Inflammation News and Research

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Dual-receptors help widespread dissemination of SARS-CoV-2

Researchers demonstrate the role of integrins in the establishment of the SARS-CoV-2 infection.

9 Jan 2022

Researchers investigate SARS-CoV-2 specific inflammatory response

New research can confirm that while some of the response from monocytes to SARS-CoV-2 is generic to virus infection, most of it SARS-CoV-2 specific, especially proinflammatory responses.

7 Jan 2022

Multisystem inflammatory syndrome in children rare after COVID-19 vaccination in adolescents

The current study was based on merged results using the CDD’s surveillance database coupled with the Vaccine Adverse Event Reporting System (VAERS), along with reports from health departments or physicians to the CDC.

7 Jan 2022

Association of obstructive sleep apnea with hospitalization due to COVID-19

Researchers report that OSA is an independent risk factor for severe COVID-19.

7 Jan 2022

SARS-CoV-2 Omicron less pathogenic in hamsters

A new research paper posted as a preprint to the bioRxiv* server attempts to throw some light on this question by studying viral pathogenicity in golden hamsters, a valuable model for severe COVID-19 due to the development of reproducible weight loss and pneumonia after infection with the virus.

6 Jan 2022

New approach with mRNA preparation reprograms T cells to attack heart fibroblasts

An experimental immunotherapy can temporarily reprogram patients' immune cells to attack a specific target via only a single injection of messenger RNA (mRNA), similar to the mRNA-based COVID-19 vaccines, according to a new study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

6 Jan 2022

Switching to smokeless tobacco associated with lower cardiovascular disease risk in smokers

Regular smokers are at heightened risk of developing cardiovascular disease, but crushing the butts in favor of a "smokeless" alternative like chewing tobacco, snuff or tobacco lozenges may go a long way toward bringing the danger down to a more normal level, a new UCLA-led study shows.

6 Jan 2022

Melatonin found to inhibit SARS-CoV-2 entry into mice brains

New research recently unveiled the utility of melatonin and melatonin-derived medicines in reducing brain entry of severe acute respiratory syndrome coronavirus 2 and subsequently preventing long-term neurological consequences of coronavirus disease 2019.

6 Jan 2022

SARS-CoV-2 appears to persist in organs throughout the body for months

The coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), leads to asymptomatic or mild symptoms in most cases. However, in a significant minority, it causes moderate or severe disease, with lung damage and sometimes multi-organ dysfunction, the origin of which is currently a matter of intense debate.

6 Jan 2022

LIVE-AIR trial demonstrates efficacy of Lenzilumab for treatment of COVID patients with decreased oxygen saturation

The LIVE-AIR phase 3 clinical trial is associated with early treatment of hyperinflammatory response with the humanized monoclonal antibody lenzilumab in COVID-19 patients with decreased oxygen saturation. The study results are posted to the medRxiv* preprint server.

6 Jan 2022

Study estimates the burden of pediatric asthma cases caused by traffic- related air pollution

Nearly 2 million new cases of pediatric asthma every year may be caused by a traffic-related air pollutant, a problem particularly important in big cities around the world, according to a new study published today.

5 Jan 2022

Change in glutathione reductase lowers inflammation in present-day humans

Very few proteins in the body have a change that makes them unique compared to the corresponding proteins in Neanderthals and apes.

5 Jan 2022

Scientists unravel how LPS prevents or promotes development of allergic disease

Immunologists have long been baffled by LPS, the bacterial lipopolysaccharide that helps form the cell walls of Gram-negative bacteria.

5 Jan 2022

First-responder cells launching the repair after heart attack promote inflammation overdrive

First-responder cells launching the repair after a heart attack are so frantic about fixing the damage that they promote more inflammation than necessary, new research in mice suggests.

5 Jan 2022

Study uncovers a harmful neutrophil behavior linked to cardiovascular disease

Scientists led by Dr. Andrés Hidalgo at the Centro Nacional de Investigadores Cardiovasculares have discovered that circulating neutrophils - a type of immune cell - acquire different behavior patterns during inflammatory processes.

5 Jan 2022

Drugs that block mineralocorticoid receptor may help protect bone cells during aging

Drugs we take like prednisone can weaken our bones and so can aging, and scientists working to prevent both have some of the first evidence that the best target may not be the logical one.

5 Jan 2022

Novel insight into the immune characteristics of bats

Many studies have indicated that bats are significant reservoirs of innumerable viruses, such as influenza, coronaviruses, and rabies. These studies have also reported that bats predominantly remain asymptomatic or develop mild diseases during viral infections caused by henipaviruses, Ebola virus, coronaviruses, etc.

4 Jan 2022

Inflammation News and Research

Dual-receptors help widespread dissemination of SARS-CoV-2

Researchers investigate SARS-CoV-2 specific inflammatory response

Multisystem inflammatory syndrome in children rare after COVID-19 vaccination in adolescents

Association of obstructive sleep apnea with hospitalization due to COVID-19

SARS-CoV-2 Omicron less pathogenic in hamsters

New approach with mRNA preparation reprograms T cells to attack heart fibroblasts

Switching to smokeless tobacco associated with lower cardiovascular disease risk in smokers

Melatonin found to inhibit SARS-CoV-2 entry into mice brains

SARS-CoV-2 appears to persist in organs throughout the body for months

LIVE-AIR trial demonstrates efficacy of Lenzilumab for treatment of COVID patients with decreased oxygen saturation

Study estimates the burden of pediatric asthma cases caused by traffic- related air pollution

Change in glutathione reductase lowers inflammation in present-day humans

Scientists unravel how LPS prevents or promotes development of allergic disease

First-responder cells launching the repair after heart attack promote inflammation overdrive

Study uncovers a harmful neutrophil behavior linked to cardiovascular disease

Drugs that block mineralocorticoid receptor may help protect bone cells during aging

Novel insight into the immune characteristics of bats

Scientists find that having one kind of autoimmune disease can lead to another

Both symptomatic and asymptomatic COVID-19 associated with increased risk of cardiovascular events

A closer look at the relationship between COVID-19 and Alzheimer’s disease

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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