Nucleotide News and Research

RSS

SARS-CoV-2 evolutionary trends provide insights into its adaptive process to human hosts

The loss of genome heterogeneity in CoVs leads to high viral fitness variants that adapt to the human host.

31 May 2022

First-of-its-kind platform generates antitumor immunity and improves responses to checkpoint inhibitors

Researchers at The University of Texas MD Anderson Cancer Center have developed an ultrasound-guided cancer immunotherapy platform that generates systemic antitumor immunity and improves the therapeutic efficacy of immune checkpoint blockade.

30 May 2022

Penn biologists show evidence of a two-sided genomic arms race involving repetitive DNA

Biological arms races are commonplace in nature. Cheetahs, for example, have evolved a sleek body form that lends itself to rapid running, enabling them to feast upon similarly speedy gazelles, the fastest of which may evade predation.

27 May 2022

Nanotechnology enhanced DNA-chip for SARS-CoV-2 detection with variant differentiation

Researchers differentiated between SARS-CoV-2 variants using nanotechnology.

26 May 2022

Study explores the substrate selectivity of the SARS-CoV-2 replicase

Researchers explored factors affecting substrate selection by the SARS-CoV-2 replicase.

24 May 2022

Study sheds light on the molecular biology behind genetic epilepsy

Sometimes, even the alteration of a single nucleotide in a gene can cause serious disease. In a young boy with epilepsy, this kind of mutation has not just affected the functioning of the protein in question – it could also curb the functioning of several closely related proteins.

23 May 2022

Study demonstrates that ATV006 is orally bioavailable and has potent efficacy against SARS-CoV-2

A new study has revealed that ATV006, which is a 5′-hydroxyl-isobutyryl prodrug, possesses extraordinary oral pharmaco-kinetic (PK) profiles in rats and cynomolgus monkeys and exhibited significant antiviral activity against ancestral SARS-COV-2 strain as well as VOCs.

20 May 2022

Exploring cross-neutralizing anti-SARS-CoV-2 antibody responses among the general population

Researchers performed a molecular analysis of cross-reactive antibodies targeted against the receptor-binding domain of SARS-CoV-2 strains among the general population.

20 May 2022

Outlier detection of SARS-CoV-2 sequences

In a new study, researchers predicted SARS-CoV-2 nucleotide sequences using outlier detection.

19 May 2022

Genetics and environmental factors contribute to how socioeconomic status shapes the brain architecture

Your education, your job, your income, the neighborhood you live in: Together these factors are considered to represent socioeconomic status (SES) and contribute to a variety of health and social outcomes, from physical and mental health to educational achievement and cognitive capacities.

18 May 2022

Case report: human breast milk from vaccinated woman clears persistent SARS-CoV-2 infection

A new study published in the journal Viruses aimed to report the effects of plasma infusion and then breastmilk ingestion as a therapy for persistent SARS-CoV-2 infection in a patient with a common variable immunodeficiency (CVID) phenotype.

18 May 2022

Tabula sapiens, most comprehensive human cell atlas

In a recent study published in the journal Science, researchers created an atlas termed the Tabula sapiens for over 400 distinct cell types of humans. Several aspects of human physiology were revealed by the atlas, such as how different types of cells splice genes differently.

16 May 2022

Characterizing SARS-CoV-2 non-structural protein 15 endoribonuclease variants

In a recent study posted to the bioRxiv* pre-print server, researchers characterized the mutations in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) non-structural protein 15 (Nsp-15).

16 May 2022

CDC study reveals hybrid SARS-CoV-2 spike from Delta/Omicron recombination event

The US Centers for Disease Control and Prevention (CDC) has conducted national-level genomic surveillance to identify and characterize delta-omicron recombinant genomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A total of nine genomes with a hybrid delta-omicron spike protein have been identified.

14 May 2022

Direct infection and replication of influenza virus in cardiomyocytes is a primary determinant of cardiac pathology associated with severe influenza

Researchers generated a recombinant influenza virus expressing micro ribonucleic acid (miRNAs) expressed in cardiomyocytes to infect mice, which served as a model to study the etiology of influenza-associated cardiac pathology.

13 May 2022

Nucleotide News and Research

SARS-CoV-2 evolutionary trends provide insights into its adaptive process to human hosts

First-of-its-kind platform generates antitumor immunity and improves responses to checkpoint inhibitors

Penn biologists show evidence of a two-sided genomic arms race involving repetitive DNA

Nanotechnology enhanced DNA-chip for SARS-CoV-2 detection with variant differentiation

Study explores the substrate selectivity of the SARS-CoV-2 replicase

Study sheds light on the molecular biology behind genetic epilepsy

Study demonstrates that ATV006 is orally bioavailable and has potent efficacy against SARS-CoV-2

Exploring cross-neutralizing anti-SARS-CoV-2 antibody responses among the general population

Outlier detection of SARS-CoV-2 sequences

Genetics and environmental factors contribute to how socioeconomic status shapes the brain architecture

Case report: human breast milk from vaccinated woman clears persistent SARS-CoV-2 infection

Tabula sapiens, most comprehensive human cell atlas

Characterizing SARS-CoV-2 non-structural protein 15 endoribonuclease variants

CDC study reveals hybrid SARS-CoV-2 spike from Delta/Omicron recombination event

Direct infection and replication of influenza virus in cardiomyocytes is a primary determinant of cardiac pathology associated with severe influenza

Worldwide study of diverse populations sheds new light on how genes contribute to type 2 diabetes

Research describes how DNA damage can affect neural health and function

Researchers find gene that shapes mutation rate in mice

Deep learning reveals genetic determinants of COVID-19-associated mortality

Scientists explore immunopathology of COVID-19

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer

Latest News