Antigen News and Research

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Cellular immunotherapy offers hope for solid tumors

Early findings from a small clinical trial provide evidence that a new cellular immunotherapy approach may be effective in treating metastatic solid tumors. In the trial, researchers from the National Institutes of Health (NIH) genetically engineered normal white blood cells, known as lymphocytes, from each patient to produce receptors that recognize and attack their specific cancer cells.

12 Jul 2024

Novel Co-STAR cells show promise in targeting and eradicating cancer

Using genetic engineering techniques, investigators at the Johns Hopkins Kimmel Cancer Center and its Ludwig Center, the Lustgarten Laboratory and Bloomberg~Kimmel Institute for Cancer Immunotherapy have designed a novel type of cell to recognize and fight cancer.

11 Jul 2024

Researchers identify two risk factors that indicate higher risk of aggressive prostate cancer

A recent European Urology Oncology study assessed the mortality risks, based on the Gleason score and clinical parameters, in patients with prostate cancer.

11 Jul 2024

Researchers identify shared molecular mechanism in cancer and pregnancy that suppresses immune system

Researchers elucidated the shared immune tolerance mechanisms in cancer and pregnancy, focusing on the role of an immune checkpoint protein as an onco-fetal immune tolerance checkpoint.

11 Jul 2024

Click-like chemistry enables rapid development of LNPs for enhanced mRNA delivery

Imagine a scenario where a skilled hacker must upload critical software to update a central server and thwart a potentially lethal virus from wreaking havoc across a vast computer network.

10 Jul 2024

Transforming growth factor beta inhibition boosts NK cell therapy against hepatocellular carcinoma

Researchers at University of California San Diego have found that the most common form of liver cancer - one with a high mortality rate - can be better targeted and treated using an innovative new stem cell-derived therapy, according to a recently published study in Cell Stem Cell.

9 Jul 2024

Innovative study on gut bacteria and T cells wins NOSTER & Science Microbiome Prize

In the gut, dozens of strains of bacteria exert different effects on the immune system that in turn impact our health – fending off pathogens, helping digest food and maybe even influencing behavior. But pinpointing which bacteria exert which effects has been challenging.

4 Jul 2024

PVP-037: A novel imidazopyrimidine adjuvant enhancing vaccine immune responses

Many vaccines are only partially effective, have waning efficacy, or do not work well in the very young or the very old.

3 Jul 2024

New hope for solid tumors with enhanced CAR-T cells

A promising therapy that treats blood cancers by harnessing the power of the immune system to target and destroy cancer cells could now treat solid tumors more efficiently. Thanks to a recent study published in Molecular Therapy – Methods & Clinical Development from Dan Cappabianca and Krishanu Saha at the Wisconsin Institute for Discovery, Chimeric Antigen Receptor (CAR) T-cell therapy can be improved by altering the conditions the T cells are grown in. And it was all discovered by chance.

3 Jul 2024

Innovative HIV vaccine approaches yield potential for broad protection against viral strains

A major challenge in developing a vaccine for HIV is that the virus mutates fast - very fast. Although a person initially becomes infected with one or a few HIV strains, the virus replicates and mutates quickly, resulting in a "swarm" of viral strains existing in a single body.

2 Jul 2024

Advancements in immunotherapy for hepatocellular carcinoma offer hope to patients

Hepatocellular carcinoma (HCC) is a primary liver cancer predominantly arising from chronic liver diseases such as hepatitis B and C infections, alcohol abuse, and metabolic disorders.

2 Jul 2024

Bird flu virus detected in Alaskan polar bear

Researchers reported a natural infection of a highly pathogenic avian influenza A(H5N1) virus in a free-ranging juvenile polar bear in Alaska, highlighting the importance of wildlife health surveillance in detecting emerging pathogens.

2 Jul 2024

Study alerts transwomen to interpret standard prostate cancer screening guidelines with caution

UCSF-led study alerts transwomen and physicians to interpret standard screening guidelines with caution.

28 Jun 2024

Hesse's LOEWE program supports cutting-edge CAR-T cell therapy research

LOEWE, the federal state of Hesse's research promotion program for the development of scientific and economic excellence, is providing €4.8 million in funding for a new research network spearheaded by Goethe University.

28 Jun 2024

Rice and MD Anderson collaborative harnesses engineering expertise for cancer solutions

Led by Rice's Gang Bao and MD Anderson's Dr. Jeffrey Molldrem, the initiative aims to foster collaboration between the two institutions on fundamental and translational cancer research, to develop new technologies for cancer detection and therapy and to secure external funding in support of further research and training.

27 Jun 2024

Current screening guidelines could miss prostate cancer in transgender women receiving estrogen

Transgender women are still at risk for prostate cancer. A new study led by Cedars-Sinai Cancer investigators, published in the peer-reviewed Journal of the American Medical Association, concludes that current screening guidelines could miss early-stage prostate cancer in transgender women on hormone therapy.

26 Jun 2024

Antigen News and Research

Cellular immunotherapy offers hope for solid tumors

Novel Co-STAR cells show promise in targeting and eradicating cancer

Researchers identify two risk factors that indicate higher risk of aggressive prostate cancer

Researchers identify shared molecular mechanism in cancer and pregnancy that suppresses immune system

Click-like chemistry enables rapid development of LNPs for enhanced mRNA delivery

Transforming growth factor beta inhibition boosts NK cell therapy against hepatocellular carcinoma

Innovative study on gut bacteria and T cells wins NOSTER & Science Microbiome Prize

PVP-037: A novel imidazopyrimidine adjuvant enhancing vaccine immune responses

New hope for solid tumors with enhanced CAR-T cells

Innovative HIV vaccine approaches yield potential for broad protection against viral strains

Advancements in immunotherapy for hepatocellular carcinoma offer hope to patients

Bird flu virus detected in Alaskan polar bear

Study alerts transwomen to interpret standard prostate cancer screening guidelines with caution

Hesse's LOEWE program supports cutting-edge CAR-T cell therapy research

Rice and MD Anderson collaborative harnesses engineering expertise for cancer solutions

Current screening guidelines could miss prostate cancer in transgender women receiving estrogen

Designing hybrid antibodies with enhanced mobility and signaling capacity

Study reveals cannabis and tobacco users face higher COVID-19 hospitalization and adverse outcomes

Study reveals early immune responses to SARS-CoV-2, offering insights for future COVID-19 treatments

New study reveals the therapeutic potential of ZED1227 in celiac disease

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Latest eBooks

Editorial Focus eBook - Spatial and single-cell omics (1st edition)

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics