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Long-acting antiretroviral treatment may improve outcomes in underserved HIV patients

A long-acting antiretroviral treatment (LA-ART) given every four to eight weeks, and delivered with comprehensive support services, suppressed HIV in people who were previously not virologically suppressed.

21 Feb 2023

Researchers reveal the metabolic reactions upon activating Akt2 enzyme

Takeaki Ozawa and his team from the University of Tokyo reveal the metabolic reactions upon activating an enzyme called Akt2. In doing so, they reveal the inner workings of insulin-regulated metabolism.

21 Feb 2023

New approach to pain management can reduce opioid use after urethroplasty

For men undergoing surgery to repair scarring in the urethra (urethroplasty), a new approach to pain management can reduce the need for strong opioid drugs without compromising pain control, reports a study in Urology Practice, an Official Journal of the American Urological Association.

21 Feb 2023

Two new zebrafish models for studying the most common cause of Leigh syndrome developed

Researchers from Children's Hospital of Philadelphia (CHOP) developed two new zebrafish models for studying a specific genetic form of mitochondrial disease that represents the most common cause of Leigh syndrome.

21 Feb 2023

Life Sciences Innovator Category Winner 2023

Following a rigorous application process, we are proud to announce that Seda have been selected as the UK Life Sciences Innovator Winner 2023 in the Application, Product & Service Design Category.

From Seda Pharmaceutical Development Services 21 Feb 2023

Oxford-Harrington Rare Disease Centre hosts virtual event in honor of the upcoming Rare Disease Day

The Oxford-Harrington Rare Disease Centre, a partnership of the University of Oxford and Harrington Discovery Institute at University Hospitals, is hosting a virtual event on Monday, Feb. 27, 2023, in honor of the upcoming Rare Disease Day, which is celebrated across the globe on February 28 every year.

21 Feb 2023

Ethnic and regional minorities derive at least as much cardiovascular benefit from lipid-lowering therapies

Minority ethnicities and regions derive at least as much cardiovascular benefit from lipid-lowering therapies as majority groups despite being underrepresented in clinical trials, according to a study published today in the European Journal of Preventive Cardiology, a journal of the ESC.

21 Feb 2023

A law was meant to free sick or aging inmates. Instead, some are left to die in prison.

Jimmy Dee Stout was serving time on drug charges when he got grim news early last year.

21 Feb 2023

HKU research advances understanding of the fundamental biological processes of gene regulation

A research team from the University of Hong Kong led by Professor Xiang David Li from the Department of Chemistry in collaboration with Dr Yuanliang Zhai from the HKU School of Biological Sciences and Dr Jason Wing Hon Wong and Dr Xiucong Bao from the HKU School of Biomedical Sciences recently made a key breakthrough in understanding how genetic information encoded in our DNA is 'read' and why errors in 'reading' such information can often lead to developmental defects or cancers.

20 Feb 2023

Use of dapivirine vaginal ring during third trimester of pregnancy poses no safety concerns

A vaginal ring containing the antiretroviral drug dapivirine posed no safety concerns when used in the third trimester of pregnancy, according to results to date from the first study of the dapivirine ring during pregnancy and one of only a few studies of an HIV prevention product in pregnant cisgender women.

20 Feb 2023

Structure of DREADD designer receptor could pave the way for creating next generation tools

In order to more fully understand how diseases arise in the brain, scientists must unravel the intricate way neurons relay messages (either chemical or electrical) along a complex web of nerve cells.

20 Feb 2023

Ketamine appears to hold promise in treating cocaine-use disorders

As cocaine use continues to climb across the United States, scientists have struggled to develop an effective pharmacological approach to treat the devastating disorder.

20 Feb 2023

Study finds fiftyfold increase in U.S. methamphetamine mortality rate between 1999 and 2021

The U.S. methamphetamine mortality rate increased fiftyfold between 1999 and 2021, with most of the added deaths also involving heroin or fentanyl, researchers report in the American Journal of Public Health.

20 Feb 2023

Activating or deactivating drugs with the help of light

Scientists at the Paul Scherrer Institute PSI have used the Swiss X-ray free-electron laser SwissFEL and the Swiss Light Source SLS to make a film that could give a decisive boost to developing a new type of drug.

20 Feb 2023

Utilizing CRISPR to discover new therapy options for COPD

In this interview, we speak to Ceri Wiggins, a Director at AstraZeneca, about the many applications of CRISPR and its role in discovering new COPD therapies.

From Society for Laboratory Automation and Screening (SLAS) 20 Feb 2023

Are SGLT2 inhibitors the next blockbuster drug?

Recent clinical trials investigating the therapeutic potency of sodium-glucose cotransporter 2 inhibitors (SGLT2i) have highlighted that this drug is highly effective in treating patients with cardiovascular and renal diseases.

19 Feb 2023

New method to measure drugs and lipids in cells could lead to effective treatments for diseases

A new state-of-the-art method that measures the amounts of drugs and lipids (fats) in individual cells could help health professionals target more effective treatments for diseases such as tuberculosis (TB).

17 Feb 2023

Ferroptosis could be the key to making effective immunotherapies against liver cancer

Iron-dependent cell death (ferroptosis) is a type of programmed cell death by means of which the body kills off diseased, defective or superfluous cells.

17 Feb 2023

Researchers use the drug fasudil to reverse two key symptoms of schizophrenia

A team from Nagoya University in Japan used the drug fasudil to reverse two common symptoms associated with schizophrenia: reduced density of pyramidal neurons and cognitive dysfunction associated with methamphetamine treatment.

17 Feb 2023

UTA researchers discover how to identify which brain cells lead to epileptic episodes in children

A University of Texas at Arlington bioengineer and his doctoral student have discovered how to identify which brain cells lead to epileptic episodes in children.

17 Feb 2023

Drugs News and Research

Long-acting antiretroviral treatment may improve outcomes in underserved HIV patients

Researchers reveal the metabolic reactions upon activating Akt2 enzyme

New approach to pain management can reduce opioid use after urethroplasty

Two new zebrafish models for studying the most common cause of Leigh syndrome developed

Life Sciences Innovator Category Winner 2023

Oxford-Harrington Rare Disease Centre hosts virtual event in honor of the upcoming Rare Disease Day

Ethnic and regional minorities derive at least as much cardiovascular benefit from lipid-lowering therapies

A law was meant to free sick or aging inmates. Instead, some are left to die in prison.

HKU research advances understanding of the fundamental biological processes of gene regulation

Use of dapivirine vaginal ring during third trimester of pregnancy poses no safety concerns

Structure of DREADD designer receptor could pave the way for creating next generation tools

Ketamine appears to hold promise in treating cocaine-use disorders

Study finds fiftyfold increase in U.S. methamphetamine mortality rate between 1999 and 2021

Activating or deactivating drugs with the help of light

Utilizing CRISPR to discover new therapy options for COPD

Are SGLT2 inhibitors the next blockbuster drug?

New method to measure drugs and lipids in cells could lead to effective treatments for diseases

Ferroptosis could be the key to making effective immunotherapies against liver cancer

Researchers use the drug fasudil to reverse two key symptoms of schizophrenia

UTA researchers discover how to identify which brain cells lead to epileptic episodes in children

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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