Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

Early-life smoke exposure produces long-lasting sleep alterations in adult mice

Researchers of the University of Bologna carried out a study on murine models (mice) demonstrating that pre-natal exposure to nicotine and its by-products produces long-term effects on sleep and stress-response in some areas of the brain.

24 Jan 2022

Researchers discover mechanism behind SARS-CoV-2 entry into the brain

In a new study, researchers conducted an analysis of databases that have information on the transcriptomic and proteomic expression of ACE2, TMPRSS2, NRP1, and furin in several human brain areas.

24 Jan 2022

Even mild SARS-CoV-2 respiratory-only infection can cause long-term neurologic damage

A new bioRxiv* preprint study led by Michelle Monje of Stanford University in California finds that a mild COVID-19 infection can produce long-term neurological damage. Persistent cognitive complications are one of many symptoms of long COVID, and the latest results suggest the severity of COVID-19 induced brain fog is similar to cancer’s “chemobrain.”

16 Jan 2022

New neural circuits regulating spatial learning, memory in the brain's hippocampal formation discovered

A research team led by University of California, Irvine has discovered new neural circuits that regulate spatial learning and memory in the brain's hippocampal formation.

10 Jan 2022

Poor cognition may be part of normality in older age, research says

At the first sign of cognitive trouble, people often worry Alzheimer's disease is forthcoming. But poor cognition can be part of the spectrum of normality in older age, according to new research published in JNeurosci.

10 Jan 2022

Physical activity may help boost synaptic functioning in older adults

When elderly people stay active, their brains have more of a class of proteins that enhances the connections between neurons to maintain healthy cognition, a UC San Francisco study has found.

7 Jan 2022

New study links anxiety and PTSD to increased myelin in brain's gray matter

A recent study links anxiety behavior in rats, as well as post traumatic stress disorder (PTSD) in military veterans, to increased myelin - a substance that expedites communication between neurons - in areas of the brain associated with emotions and memory.

6 Jan 2022

A closer look at the relationship between COVID-19 and Alzheimer’s disease

Researchers discuss the findings of previous studies on the role of SARS-CoV-2 infection in the progression of Alzheimer's Disease.

4 Jan 2022

Combination of rifampicin and resveratrol helps stop dementia, finds study

Dementia is thought to occur when proteins called amyloid-β, tau, and α-synuclein accumulate in the brain and form oligomers. A research group from the Department of Translational Neuroscience, Osaka City University Graduate School of Medicine, had previously shown in a study using mice that the antibiotic rifampicin removes oligomers from the brain and improves cognitive function.

29 Dec 2021

Star-shaped cells in the brain regulate cognitive flexibility

As we live in a dynamically changing environment, it is important for our brain to not only learn new things but also to modify existing memories.

21 Dec 2021

Deletion of autism-linked gene diminishes myelin in mice

Myelin, a sheath of insulation around nerves that enables electrical impulses to efficiently travel through the central nervous system, is diminished in mice that have a gene deletion associated with autism spectrum disorder, new research finds.

21 Dec 2021

Novel imaging method used to map glycosylation patterns linked with Alzheimer’s disease

Using new methodology, University of Kentucky researchers have mapped the variations in sugar chains attached to brain proteins from deceased healthy individuals or individuals with Alzheimer's disease.

15 Dec 2021

Exercise 'sweet spot' reverses cognitive decline in aging mice

University of Queensland researchers have discovered an exercise 'sweet spot' that reverses the cognitive decline in aging mice, paving the way for human studies.

13 Dec 2021

Nasal infection drives lethal lung injury due to SARS-CoV-2 in mice

A new study demonstrates lethal infection of the olfactory epithelium in a mouse model that could help understand the mechanisms of COVID-19.

12 Dec 2021

Researchers discover clearest evidence to date of how memories form

In a discovery that could one day benefit people suffering from traumatic brain injury, Alzheimer's disease, and schizophrenia, UT Southwestern researchers have identified the characteristics of more than 100 memory-sensitive neurons that play a central role in how memories are recalled in the brain.

6 Dec 2021

MRI uncovers significant changes in the brain structure of fetuses exposed to alcohol

In the first MRI-based study to investigate pre-natal alcohol exposure, researchers found significant changes in the brain structure of fetuses exposed to alcohol compared to healthy controls. Results of the study are being presented today at the annual meeting of the Radiological Society of North America (RSNA).

1 Dec 2021