DNA Damage News and Research

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Excess EXO1 protein may drive cancer DNA damage and treatment response

When it comes to cancer, tumor suppressor genes are usually thought of as the "good guys." These genes make proteins that protect and repair DNA in cells.

21 May 2026

Methylene blue enhances hair follicle stem cell regeneration under stress

A new research paper was published in Volume 18 of Aging-US on May 5, 2026, titled "Methylene blue protects hair follicle stem cells from oxidative and metabolic stress to enhance hair regeneration."

19 May 2026

Sensory nerve signals found to block lung cancer immunotherapy

Researchers at the Francis Crick Institute have revealed that sensory nerve signals interfere with the immune system's response to lung cancer.

19 May 2026

Cancer-driving MYC protein also helps tumors repair damaged DNA

A protein best known for driving cancer growth also helps damaged tumor cells survive by repairing their DNA, according to a new study that could influence how some cancers are treated.

17 May 2026

New mechanism to enhance precision in cancer drug development

Researchers at The University of Texas Medical Branch (UTMB) have identified how a key enzyme called ATR protects DNA from breaking when cells copy damaged genetic material, a discovery that could affect how certain cancer drugs are developed.

15 May 2026

Study explains how APOE2 gene protects the brain against Alzheimer's disease

People who carry the APOE2 version of the apolipoprotein E gene are more likely to live to advanced age and are partly protected against Alzheimer's disease, but scientists have struggled to explain why.

13 May 2026

Molecular switch in mice links energy burning and bone health

Scientists' discovery of a molecular "switch" that activates an energy‑burning pathway in mice has the potential to lead to new treatments for bone disease.

11 May 2026

Urges for cardiologists to screen patients for UPF intake

The European Society of Cardiology identifies ultra-processed foods as a key cardiovascular risk, urging a shift in dietary guidelines for better heart health.

11 May 2026

Chromosome abnormalities may help cancer cells resist treatment and spread

A new study led by NYU Langone Health researchers found that cancer cells are better able to resist treatments when they have an abnormal number of chromosomes, which are DNA strands wound up in bundles that control which genetic instructions are followed in each cell type.

7 May 2026

GADD45B promotes apoptosis in intestinal injury through DNA demethylation

Intestinal ischemia/reperfusion (I/R) injury is a common pathophysiological phenomenon that is widely present in various primary intestinal diseases and systemic critical illnesses, potentially leading to multiple organ dysfunction and failure, with high morbidity and mortality.

5 May 2026

How fast your face ages may predict cancer survival outcomes

The study links facial aging rates to cancer outcomes, suggesting a new prognostic tool that could personalize treatment and enhance patient survival.

1 May 2026

Study identifies protein essential for repairing damage after inflammation

Whenever there is a wound or infection, the body produces an inflammatory response. This is the body's first line of defense, and macrophages — cells of the innate immune system — play a key role: first, they help eliminate pathogens and other infectious agents, and then they trigger the mechanisms that repair the damage caused during the inflammatory process.

28 Apr 2026

New imaging method maps DNA replication forks with single-cell resolution

Researchers at The University of Texas MD Anderson Cancer Center have developed a new imaging method, known as RF-SIRF, that quantitatively detects and maps reversed DNA replication forks with single-cell resolution

28 Apr 2026

A new biological switch to slow atherosclerosis progression

A study by researchers at Baylor College of Medicine and collaborating institutions reveals a previously unrecognized way blood vessels can protect themselves from damage and slow the development of atherosclerosis. The findings, published in the Proceedings of the National Academy of Sciences, have implications for both vascular precision medicine and the safety of certain emerging cancer treatments.

28 Apr 2026

Hyperbaric oxygen therapy shows dual effects in glioblastoma treatment

Glioblastoma remains a highly challenging malignancy with a pronounced tendency for recurrence. The hypoxic microenvironment is a key contributor to its therapy resistance.

23 Apr 2026

Restoring gut microbiome may prevent liver cancer in mice

Restoring the gut microbiome to its youthful state may hold the key to slowing aging and preventing liver cancer, one of the fastest-growing cancers worldwide, according to a study to be presented at Digestive Disease Week (DDW) 2026.

23 Apr 2026

Global experts highlight new strategies to target human aging

A new meeting report was published in Volume 18 of Aging-US on April 6, 2026, titled "Toward actionable interventions in human aging (12th ARDD meeting, 2025)."

22 Apr 2026

Study explains the link between NDMA-contaminated water and childhood cancer

A new study from MIT suggests that a carcinogen that has been found in medications and in drinking water contaminated by chemical plants may have a much more severe impact on children than adults.

17 Apr 2026

Researchers discover how stress signals weaken the aging immune system

As we age, our ability to maintain healthy blood and a strong immune system gradually declines, largely because hematopoietic stem cells (HSCs), the cells responsible for producing all blood cell types, begin to lose their effectiveness. Normally, HSCs can both self-renew and generate a balanced mix of blood cells, but over time they produce fewer new cells, favor certain cells such as myeloid cells over lymphoid cells, and struggle to support a robust immune response.

16 Apr 2026

Aston University bioscientist receives £125,000 to investigate genetic reasons for neurodegeneration

Aston University bioscientist Dr John Reynolds has won a £125,000 Springboard grant from the Academy of Medical Sciences (AMS) for research into neurodegeneration caused by a rare genetic disease.

15 Apr 2026