Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Scientists uncover cellular mechanism behind congenital heart defects

Congenital heart disease affects approximately two in every 100 newborns globally. But why do they occur?

4 Aug 2026

New 3D brain tissue model accelerates Alzheimer's drug development

How can Alzheimer's research be made faster, better, and more effective? After decades of intensive research worldwide and despite recent therapeutic advances, scientists have not managed to fully arrest the progress of the disease.

4 Aug 2026

Blocking xenophagocytosis improves donor cell survival and interspecies organ generation

Xenophagocytosis is a natural immune process that limits interspecies organ generation by eliminating living donor cells, report researchers at Institute of Science Tokyo, Japan.

31 Jul 2026

TRF2 protein preserves muscle stem cell identity and regeneration

A protein best known for protecting the ends of chromosomes also helps muscle stem cells preserve their identity and repair damaged tissue, according to a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

31 Jul 2026

New mechanism linked to septic heart injury protection uncovered

Sepsis triggers widespread inflammation, circulatory failure and metabolic stress, and cardiac dysfunction is a common complication associated with sharply poorer outcomes.

31 Jul 2026

New stem cell vesicles accelerate diabetic wound healing

Diabetic foot ulcers are among the most serious complications of diabetes because prolonged inflammation, poor circulation, and defective angiogenesis can leave wounds open for months and increase the risk of infection and amputation.

31 Jul 2026

QUANTUM trial tests immune-targeting approach for primary plasma cell leukemia

The Alliance for Clinical Trials in Oncology today announced the activation of The QUANTUM Trial (Alliance A062401), a clinical study designed to test a novel, immune-targeting approach for patients newly diagnosed with primary plasma cell leukemia (PCL).

30 Jul 2026

NIH awards $2.4 million to study how maternal viral infections reprogram fetal immune development

The National Institute of Allergy and Infectious Diseases of the National Institutes of Health has awarded a new, five-year $2.4 million R01 grant to Dr. Jiahui Ding, assistant professor of obstetrics and gynecology at the Wayne State University School of Medicine's C.S. Mott Center for Human Growth and Development, to support research that aims to uncover how viral infections during pregnancy reprogram the developing immune system of the fetus, influencing susceptibility to infectious diseases throughout life.

29 Jul 2026

Researchers find potential pathway to improve glioblastoma treatment

New research published in Neuro-Oncology gives a glimpse at promising discoveries that could help shape the future of glioblastoma treatment and patient outcomes.

29 Jul 2026

Small changes in one heart protein cause distinct cardiomyopathies

Cardiomyopathies are a group of mostly hereditary, rare heart diseases in which the structure of the heart muscle tissue is impaired.

29 Jul 2026

Cell junction proteins regulate stem cell signaling and tissue homeostasis

In many animal tissues, stem cells continually divide to create new cells that replace old or damaged ones. However, this capacity requires strict regulation, as uncontrolled stem cell proliferation can disrupt tissue homeostasis and contribute to tumorigenesis.

28 Jul 2026

Study identifies simvastatin as promising adjuvant for periodontitis treatment

Porphyromonas gingivalis can evade antibiotics by invading host cells, contributing to recurrent periodontitis and persistent tissue damage.

26 Jul 2026

Researchers discover molecule to fight age-related muscle decline

Skeletal muscle is one of the first tissues to decline with age. This decline can lead to weakness, scarring, fat accumulation inside muscle, and the loss of fast-twitch muscle fibers that are important for quick and powerful movements.

24 Jul 2026

Study reveals how DNA misfolding causes congenital heart disease

Congenital heart disease is the most common birth defect, affecting approximately 1 in 100 babies born each year. One of the many causes for this disorder is having only one functional copy of the gene TBX5, instead of two healthy copies, inherited from parents.

23 Jul 2026

Mass-producible immune cells fight solid human tumors in mice

Off-the-shelf and mass-producible immune cells fight solid human tumors engrafted into mice. The Kobe University development is a significant contribution towards faster and cheaper cancer immunotherapy.

23 Jul 2026

Senolytic drugs rejuvenate blood stem cells in sickle cell disease

Sickle cell disease causes premature aging of blood stem cells, which scientists may be able to address with a special class of drugs, according to a new study from St. Jude Children's Research Hospital.

22 Jul 2026

New AI score enhances monitoring of myelodysplastic neoplasms

Weill Cornell Medicine investigators have developed a new AI-based method to assess patients with a form of blood cancer called myelodysplastic neoplasms.

20 Jul 2026

Scientists discover hidden cell network driving rapid intestinal renewal

Your intestine completely rebuilds its inner lining every few days—one of the fastest renewal processes in the human body.

20 Jul 2026

Researchers use canine iPSCs to generate red blood cell-like cells

Blood transfusions are crucial in human and veterinary medicine, yet human blood reserves are in constant need of donors while blood bank systems in veterinary care are nearly non-existent.

19 Jul 2026

Single-cell analysis identifies key regulators of cancer metastasis

By analyzing individual cancer cells, researchers from the Université Libre de Bruxelles (ULB) discovered the transcriptional regulators governing EMT in tumors and identified key master regulators that control metastasis, unraveling novel therapeutic vulnerabilities to block metastatic dissemination.

16 Jul 2026