Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

New therapies for acute kidney injury show promise

Acute kidney injury (AKI) is a severe renal disorder affecting approximately 10%-15% of hospitalized patients and up to 50% in intensive care units (ICUs). Its pathogenesis involves complex inflammatory regulatory mechanisms. As core components of the cytokine network, interleukins (ILs) exert pleiotropic effects in AKI development, extensively participating in inflammation, fibrosis, tissue injury repair, and remote organ damage.

18 Aug 2025

AI voice test could help spot dangerous throat lesions before symptoms appear

Researchers at Oregon Health and Science University found that variability in the harmonic-to-noise ratio (HNR) of speech could help distinguish benign from malignant vocal fold lesions, offering a potential early detection biomarker. The exploratory study used AI to analyze acoustic features from the Bridge2AI-Voice dataset and found differences most pronounced in male participants.

14 Aug 2025

Reengineered enzyme enables precise detection of cell surface glycans

Sugars known as glycans form dense envelopes around cells. But they're often ignored in biological investigations because, unlike DNA, proteins and other cellular components, tools to study them are lacking.

14 Aug 2025

Genicular artery embolization relieves chronic knee pain caused by osteoarthritis

A procedure performed under mild sedation in less than two hours by an interventional radiologist relieves chronic knee pain caused by osteoarthritis, an NYU Langone Health study shows.

14 Aug 2025

Study investigates aging-related mechanisms in idiopathic pulmonary fibrosis using AI approaches

Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease characterized by the excessive accumulation of extracellular matrix components, leading to a gradual decline in lung function and, ultimately, respiratory failure.

13 Aug 2025

Women with Down syndrome show more advanced Alzheimer's signs at diagnosis

According to research by the University of California, Irvine, women with Down syndrome have more advanced signs of Alzheimer's disease than men do at the average age of diagnosis, which is the same for both sexes.

12 Aug 2025

Study identifies biomarkers that could help predict and manage chronic kidney disease

Biomarkers that could help predict and manage chronic kidney disease (CKD) have been identified in a new study led by the University of Surrey.

12 Aug 2025

AI detects early signs of laryngeal cancer from voice recordings

Cancer of the voice box or larynx is an important public health burden. In 2021, there were an estimated 1.1 million cases of laryngeal cancer worldwide, and approximately 100,000 people died from it. Risk factors include smoking, alcohol abuse, and infection with human papillomavirus.

12 Aug 2025

RSPO2 gene identified as key driver in metastatic prostate cancer

A new research paper was published in Volume 16 of Oncotarget on July 25, 2025, titled "Dissecting the functional differences and clinical features of R-spondin family members in metastatic prostate cancer."

11 Aug 2025

New biomarker may be the first specific and quantifiable indicator for confirming long COVID

Researchers from the Translational Genomics Research Institute (TGen), part of City of Hope, and the Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center have identified a potential biomarker for long COVID.

11 Aug 2025

Using machine learning framework to identify prognostic biomarkers in neuroblastoma

Neuroblastoma is the most common solid tumor in infants and accounts for nearly 15% of all pediatric cancer-related deaths.

11 Aug 2025

Epigenetic breakthrough: $200 blood test spots diabetes heart risk better than standard tools

Researchers have developed a blood-based DNA methylation risk score that predicts first macrovascular events in newly diagnosed type 2 diabetes patients more accurately than current cardiovascular risk tools. The score, when combined with clinical factors, could help target early prevention in high-risk individuals.

11 Aug 2025

Alzheimer’s research reaches a critical tipping point

One-third of people older than 85 in the United States are estimated to live with Alzheimer's disease today, according to the National Institute on Aging.

8 Aug 2025

AI-powered sweat sensor predicts anxiety before symptoms appear

Researchers have developed Stressomic, a wearable microfluidic biosensor that sequentially measures cortisol, epinephrine, and norepinephrine in sweat at six-minute intervals. The device distinguishes physical from psychological stress and predicts anxiety levels using machine learning.

7 Aug 2025

New microscope system reveals molecular activity deep in the brain tissue

Both for research and medical purposes, researchers have spent decades pushing the limits of microscopy to produce ever deeper and sharper images of brain activity, not only in the cortex but also in regions underneath such as the hippocampus.

7 Aug 2025

Smart wound patch detects healing progress and infection risk

RMIT's Bluetooth-enabled flexible sensor patch monitors wound healing, detecting biomarkers and vital signs without dressing removal for improved patient care.

6 Aug 2025

Magnesium deficiency drives higher mortality in hyperlipidemia

MgDS serves as a potential biomarker for mortality risk in hyperlipidemic adults, emphasizing the need for targeted approaches to manage cardiovascular health.

6 Aug 2025

Are all healthy diets equal or does food processing make a difference?

A randomized crossover trial in the UK found that both ultra-processed (UPF) and minimally processed food (MPF) diets, when aligned with national guidelines, led to weight loss in adults with overweight or obesity. However, the MPF diet produced significantly greater reductions in weight, fat mass, and food cravings, highlighting the added benefits of limiting food processing.

5 Aug 2025

New initiative expands screening for cardiovascular disease marker in community health centers

Elevated lipoprotein(a), also known as Lp(a), is an independent, inherited and causal risk factor for cardiovascular disease, the leading cause of death and disability worldwide.

5 Aug 2025

Spear Bio announces strategic partnership with Bio-Techne to accelerate the deployment of its next-generation immunoassay technology

Spear Bio, a biotechnology company pioneering homogeneous ultrasensitive immunoassay technology, is pleased to announce a strategic distribution partnership with Bio-Techne Corporation, a global leading provider of innovative reagents, instruments, and solutions for life-science research and clinical diagnostics.

From Spear Bio 5 Aug 2025