Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Cancer cells hide inside bone marrow fibroblasts to resist treatment

In a recently published study, researchers at Fox Chase Cancer Center revealed for the first time that cancer cells can evade anti-cancer drugs by entering and surviving within bone marrow fibroblasts, a phenomenon they describe as "cell-in-cell."

12 Aug 2025

RSNA AI Challenge models show excellent performance for detecting breast cancers on mammograms

Algorithms submitted for an AI Challenge hosted by the Radiological Society of North America (RSNA) have shown excellent performance for detecting breast cancers on mammography images, increasing screening sensitivity while maintaining low recall rates, according to a study published today in Radiology, the premier journal of the RSNA.

12 Aug 2025

Women with Down syndrome show more advanced Alzheimer's signs at diagnosis

According to research by the University of California, Irvine, women with Down syndrome have more advanced signs of Alzheimer's disease than men do at the average age of diagnosis, which is the same for both sexes.

12 Aug 2025

Special von Economo neurons may hold key to super-sharp memory in 80+ superagers

Researchers at Northwestern University’s SuperAging Program reveal how some people over 80 retain memory performance like those decades younger, linking it to unique brain structures, reduced pathology, and lower inflammation. Their 25-year study highlights genetic, cellular, and social traits that may protect cognitive function.

10 Aug 2025

Lithium deficiency emerges as a hidden driver of Alzheimer’s

What is the earliest spark that ignites the memory-robbing march of Alzheimer’s disease? Why do some people with Alzheimer’s-like changes in the brain never go on to develop dementia? These questions have bedeviled neuroscientists for decades.

8 Aug 2025

Alzheimer’s research reaches a critical tipping point

One-third of people older than 85 in the United States are estimated to live with Alzheimer's disease today, according to the National Institute on Aging.

8 Aug 2025

Scientists link brain lithium loss to early Alzheimer’s changes

Researchers have discovered that naturally occurring lithium in the brain is depleted early in Alzheimer’s disease, especially in the prefrontal cortex, and that restoring physiological levels with lithium orotate in mice can prevent brain damage and memory loss. The findings suggest lithium deficiency may be a modifiable risk factor for Alzheimer’s.

7 Aug 2025

Cedars-Sinai study finds new way to combat Alzheimer’s in preclinical models

In a preclinical study, Cedars-Sinai investigators found that boosting angiotensin converting enzyme (ACE) in key immune cells called microglia in the brain helped protect the brains of specially bred laboratory mice against Alzheimer's disease.

6 Aug 2025

Targeted microglia replacement shows promise against fatal neurodegenerative conditions

Tay-Sachs and Sandhoff diseases, genetic disorders affecting the brain, have no effective treatment and are typically fatal within the first years of life.

6 Aug 2025

New tool offers a more precise way to assess stroke risk in people with atrial fibrillation

Researchers at the University of Vermont have developed a more precise way to assess stroke risk in people with atrial fibrillation (A-Fib), a condition that affects 10.5 million Americans and is a leading cause of stroke.

6 Aug 2025

Lipid droplet protein perilipin 2 linked to poor prognosis in lung cancer

New research has revealed that perilipin 2 protein modulates aggressive cancer progression in advanced lung adenocarcinoma, the most common type of lung cancer, by regulating lipid droplet accumulation, which plays an important role in lipid metabolism by making cancer cells store more fat, acting as a fuel source.

5 Aug 2025

New research unveils vast influence of B vitamins on health and disease

Eight essential nutrients make up the suite of B vitamins also known as the B complex. Researchers from Tufts University and elsewhere have revealed that these B vitamins influence a vast spectrum of human health and disease, including cognitive function, cardiovascular health, gastric bypass recovery, neural tube defects, and even cancer.

4 Aug 2025

New research highlights exercise's broad impact in Parkinson's disease

It was the early 2000s when researchers first showed that exercise can help relieve the tremors that are common with Parkinson's Disease.

4 Aug 2025

Immune molecule found to play a key role in regulating inflammation in rheumatoid arthritis

Researchers at Kyoto University have discovered that an immune molecule found only in primates, called IGFL2, plays a key role in regulating inflammation in rheumatoid arthritis (RA).

1 Aug 2025

New insights reveal how Candida albicans settle and persist in the gut

About 80% of people have the fungus Candida albicans in their gut. Although most of the time it persists unnoticed for years causing no health problems, C. albicans can turn into a dangerous microbe that causes serious diseases in many organs, including the urinary tract, lungs and brain.

30 Jul 2025

Antiviral treatment shows no benefit for early Alzheimer’s patients

The idea that herpes infections trigger or contribute to Alzheimer's disease has been gaining favor among some scientists, raising hope that herpes treatments could slow progression of Alzheimer's symptoms among patients.

30 Jul 2025

AI algorithm identifies one-third of missed breast cancers in DBT screenings

An AI algorithm for breast cancer screening has potential to enhance the performance of digital breast tomosynthesis (DBT), reducing interval cancers by up to one-third, according to a study published today in Radiology, a journal of the Radiological Society of North America.

29 Jul 2025