Alzheimer's Disease News and Research

RSS

Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

OHSU analysis finds previous studies have overstated effectiveness of bone growth product used in spinal surgeries

An analysis by the Evidence-based Practice Center at Oregon Health & Science University has found that previously published clinical trial studies about a controversial bone growth product used in spinal surgeries overstated the product's effectiveness.

19 Jun 2013

NIH awards $12.7M to research groups to explore new treatments for patients in eight disease areas

The National Institutes of Health has awarded $12.7 million to match nine academic research groups with a selection of pharmaceutical industry compounds to explore new treatments for patients in eight disease areas, including Alzheimer's disease, Duchenne muscular dystrophy and schizophrenia.

19 Jun 2013

Lipidation states in certain proteins in the brain differ depending on genotype, cognitive diseases

The lipidation states (or modifications) in certain proteins in the brain that are related to the development of Alzheimer disease appear to differ depending on genotype and cognitive diseases, and levels of these protein and peptides appear to be influenced by diet, according to a report published Online First by JAMA Neurology, a JAMA Network publication.

19 Jun 2013

Blocking B1R receptor activity in brains of Alzheimer's mice recovers memory and cerebrovascular function

A new study shows that memory pathology in older mice with Alzheimer's disease can be reversed with treatment. The study by researchers from the Montreal Neurological Institute and Hospital - The Neuro, at McGill University and at Universit- de Montr-al found that blocking the activity of a specific receptor in the brain of mice with advanced Alzheimer's disease (AD) recovers memory and cerebrovascular function.

18 Jun 2013

Study shows brain abnormalities in MTBI patients closely resemble Alzheimer's dementia

The distribution of white matter brain abnormalities in some patients after mild traumatic brain injury (MTBI) closely resembles that found in early Alzheimer's dementia, according to a new study published online in the journal Radiology.

18 Jun 2013

Combination of obesity and low testosterone increases risk of diabetes and brain damage

Low testosterone worsens the harmful effects of obesity in the nervous system, a new study in mice finds. The results will be presented Monday at The Endocrine Society's 95th Annual Meeting in San Francisco.

18 Jun 2013

MGH researchers discover CNVs in members of 10 families with early-onset Alzheimer's

Although a family history of Alzheimer's disease is a primary risk factor for the devastating neurological disorder, mutations in only three genes - the amyloid precursor protein and presenilins 1 and 2 - have been established as causative for inherited, early-onset Alzheimer's, accounting for about half of such cases.

18 Jun 2013

Transition, Lilly amend agreement to address future development of TT-401

Transition Therapeutics Inc. announced that Eli Lilly and Company has exercised its option to assume all development and commercialization rights to type 2 diabetes drug candidate TT-401.

17 Jun 2013

HandsFree system helps analyze next generation sequencing data

In the early 1990s, an international effort was launched by the U.S. Department of Energy and the National Institutes of Health to sequence the human genome. The project took 13 years, involved many scientists in several countries, and cost $2.7 billion (in FY 1991) dollars.

15 Jun 2013

Gulf War illness may have two distinct forms, study says

Researchers at Georgetown University Medical Center say their new work suggests that Gulf War illness may have two distinct forms depending on which brain regions have atrophied. Their study of Gulf War veterans, published online today in PLOS ONE, may help explain why clinicians have consistently encountered veterans with different symptoms and complaints.

15 Jun 2013

Acrolein offers potential tool to reduce symptoms of spinal cord injuries and multiple sclerosis

A medical test previously developed to measure a toxin found in tobacco smokers has been adapted to measure the same toxin in people suffering from spinal cord injuries and multiple sclerosis, offering a potential tool to reduce symptoms.

14 Jun 2013

TAU researcher develops peptide to protect and restore microtubule function

A structure called "the microtubule network" is a crucial part of our nervous system. It acts as a transportation system within nerve cells, carrying essential proteins and enabling cell-to-cell communications. But in neurodegenerative diseases like Alzheimer's, ALS, and Parkinson's, this network breaks down, hindering motor abilities and cognitive function.

14 Jun 2013

Researchers at Albert Einstein College of Medicine convene one-day conference on Jewish genetics

Today, researchers at Albert Einstein College of Medicine of Yeshiva University convened a one-day conference on Jewish genetics designed to encourage collaboration and advance the field of research.

14 Jun 2013

Scientists measure major difference between brains of patients with Alzheimer's disease and healthy family members

Scientists at Washington University School of Medicine in St. Louis have measured a significant and potentially pivotal difference between the brains of patients with an inherited form of Alzheimer's disease and healthy family members who do not carry a mutation for the disease.

13 Jun 2013

Research reveals that men who experience RLS may have higher risk of dying earlier

Men who experience restless legs syndrome may have a higher risk of dying earlier, according to research that appears in the June 12, 2013, online issue of Neurology, the medical journal of the American Academy of Neurology.

13 Jun 2013

Common medications reduce brain plaques in mice

Multiple drug classes commonly prescribed for common medical conditions are capable of influencing the onset and progression of Alzheimer's disease, according to researchers at The Mount Sinai Medical Center. The findings are published online in the journal PLoS One.

13 Jun 2013

3D motion-tracked PET imaging uses MR micro-coils to reduce movement-related imaging artifacts

One of the biggest hurdles of hybrid positron emission tomography and magnetic resonance imaging is the prevalence of motion artifacts-blurring and ghostly visual anomalies caused by patient motion on the table during imaging.

13 Jun 2013

Hypometabolism in brain regions of cognitively normal patients associated with Alzheimer's disease

Alzheimer's disease has been linked in many studies to amyloid plaque buildup in the brain, but new research is finding a common thread between amyloid burden and lower energy levels, or metabolism, of neurons in certain areas of the brain associated with Alzheimer's disease-even for people with no sign of cognitive decline.

12 Jun 2013

Ireland's first functional brain mapping facility to be set up at University of Ulster's Magee campus

The first functional brain mapping facility on the island of Ireland is to be established at the University of Ulster's Magee campus.

12 Jun 2013

Viewpoints: Medicaid expansion 'makes sense'; Budget cuts hurt Alzheimer's research; Lack of transparency in generic Rx prices

The numbers in the Rand study ... should not be a surprise to people who have been paying attention. Numerous studies now, including in Missouri, have pointed to the simple reality of the policy implications of the ACA to argue for Medicaid expansion.

12 Jun 2013

Alzheimer's Disease News and Research

Further Reading

OHSU analysis finds previous studies have overstated effectiveness of bone growth product used in spinal surgeries

NIH awards $12.7M to research groups to explore new treatments for patients in eight disease areas

Lipidation states in certain proteins in the brain differ depending on genotype, cognitive diseases

Blocking B1R receptor activity in brains of Alzheimer's mice recovers memory and cerebrovascular function

Study shows brain abnormalities in MTBI patients closely resemble Alzheimer's dementia

Combination of obesity and low testosterone increases risk of diabetes and brain damage

MGH researchers discover CNVs in members of 10 families with early-onset Alzheimer's

Transition, Lilly amend agreement to address future development of TT-401

HandsFree system helps analyze next generation sequencing data

Gulf War illness may have two distinct forms, study says

Acrolein offers potential tool to reduce symptoms of spinal cord injuries and multiple sclerosis

TAU researcher develops peptide to protect and restore microtubule function

Researchers at Albert Einstein College of Medicine convene one-day conference on Jewish genetics

Scientists measure major difference between brains of patients with Alzheimer's disease and healthy family members

Research reveals that men who experience RLS may have higher risk of dying earlier

Common medications reduce brain plaques in mice

3D motion-tracked PET imaging uses MR micro-coils to reduce movement-related imaging artifacts

Hypometabolism in brain regions of cognitively normal patients associated with Alzheimer's disease

Ireland's first functional brain mapping facility to be set up at University of Ulster's Magee campus

Viewpoints: Medicaid expansion 'makes sense'; Budget cuts hurt Alzheimer's research; Lack of transparency in generic Rx prices

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer

Latest News