Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

SMER28 can reduce beta-amyloid accumulation in patients with Alzheimer's disease

If you can't stop the beta-amyloid protein plaques from forming in Alzheimer's disease patients, then maybe you can help the body rid itself of them instead. At least that's what scientists from New York were hoping for when they found a drug candidate to do just that.

8 Mar 2011

Study: Moderate drinking can reduce risk of dementia even among older adults

3202 German individuals attending general practitioners , who were free of dementia were studied at baseline, were followed up 1.5 years and 3 years later by means of structured clinical interviews including detailed assessment of current alcohol consumption and DSM-IV dementia diagnoses.

8 Mar 2011

Researchers find new strategy for long-term care of seniors

America's 75 million aging adults soon will face decisions about where and how to live as they age. Current options for long-term care, including nursing homes and assisted-living facilities, are costly and require seniors to move from place to place.

8 Mar 2011

North Shore-LIJ launches new prenatal quality initiative

Having a child is a life event that is equal parts magic and fear. Will the baby be healthy? Will labor and delivery pose challenges? Are there ways to reduce the risk for adverse events? Hospital obstetrical units face these questions round-the-clock.

8 Mar 2011

hUCBs and MenSCs transplant may offer future therapeutic benefit for AD, stroke, ALS

Transplanting stem cells derived from umbilical cord blood cells and menstrual blood cells may offer future therapeutic benefit for those suffering from stroke, Alzheimer's disease, and amyotrophic lateral sclerosis, says a team of neuroscience researchers from the University of South Florida's Department of Neurosurgery and Brain Repair and collaborators from three private-sector research groups, Saneron CCEL Therapeutics, Inc., Tampa, FL, Cryo-Cell International, Inc., Oldsmar, FL, and Cryopraxis, Cell Praxis, BioRio, Rio de Janeiro, Brazil.

8 Mar 2011

Prevalence of bipolar disorder

Bipolar disorder is a psychiatric disorder that swings between depression and mania. It strikes early and can cause lifelong disability. Reports show that it is chronically undertreated in many low-income countries.

7 Mar 2011

Prestige Assisted Living at Sierra Vista to host educational speaker series that explores memory care issues

How can caregivers recognize the difference between normal age-related memory lapses and memory loss related to dementia? Prestige Assisted Living at Sierra Vista will host an educational speaker series that offers insight into memory care issues, beginning in March.

5 Mar 2011

Novel gene therapy can promote removal of amyloid plaques and prevent Alzheimer's disease

Gene therapy that boosts the ability of brain cells to gobble up toxic proteins prevents development of Alzheimer's disease in mice that are predestined to develop it, report researchers at Georgetown University Medical Center. They say the treatment - which is given just once - could potentially do the same in people at the beginning stages of the disease.

5 Mar 2011

Longer looks: Best health policy picks from thought-provoking publications

Every Thursday, KHN's Jessica Marcy compiles this selection of interesting perspectives, from a variety of publications, on health care in America.

4 Mar 2011

Boston Blades' new team to raise money, awareness for Alzheimer's research

The Alzheimer's Association, Massachusetts/New Hampshire Chapter and the exciting new women's hockey team, the Boston Blades, announced they are teaming up to raise money and awareness for Alzheimer's research.

4 Mar 2011

Researchers transform human embryonic stem cell into neuron that dies early in Alzheimer's disease

Northwestern Medicine researchers for the first time have transformed a human embryonic stem cell into a critical type of neuron that dies early in Alzheimer's disease and is a major cause of memory loss.

4 Mar 2011

New study finds liver instead of the brain as source of Alzheimer’s plaques

Unexpected results from a Scripps Research Institute and ModGene, LLC study could completely alter scientists' ideas about Alzheimer's disease—pointing to the liver instead of the brain as the source of the "amyloid" that deposits as brain plaques associated with this devastating condition. The findings could offer a relatively simple approach for Alzheimer's prevention and treatment.

4 Mar 2011

Lactate plays critical role in formation of long-term memory

Researchers from Mount Sinai School of Medicine have found that lactate, a type of energy fuel in the brain, plays a critical role in the formation of long-term memory. These findings have important implications for common illnesses like Alzheimer's disease, other neurodegenerative disorders, aging-related memory impairment and diabetes. The research is published in the March 4th issue of the journal Cell.

4 Mar 2011

Efficiency of brain function depends on family's genetic makeup

How well our brain functions is largely based on our family's genetic makeup, according to a University of Melbourne led study.

4 Mar 2011

Neuropathologist receives AAN Potamkin Prize for Alzheimer's disease research

The American Academy of Neurology has awarded the 2011 Potamkin Prize to Dennis Dickson, M.D., a neuropathologist at Mayo Clinic in Florida and the Robert E. Jacoby Professor for Alzheimer's Disease Research.

3 Mar 2011

Neurodegenerative Disease Management – meeting the challenge of neurodegenerative diseases

Future Medicine Ltd has today announced the launch of Neurodegenerative Disease Management – a new bimonthly title addressing all the latest trends in the field, from R&D through to clinical application and management, presenting research, findings, analysis and commentaries from experts around the world.

3 Mar 2011

Omeros identifies orphan GPCR compounds associated to pancreatic cancer, cognitive disorders

Omeros Corporation today announced that it has identified compounds that interact selectively with two orphan G protein-coupled receptors linked to pancreatic cancer and cognitive disorders.

3 Mar 2011

ITI, Takeda collaborate to develop and commercialize PDE1 inhibitors for schizophrenia

Intra-Cellular Therapies, Inc. ("ITI") and Takeda Pharmaceutical Company Limited, today announced that they have entered into an exclusive collaboration to develop and commercialize selective phosphodiesterase type 1 (PDE1) inhibitors, discovered by ITI, for the treatment of cognitive impairment associated with schizophrenia. This agreement is targeted worldwide, but ITI has retained the option to co-promote with Takeda in the United States.

3 Mar 2011

Ibuprofen may protect against development of Parkinson's disease

New research suggests that ibuprofen may offer protection against developing Parkinson's disease, according to one of the largest studies to date investigating the possible benefits of the over-the-counter drug on the disease. The study is published in the March 2, 2011, online issue of Neurology®, the medical journal of the American Academy of Neurology.

2 Mar 2011

BigThink.com launches breakthroughs: Discussion highlighting cutting-edge cancer research

Everyone knows someone that has been touched by cancer. Over one and a half million Americans will be diagnosed with some form of cancer in 2011, and more than 560,000 will die from the disease, accounting for 1 out of every 5 deaths.

2 Mar 2011

Alzheimer's Disease News and Research

Further Reading

SMER28 can reduce beta-amyloid accumulation in patients with Alzheimer's disease

Study: Moderate drinking can reduce risk of dementia even among older adults

Researchers find new strategy for long-term care of seniors

North Shore-LIJ launches new prenatal quality initiative

hUCBs and MenSCs transplant may offer future therapeutic benefit for AD, stroke, ALS

Prevalence of bipolar disorder

Prestige Assisted Living at Sierra Vista to host educational speaker series that explores memory care issues

Novel gene therapy can promote removal of amyloid plaques and prevent Alzheimer's disease

Longer looks: Best health policy picks from thought-provoking publications

Boston Blades' new team to raise money, awareness for Alzheimer's research

Researchers transform human embryonic stem cell into neuron that dies early in Alzheimer's disease

New study finds liver instead of the brain as source of Alzheimer’s plaques

Lactate plays critical role in formation of long-term memory

Efficiency of brain function depends on family's genetic makeup

Neuropathologist receives AAN Potamkin Prize for Alzheimer's disease research

Neurodegenerative Disease Management – meeting the challenge of neurodegenerative diseases

Omeros identifies orphan GPCR compounds associated to pancreatic cancer, cognitive disorders

ITI, Takeda collaborate to develop and commercialize PDE1 inhibitors for schizophrenia

Ibuprofen may protect against development of Parkinson's disease

BigThink.com launches breakthroughs: Discussion highlighting cutting-edge cancer research

Aneuro: A Year of Neuroscience in Review eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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