Hypoxia News and Research

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Hypoxia is a condition in which there is a decrease in the oxygen supply to a tissue. In cancer treatment, the level of hypoxia in a tumor may help predict the response of the tumor to the treatment.

Diagnostic prognostic and therapeutic relevance of PIVKA-II in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality worldwide, particularly in regions with high hepatitis B virus prevalence.

24 Jan 2026

Bradycardia emerges as key clinical sign of xylazine-opioid overdose

Researchers have identified bradycardia-an abnormally low heart rate–as a symptom of xylazine-opioid overdose.

14 Jan 2026

Engineered vessels boost retinal organoid function, enabling advanced disease modeling

Until now, it has been difficult to maintain retinal ganglion cells deep inside organoids over extended periods. The supply of nutrients and oxygen in the densely packed tissues is limited, leading to cell death.

14 Jan 2026

HIF1 protein identified as key driver of tendon pain

Overuse of our tendons can cause painful medical conditions for which only limited treatment options exist. Researchers have now deciphered an important molecular mechanism that triggers these problems.

14 Jan 2026

New research decodes the bacterial “zip code” of colorectal cancer for prediction and survival

Bacterial communities in colorectal cancer reveal patterns linked to tumor genetics and patient outcomes, paving the way for personalized treatment strategies.

From BGI Genomics 9 Jan 2026

Nicotinic acid protects the liver from ischemia-reperfusion injury

In a new study published in Liver Research, a team of researchers in China discovered that nicotinic acid-a common form of vitamin B3-can dramatically reduce liver damage caused by ischemia-reperfusion injury (IRI), a major complication in liver surgery and transplantation.

5 Jan 2026

Study examines fairness of oxygen desaturation thresholds in sleep apnea diagnosis

Obstructive sleep apnea (OSA) is a common sleep disorder in the U.S. affecting tens of millions, with estimates ranging from 25 to more than 80 million adults.

17 Dec 2025

Study shows iCTG improves perinatal outcomes in resource-constrained settings

Ninety-nine percent of global newborn deaths occur in low- and middle-income countries (LMICs), where pregnant women often struggle to access adequate fetal monitoring. In Tanzania, with 24 neonatal deaths per 1000 live births, a new wireless fetal heart rate monitoring technology is showing promise in preventing newborn complications and deaths.

17 Dec 2025

Frog-derived bacteria offer dual-action anticancer effects and high safety

A research team of Prof. Eijiro Miyako at the Japan Advanced Institute of Science and Technology (JAIST) has discovered that the bacterium Ewingella americana, isolated from the intestines of Japanese tree frogs (Dryophytes japonicus), possesses remarkably potent anticancer activity. This groundbreaking research has been published in the international journal Gut Microbes.

16 Dec 2025

Scientists map how cinnamon’s bioactives interact with cancer signaling

This review synthesizes preclinical evidence showing that cinnamon-derived compounds can modulate inflammation, oxidative stress, apoptosis, and angiogenesis through multiple cancer-related signaling pathways. While biologically plausible, the findings are largely limited to cell and animal models, underscoring the need for pharmacokinetic, safety, and clinical validation.

15 Dec 2025

External signals control oncolytic bacteria for precise cancer therapy delivery

Engineered oncolytic bacteria have emerged as a promising therapeutic platform for precision cancer treatment, offering tumor-specific colonization, immune activation, and controllable therapeutic delivery. This review summarizes recent advances in the design and application of synthetic biological strategies that enhance bacterial precision, safety, and efficacy in tumor therapy.

13 Dec 2025

Settling the creatine safety debate

Research confirms creatine's safety, highlighting misinformation and low-quality supplements as primary concerns over cancer and kidney health risks.

3 Dec 2025

Treating sleep apnea can lower Parkinson’s disease risk

Researchers report that obstructive sleep apnea increases the risk of Parkinson’s disease however, this risk can be attenuated by positive airway pressure.

1 Dec 2025

Fu's subcutaneous needling offers a safe non-pharmacological therapy for muscle-related pain

Chronic muscle tension is a common underlying factor in many pain disorders, causing reduced arterial blood flow, tissue hypoxia, and the release of inflammatory mediators.

28 Nov 2025

Marine bacterium shows powerful therapeutic effects against colorectal cancer

A research team led by Professor Eijiro Miyako at the Graduate School of Advanced Science and Technology, Japan Advanced Institute of Science and Technology (JAIST), has discovered that the marine bacterium Photobacterium angustum demonstrates remarkable therapeutic efficacy against colorectal cancer.

21 Nov 2025

Breast cancer cells use a molecular switch to survive stress

Cells are regularly faced with environmental stresses that may damage or destroy them. To survive, they quickly adjust their gene expression to protect themselves.

17 Nov 2025

Exosomes identified as key mediators in obstructive sleep apnea and its comorbidities

Obstructive sleep apnea (OSA), a global public health issue marked by repeated upper airway collapse during sleep, is tied to diverse diseases-from cardiovascular conditions to cancer.

12 Nov 2025

The caffeine conundrum in rapid depression treatments

Perhaps the most intriguing implication of recent breakthrough research lies in an unexpected connection: the most rigorous mechanistic dissection of rapid antidepressant action identifies adenosine as the critical mediator, yet adenosine receptors are the primary target of caffeine, the world's most widely consumed psychoactive substance.

11 Nov 2025

New precision therapies reshape the future of pancreatitis treatment

Pancreatitis remains a major global health burden, encompassing acute pancreatitis (AP), chronic pancreatitis (CP), and autoimmune pancreatitis (AIP).

11 Nov 2025

New review illuminates the intricate connections between gut microbiota and sleep regulation

A comprehensive review published today in Brain Medicine illuminates the intricate connections between gut microbiota and sleep regulation, establishing the microbiota-gut-brain axis as a critical pathway in understanding and potentially treating sleep disorders.

4 Nov 2025

Hypoxia News and Research

Further Reading

Diagnostic prognostic and therapeutic relevance of PIVKA-II in hepatocellular carcinoma

Bradycardia emerges as key clinical sign of xylazine-opioid overdose

Engineered vessels boost retinal organoid function, enabling advanced disease modeling

HIF1 protein identified as key driver of tendon pain

New research decodes the bacterial “zip code” of colorectal cancer for prediction and survival

Nicotinic acid protects the liver from ischemia-reperfusion injury

Study examines fairness of oxygen desaturation thresholds in sleep apnea diagnosis

Study shows iCTG improves perinatal outcomes in resource-constrained settings

Frog-derived bacteria offer dual-action anticancer effects and high safety

Scientists map how cinnamon’s bioactives interact with cancer signaling

External signals control oncolytic bacteria for precise cancer therapy delivery

Settling the creatine safety debate

Treating sleep apnea can lower Parkinson’s disease risk

Fu's subcutaneous needling offers a safe non-pharmacological therapy for muscle-related pain

Marine bacterium shows powerful therapeutic effects against colorectal cancer

Breast cancer cells use a molecular switch to survive stress

Exosomes identified as key mediators in obstructive sleep apnea and its comorbidities

The caffeine conundrum in rapid depression treatments

New precision therapies reshape the future of pancreatitis treatment

New review illuminates the intricate connections between gut microbiota and sleep regulation

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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