Morphology News and Research

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Lab-grown corticospinal neurons offer new models for ALS and spinal injuries

Researchers have developed a way to grow a highly specialized subset of brain nerve cells that are involved in motor neuron disease and damaged in spinal injuries.

29 Jan 2026

PFOA exposure disrupts hormone signaling and impairs embryo implantation in mice

A new experimental study has found that perfluorooctanoic acid (PFOA), a widely used industrial chemical, can interfere with key biological processes required for successful embryo implantation, raising concerns about its potential impact on female fertility.

27 Jan 2026

Dual-responsive nanodelivery system enhances immunotherapy efficacy in metastatic bladder cancer

Metastatic urothelial carcinoma has a poor prognosis: ~50% of muscle-invasive bladder cancer progresses to metastasis, and the 5-year survival for advanced/metastatic disease is <10%.

24 Jan 2026

Silica nanomatrix enhances immunotherapy for solid tumors

Cancer has long remained a leading cause of death worldwide and in Hong Kong, accounting for 30% of all disease-related deaths in the city in 2025. While chemotherapy remains a major treatment modality, its side effects and the risk of relapse challenges for patients.

30 Dec 2025

Large-scale study reveals joint functional and structural patterns of brain aging

Healthy aging induces parallel changes in brain functional activity and structural morphology, yet the interplay between these changes remains unclear.

18 Dec 2025

Hydrogel-based treatment achieves innervation and pulp-dentin regeneration

The dental pulp is susceptible to microbial infection, which often results in inflammation, necrosis, and defects in the pulp-dentin complex. Traditional treatment strategies suffer from multiple limitations and do not promote neural regeneration.

16 Dec 2025

Half of hospitalized COVID-19 patients developed long COVID

Research from Thailand shows high long COVID prevalence in hospitalized patients, with severe illness increasing risk and vaccination offering protection.

15 Dec 2025

Distinct transcriptomic profiles guide early development of maxillary and mandibular teeth

The interaction between genetics and tissue environment shapes how individual teeth form in different regions of the jaw.

12 Dec 2025

New findings show why the human intestine uniquely presents gluten to T cells

Human intestinal M cells function as dendritic cell-like antigen-presenting cells, displaying constitutive MHC-II activity and specialized machinery for processing gluten. Their ability to deamidate and present gliadin peptides positions them as key initiators of immune responses relevant to coeliac disease.

11 Dec 2025

AI turns routine pathology slides into powerful maps of the tumor immune landscape

A large study shows that routine H&E pathology slides contain rich spatial proteomic signals that can be decoded by AI to model the tumor immune microenvironment at population scale. By generating virtual multiplex immunofluorescence images, GigaTIME enables pan-cancer discovery of immune patterns linked to invasion stage, survival, and genomic alterations.

10 Dec 2025

New technique helps understand how bacterial shapes contribute to disease

Scientists have long known that bacteria come in many shapes and sizes, but understanding what those differences mean has remained a major challenge, especially for species that can't be grown in the lab. Now, a new study led by Nina Wale, an Assistant Professor in MSU's Department of Microbiology, Genetics, & Immunology, introduces a groundbreaking method that could change how researchers study bacterial diversity.

1 Dec 2025

Machine learning tool identifies compounds that induce cancer cells into senescence

A new research paper featured on the cover of Volume 17, Issue 11 of Aging-US was published on October 30, 2025, titled "SAMP-Score: a morphology-based machine learning classification method for screening pro-senescence compounds in p16 positive cancer cells."

1 Dec 2025

Novel nanowire platform mimics brain tissue to study astrocytes

Scientists have engineered a nanowire platform that mimics brain tissue to study astrocytes, the star-shaped cells critical for brain health, for the first time in their natural state.

24 Nov 2025

Generative AI tool enhances accuracy in detecting abnormal blood cells

An AI tool that can analyze abnormalities in the shape and form of blood cells, and with greater accuracy and reliability than human experts, could change the way conditions such as leukemia are diagnosed.

19 Nov 2025

Redefining control and consistency in anaerobic microbiome workflows

Explore how smart automation enables precise, reproducible workflows in anaerobic microbiome research, improving accuracy and experimental control.

From Molecular Devices UK Ltd 5 Nov 2025

Football hits leave lasting brain changes

Recent MRI research reveals how repeated football head impacts reshape brain structures, offering insights into chronic traumatic encephalopathy (CTE) risk.

30 Oct 2025

Subtle brain changes in football players could predict the risk of chronic traumatic encephalopathy

Brain scans from American football players reveal subtle differences in the brain's outer grooves when compared to scans from otherwise healthy men who never played contact or collision sports, a new study shows.

28 Oct 2025

Revolutionizing blood diagnostics with real-time QPM technology

Blood tests are among the most common tools in medicine. Scientists are working to make blood cell imaging faster and more intuitive so that doctors can make fast and accurate diagnostic decisions.

24 Oct 2025

Review reveals how paternal lifestyle shapes sperm epigenetics and offspring health

A new review in Clinical Epigenetics synthesises growing evidence that paternal lifestyle and environmental exposures such as diet, obesity, smoking, endocrine-disrupting chemicals, and stress alter sperm epigenetic marks (DNA methylation, histone retention, and small non-coding RNAs).

17 Oct 2025

Study uncovers mechanisms regulating the cell’s primary cilia

Prof. Dr. Elif Nur Fırat Karalar from Koç University's Department of Molecular Biology and Genetics and her team have uncovered the molecular mechanisms responsible for regulating a structure that plays a critical role in how cells communicate with their environment.

16 Oct 2025