Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Blood-brain barrier dysfunction and inflammation linked to Down syndrome Regression Disorder

A new research study led by Jonathan D. Santoro, MD, Director of the Neuroimmunology Program at Children's Hospital Los Angeles, shows evidence of dysfunction of the blood-brain barrier and inflammation in the central nervous system in individuals with Down syndrome Regression Disorder (DSRD).

14 Mar 2025

New scientific clue could unlock key cellular pathway leading to neurodegenerative diseases

In Nature Neuroscience, UConn School of Medicine researchers have revealed a new scientific clue that could unlock the key cellular pathway leading to devastating neurodegenerative diseases like Alzheimer's disease, and the progressive damage to the brain's frontal and temporal lobes in frontotemporal degeneration (FTD) and the associated disease amyotrophic lateral sclerosis (ALS).

14 Mar 2025

University of Minnesota awarded NIH grant for Alzheimer's cell therapy development

A University of Minnesota research team was recently awarded a five-year, $3.8 million grant from the U.S. National Institutes of Health to develop a new cell therapy to combat Alzheimer's disease.

14 Mar 2025

Bioenergetic age could predict Alzheimer's disease risk

A person's "bioenergetic age"-or how youthfully their cells generate energy-might be a key indicator of whether they're at risk of developing Alzheimer's disease, new research from Weill Cornell Medicine shows.

14 Mar 2025

Groundbreaking stem cell therapy trial for Alzheimer's disease underway at UTHealth Houston

A stem cell therapy trial aimed at reducing neuroinflammation in patients with presymptomatic Alzheimer's disease is underway at UTHealth Houston.

14 Mar 2025

Portable system detects mild cognitive impairment in older adults

Mild cognitive impairment (MCI) can be an early indicator of Alzheimer's disease or dementia, so identifying those with cognitive issues early could lead to interventions and better outcomes.

13 Mar 2025

Study links Doomsday Clock to mortality and mental health

Since 1947, the Bulletin of the Atomic Scientists (BAS) has used the metaphor of the Doomsday Clock as a means of communicating how close the human species is to self-imposed annihilation, represented as midnight.

12 Mar 2025

Dementia risk higher among adults with HIV in Malawi

Adults living with HIV in Malawi are more than twice as likely to also have dementia compared to those without HIV, according to a new study by a team of US and Malawian researchers.

12 Mar 2025

Compound found in rosemary shows promise for Alzheimer's treatment

The herb rosemary has long been linked with memory: "There's rosemary, that's for remembrance," says Ophelia in Shakespeare's Hamlet. So it is fitting that researchers would study a compound found in rosemary and sage-carnosic acid-for its impact on Alzheimer's disease.

10 Mar 2025

Understanding the role of LSD1 in cellular processes and disease

A new review highlights the pivotal role of LSD1 (lysine-specific demethylase 1) in regulating critical cellular processes and its implications for human diseases.

8 Mar 2025

Music-based therapy may benefit people living with dementia

A new Cochrane review has found evidence that music-based therapy may benefit people living with dementia, particularly by improving symptoms of depression.

7 Mar 2025

New brain mapping technique identifies cells vulnerable to Alzheimer's disease

Researchers from The University of Texas at Arlington and the University of California–San Francisco have used a new brain-mapping technique to identify memory-related brain cells vulnerable to protein buildup, a key factor in the development of Alzheimer's disease, an incurable, progressive brain disorder that slowly destroys memory and thinking skills.

6 Mar 2025

Study suggests boosting brain's immune cells could improve Alzheimer's treatment

For more than three decades, scientists have been racing to stop Alzheimer's disease by removing amyloid beta plaques - sticky clumps of toxic protein that accumulate in the brain.

6 Mar 2025

St. Jude researchers improve brain disease diagnosis with PET imaging and ALS drug

Positron emission tomography (PET) is a nuclear imaging technique used to diagnose conditions such as cancer. An innovative advance from scientists at St. Jude Children's Research Hospital is enhancing the technique's ability to check for signs of neurological disease.

6 Mar 2025

Menopausal hormone therapy may accelerate tau buildup in older women

A new study from Mass General Brigham researchers has found faster accumulation of tau-a key indicator of Alzheimer's disease-in the brains of women over the age of 70 who took menopausal hormone therapy (HT) more than a decade before.

5 Mar 2025

Higher menopausal symptom burden linked to cognitive decline and behavioral impairments

Women who exhibit more menopausal symptoms are more likely to later have poorer cognitive function and mild behavioral impairments – both markers of dementia.

5 Mar 2025

New approach to tau protein clearance offers hope for Alzheimer's treatment

USC Stem Cell scientists discover a new way to rid cells of toxic tau protein in a study involving mice and lab-grown human “mini-brains,” known as organoids.

5 Mar 2025

Exploring the role of subventricular zone in neural regeneration, neurodegenerative diseases

This recently published exploration into the subventricular zone (SVZ) highlights its critical role in neural regeneration, neurodegenerative diseases, and glioblastoma multiforme (GBM).

5 Mar 2025

Study explores gene interactions in Alzheimer's disease across brain regions

Alzheimer's disease (AD), a neurodegenerative disorder marked by amyloid plaque buildup and cognitive decline, remains a challenging condition to understand at the molecular level.

4 Mar 2025

Non-invasive 40Hz gamma stimulation could help fight Alzheimer’s

A decade after scientists in The Picower Institute for Learning and Memory at MIT first began testing whether sensory stimulation of the brain's 40Hz "gamma" frequency rhythms could treat Alzheimer's disease in mice, a growing evidence base supporting the idea that it can improve brain health-in humans as well as animals-has emerged from the work of labs all over the world.

3 Mar 2025

Alzheimer's Disease News and Research

Further Reading

Blood-brain barrier dysfunction and inflammation linked to Down syndrome Regression Disorder

New scientific clue could unlock key cellular pathway leading to neurodegenerative diseases

University of Minnesota awarded NIH grant for Alzheimer's cell therapy development

Bioenergetic age could predict Alzheimer's disease risk

Groundbreaking stem cell therapy trial for Alzheimer's disease underway at UTHealth Houston

Portable system detects mild cognitive impairment in older adults

Study links Doomsday Clock to mortality and mental health

Dementia risk higher among adults with HIV in Malawi

Compound found in rosemary shows promise for Alzheimer's treatment

Understanding the role of LSD1 in cellular processes and disease

Music-based therapy may benefit people living with dementia

New brain mapping technique identifies cells vulnerable to Alzheimer's disease

Study suggests boosting brain's immune cells could improve Alzheimer's treatment

St. Jude researchers improve brain disease diagnosis with PET imaging and ALS drug

Menopausal hormone therapy may accelerate tau buildup in older women

Higher menopausal symptom burden linked to cognitive decline and behavioral impairments

New approach to tau protein clearance offers hope for Alzheimer's treatment

Exploring the role of subventricular zone in neural regeneration, neurodegenerative diseases

Study explores gene interactions in Alzheimer's disease across brain regions

Non-invasive 40Hz gamma stimulation could help fight Alzheimer’s

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

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