic visit and organ-specific lupus flares in patients with systemic lupus erythematosus.

10 Nov 2019

Study finds fewer new cases of HCV in HIV-negative men who have sex with PrEP-using men

Data from a new study presented this week at The Liver Meeting – held by the American Association for the Study of Liver Diseases – found fewer new cases of hepatitis C infection (commonly called HCV), despite very high rates of other sexually-transmitted infections, in HIV-negative men who have sex with men who take pre-exposure prophylaxis (PrEP) treatments.

10 Nov 2019

Research discovers link between biomarker for RA and industrial air pollutants

New, late-breaking research discovered that there are significant associations between anti-citrullinated protein bodies, a characteristic biomarker for rheumatoid arthritis, and industrial emissions of fine particles matter and sulfur dioxide.

10 Nov 2019

Investigators use the power of computation to build better targeted drug therapy

Antibody drug conjugates (ADCs) -- cancer drugs that are designed to target and destroy cancerous tissue while leaving healthy cells intact -- represent a long sought-after advancement in cancer therapy.

8 Nov 2019

Understanding Monoclonal Antibody Unfolding and Aggregation

A therapeutic monoclonal antibody and its Fab and Fc fragments were recently investigated using differential scanning fluorimetry, temperature-ramped dynamic light scattering, and turbidity measurements.

From Waters | Wyatt Technology 8 Nov 2019

New vaccine strategy shows promise against HIV

A collaborative team of scientists has made a successful proof-of-principle demonstration of an advanced HIV vaccine strategy--an approach that may also work in protecting people from an array of other deadly infectious diseases.

7 Nov 2019

Sphere Fluidics and Peak Analysis and Automation introduce integrated micro-plate handling and single cell analysis capabilities

Sphere Fluidics and Peak Analysis and Automation, announce optimization of the Single Cell Analysis System through integration with automated plate handler.

From Fluidic Sciences and Sphere Bio 7 Nov 2019

HIV-1 virus characteristics can predict treatment efficacy with specific antibody treatment

Current HIV-1 therapies have been proven to be highly effective in slowing the progression of the virus in the body with only minimal side effects.

6 Nov 2019

Study: Pleural effusions are linked with NSCLC and malignant mesothelioma

Cryopreserved cell-free PE fluid from 101 NSCLC patients, 8 mesothelioma and 13 with benign PE was assayed for a panel of 40 cytokines/chemokines using the Luminex system.

6 Nov 2019

UM launches CAR-T clinical trial for patients with myasthenia gravis

Neuromuscular experts with the University of Miami Health System and the Miller School of Medicine will launch a Phase 1/2 clinical trial (NCT04146051) using the CAR-T drug, Descartes-08, to treat patients with generalized myasthenia gravis.

5 Nov 2019

HIMC at Mount Sinai to evaluate therapeutic effects of novel cancer immunotherapy

The Human Immune Monitoring Center at the Icahn School of Medicine at Mount Sinai will apply cutting-edge high-throughput technologies to evaluate the therapeutic effects of Libtayo (cemiplimab-rwlc), a PD-1 antibody blockade developed by biotechnology company Regeneron Pharmaceuticals, Inc and Sanofi.

5 Nov 2019

Sesame allergy is common among children with other food allergies

Investigators at the National Institutes of Health have found that sesame allergy is common among children with other food allergies, occurring in an estimated 17% of this population.

4 Nov 2019

Protein may help predict, prevent and treat brain metastases

A protein that breast, lung and other cancers use to promote their spread--or metastasis--to the brain, has been identified by a team led by Weill Cornell Medicine and New York-Presbyterian investigators. The protein, CEMIP, will now be a focus of efforts to predict, prevent and treat brain metastases, which are a frequent cause of cancer deaths.

4 Nov 2019

Correlates of HIV risk associated with decrease in disease transmission, study confirms

Immune responses that are associated with a decreased risk of infection are called correlates of protection.

1 Nov 2019

Measles resets children’s immune systems to a “baby-like” state

New studies have shown that measles can compromise the immune system’s ability to fight off other future infections.

1 Nov 2019

Study shows how measles virus causes immune amnesia

Over the last decade, evidence has mounted that the measles vaccine protects in not one but two ways: Not only does it prevent the well-known acute illness with spots and fever that frequently sends children to the hospital, but it also appears to protect from other infections over the long term.

31 Oct 2019

DGIST and Ahn-Gook Pharmaceutical sign R&D agreement for development of anti-cancer antibody

A research group, led by Professor Kyungmoo Yea at the Department of New Biology, DGIST has signed an agreement on the joint R&D for the development of anti-cancer antibody with Ahn-Gook Pharmaceutical Co., Ltd. in September.

30 Oct 2019

Atlantic Health System Cancer Care enrolling patients in five pancreatic cancer studies

November is National Pancreatic Cancer Awareness month. This year alone, more than 56,000 Americans will be diagnosed with pancreatic cancer. Pancreatic tumors are particularly aggressive and hard to treat "due to a mutational profile that makes it resistant to therapies that work better for other tumor types," explains Angela Alistar, MD, medical director of GI Oncology at Morristown Medical Center.

30 Oct 2019