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New computer algorithm offers a path toward pan-influenza and coronavirus vaccine

A novel computer algorithm that could create a broadly reactive influenza vaccine for swine flu also offers a path toward a pan-influenza vaccine and possibly a pan-coronavirus vaccine as well, according to a new paper published in Nature Communications.

2 Mar 2021

Novel dual-targeting drug could become a next-generation treatment for EBV-related cancers

A Hong Kong Baptist University-led research team has developed a novel drug which has the potential to become a next-generation treatment for cancers associated with Epstein-Barr virus (EBV).

2 Mar 2021

Scientists establish infection models for SARS-CoV-2 UK & South African variants

New research suggests Syrian golden hamsters could be a potentially useful preclinical model for testing vaccine immunity against the acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.17 and B.1.351 variant.

1 Mar 2021

Study could offer a new way to treat Type 1 and Type 2 diabetes

Blocking cell receptors for glucagon, the counter-hormone to insulin, cured mouse models of diabetes by converting glucagon-producing cells into insulin producers instead, a team led by UT Southwestern reports in a new study.

1 Mar 2021

Study demonstrates intricate relationship between Prpf19 and Exoc7 in inherited ataxias

Spinocerebellar ataxia type 3 (SCA3), also known as Machado-Joseph Disease (MJD), describes the most common form of dominantly inherited ataxia in many populations worldwide, including Hong Kong and mainland China.

1 Mar 2021

Study shows direct connection between the gut microbiome and Alzheimer's-like behavior

New research in mice published today in the journal Scientific Reports strengthens the growing scientific consensus regarding the role of the gut microbiome in neurodegenerative disorders including Alzheimer's disease.

25 Feb 2021

Insilico Medicine discovers novel preclinical candidate to address idiopathic pulmonary fibrosis

Insilico Medicine has demonstrated a breakthrough in Artificial Intelligence ("AI") and drug discovery -- linking together generative chemistry and biology for the first time -- to discover a novel preclinical candidate addressing idiopathic pulmonary fibrosis ("IPF") and be validated with multiple human cell and animal model experiments.

25 Feb 2021

Magnesium-based micromotors used to improve rheumatoid arthritis symptoms

Rheumatoid arthritis is a chronic inflammatory disorder marked by joint pain, swelling and damage. Although medications, such as steroids, anti-inflammatory drugs and immunosuppressants, can help slow joint destruction and relieve pain, they have side effects and aren't completely successful.

24 Feb 2021

Study identifies another reason to add mushrooms to American diet

The second study published in as many months has identified another reason to add more mushrooms to the recommended American diet.

24 Feb 2021

Sheep model may help address fertility problems in women

A Texas A&M AgriLife study with sheep may soon help address fertility problems in women, if it can discover ways to break the chain of generational transfer of polycystic ovary syndrome, PCOS -- one of the most common infertility disorders.

23 Feb 2021

Three decades-old antibiotics could offer an alternative to opioid-based painkillers

Three decades-old antibiotics administered together can block a type of pain triggered by nerve damage in an animal model, UT Southwestern researchers report.

23 Feb 2021

Scientists discover mechanism by which epithelial tumors cause maturation defects

Conducted on the fly Drosophila, the study shows that tumors caused by chromosomal instability delay entry into the adult phase.

23 Feb 2021

New rodent model helps identify pregnant women whose prior kidney injury also affects babies

Young pregnant women, who appear to have fully recovered from an acute injury that reduced their kidney function, have higher rates of significant problems like preeclampsia and low birthweight babies, problems which indicate their kidneys have not actually fully recovered.

22 Feb 2021

SARS-CoV-2 DNA vaccine tested in animal model

A team of experts has tested the immune responses elicited by mucosal homologous plasmid and a heterologous immunization strategy using a plasmid vaccine and a Modified Vaccinia Ankara (MVA) expressing SARS-CoV-2 spike (S) and nucleocapsid (N) antigens.

21 Feb 2021

Animal Model News and Research

New computer algorithm offers a path toward pan-influenza and coronavirus vaccine

Novel dual-targeting drug could become a next-generation treatment for EBV-related cancers

Scientists establish infection models for SARS-CoV-2 UK & South African variants

Study could offer a new way to treat Type 1 and Type 2 diabetes

Study demonstrates intricate relationship between Prpf19 and Exoc7 in inherited ataxias

Study shows direct connection between the gut microbiome and Alzheimer's-like behavior

Insilico Medicine discovers novel preclinical candidate to address idiopathic pulmonary fibrosis

Magnesium-based micromotors used to improve rheumatoid arthritis symptoms

Study identifies another reason to add mushrooms to American diet

Sheep model may help address fertility problems in women

Three decades-old antibiotics could offer an alternative to opioid-based painkillers

Scientists discover mechanism by which epithelial tumors cause maturation defects

New rodent model helps identify pregnant women whose prior kidney injury also affects babies

SARS-CoV-2 DNA vaccine tested in animal model

Biomedical engineer receives NASA grant to find ways to keep astronauts' bones strong in space

Researchers identify antibody that removes amyloid plaques without the risk of brain bleeds

Engineered peptide can reduce severe COVID-19 infection in humans

Researchers develop new tool for tackling disseminated intravascular coagulation

Scientists discover new immunotherapy target for malignant brain tumors

Study finds certain plasma microRNAs as diagnostic biomarkers for mild traumatic brain injury

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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