Efficacy News and Research

RSS

A systematic review of in vitro studies evaluating the efficacy of mouth rinses on SARS-CoV-2

A new study aims to evaluate the current body of published in vitro research related to the efficacy of mouthwashes in preventing SARS-CoV-2 transmission.

20 Aug 2021

A combination of oral bacteria and intranasal vaccine provide protection from influenza A virus and COVID-19

A new study published in the journal mBio focuses on the role of nasal bacteria in eliciting virus-specific adaptive immunity.

20 Aug 2021

Systematic review: Efficacy and renal tolerability of ultrafiltration in acute decompensated heart failure

In a new publication from Cardiovascular Innovations and Applications, Yajie Liu and Xin Yuan from the Second Affiliated Hospital of Chongqing Medical University, Chongqing, China consider the efficacy and renal tolerability of ultrafiltration in acute decompensated heart failure.

20 Aug 2021

Expert review on the achievements and shortcomings of EU's COVID-19 response

A new study in Frontiers in Public Health presents a review of expert opinions on the achievements and shortcomings of the European Union's (EU) COVID-19 response. The aim: to draw lessons for future pandemics.

20 Aug 2021

MHRA approves first monoclonal antibody treatment for COVID-19 in the UK

Following on from a thorough review of the evidence carried out by the MHRA, and recommendation by the Commission on Human Medicines (CHM), the government's independent expert scientific advisory body, the MHRA has approved Ronapreve as the first monoclonal antibody combination product indicated for use in the prevention and treatment of acute COVID-19 infection for the UK.

20 Aug 2021

3D-printed tumors potentially next step in personalized medicine

Scientists at Tel Aviv University have successfully printed an entire active and viable brain tumor using a three-dimensional or 3D printer for the first time.

20 Aug 2021

SARS-CoV-2 mutations alter dynamics of neutralizing antibodies

A new study describes how monoclonal antibodies raised against SARS-CoV-2 are affected by mutations in the antibody binding site.

20 Aug 2021

SARS-CoV-2 lambda variant escapes immune response via spike mutations

A new study explores the mechanism by which the SARS-CoV-2 lambda variant has acquired immune evasion capabilities above that of the wildtype.

20 Aug 2021

‘We sent a terrible message’: Scientists say Biden jumped the gun with vaccine booster plan

The Biden administration's plans to make covid-19 booster shots available next month has drawn a collective scream of protest from the scientific community.

20 Aug 2021

Low-cost point of emission air purifiers can reduce airborne transmission of pathogens, says study

In a study conducted at the Monash University, Australia, scientists have examined the efficacy of portable air purifiers combined with a hood in reducing virus aerosol transmission and protecting healthcare workers from workplace contamination. The study is currently available on the medRxiv* preprint server.

20 Aug 2021

Prior treatment may impact efficacy of ACT-TIL in patients with metastatic melanoma

Patients with metastatic melanoma that had relapsed on anti-PD-1 therapies or BRAF/MEK inhibitors did not respond as well to an investigational therapy that involves the adoptive cell transfer of tumor-infiltrating lymphocytes (ACT-TIL) as patients naïve to these treatments.

19 Aug 2021

Cognitive rehabilitation found to be effective in treating multiple sclerosis-related cognitive dysfunction

In a review of recent literature, a team of researchers from Kessler Foundation conclude that cognitive rehabilitation programs are efficacious in treating multiple sclerosis-related cognitive dysfunction, and urge clinicians to consider this low-cost, low-risk, yet effective treatment approach for their patients.

19 Aug 2021

Hidradenitis suppurativa: Discontinuation of adalimumab prior to surgery is not necessary

Hidradenitis suppurativa (Syn. Acneinversa) is one of the most troublesome and complicated skin diseases. The anti-inflammatory drug adalimumab can improve symptoms; however, patients also often have to undergo surgery.

19 Aug 2021

Vaccines remain the most effective way to protect against COVID-19 Delta variant, study says

Obtaining two vaccine doses remains the most effective way to ensure protection against the COVID-19 Delta variant of concern dominant in the UK today, according to a study from the University of Oxford.

19 Aug 2021

Existing drugs block or reduce SARS-CoV2 infection in cells

Since the beginning of the pandemic, researchers worldwide have been looking for ways to treat COVID-19. And while the COVID-19 vaccines represent the best measure to prevent the disease, therapies for those who do get infected remain in short supply.

19 Aug 2021

Durable highly protective T cell response to AAV-spike vaccine against COVID-19 pneumonia in mice

New research, available as a preprint on the bioRxiv* server, has focused on the role played by T cell immunity, particularly CD8+ cytotoxic T cells, on preventing lethal infection with SARS-CoV-2 in mice infused with peptide-loaded antigen-presenting dendritic cells (DCs).

19 Aug 2021

Early clinical trial data in for whole virus COVID-19 vaccine candidate

In a study uploaded to the preprint server medRxiv*, the efficacy of a whole virion Coronavirus vaccine was determined by giving the vaccine to healthy adult volunteers, which generated a robust immune response with evidence of T-cell activation.

19 Aug 2021

SARS-CoV-2 vaccine efficacy is strongly correlated with antibody neutralization levels

All COVID-19 vaccines appear less effective when faced with variants such as Delta, according to a new medRxiv* study. However, the researchers suggest that booster shots may help improve immunity and protect against symptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

18 Aug 2021

Vaccine nationalism may increase COVID-19 case numbers and the emergence of novel variants

The allocation of COVID-19 vaccine between countries has thus far tended toward vaccine nationalism, wherein countries stockpile vaccines to prioritize access for their citizenry over equitable vaccine sharing.

18 Aug 2021

Researchers create the first 3D-bioprinted model of active glioblastoma tumor

A scientific achievement for researchers at Tel Aviv University: printing an entire active and viable glioblastoma tumor using a 3D printer.

18 Aug 2021

Efficacy News and Research

A systematic review of in vitro studies evaluating the efficacy of mouth rinses on SARS-CoV-2

A combination of oral bacteria and intranasal vaccine provide protection from influenza A virus and COVID-19

Systematic review: Efficacy and renal tolerability of ultrafiltration in acute decompensated heart failure

Expert review on the achievements and shortcomings of EU's COVID-19 response

MHRA approves first monoclonal antibody treatment for COVID-19 in the UK

3D-printed tumors potentially next step in personalized medicine

SARS-CoV-2 mutations alter dynamics of neutralizing antibodies

SARS-CoV-2 lambda variant escapes immune response via spike mutations

‘We sent a terrible message’: Scientists say Biden jumped the gun with vaccine booster plan

Low-cost point of emission air purifiers can reduce airborne transmission of pathogens, says study

Prior treatment may impact efficacy of ACT-TIL in patients with metastatic melanoma

Cognitive rehabilitation found to be effective in treating multiple sclerosis-related cognitive dysfunction

Hidradenitis suppurativa: Discontinuation of adalimumab prior to surgery is not necessary

Vaccines remain the most effective way to protect against COVID-19 Delta variant, study says

Existing drugs block or reduce SARS-CoV2 infection in cells

Durable highly protective T cell response to AAV-spike vaccine against COVID-19 pneumonia in mice

Early clinical trial data in for whole virus COVID-19 vaccine candidate

SARS-CoV-2 vaccine efficacy is strongly correlated with antibody neutralization levels

Vaccine nationalism may increase COVID-19 case numbers and the emergence of novel variants

Researchers create the first 3D-bioprinted model of active glioblastoma tumor

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News