Autoimmune Disease News and Research

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Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.

New contrast agent improves MRI diagnosis of early liver fibrosis

A new compound has been invented to bind to liver cells that are in the early stages of damage, thus making it easier to pick them up using MRI (magnetic resonance imaging).

30 Oct 2019

MRI contrast agent enables early detection of liver disease

Researchers have developed a new MRI contrast dye that enables more accurate and safer detection of early-stage liver disease than currently approved agents.

30 Oct 2019

Dental health, diet may have an impact on psoriasis development and severity

Dental health and diet may have an impact on the development and severity of psoriasis, according to a study by dermatologists at The Ohio State University Wexner Medical Center. Psoriasis is a skin disease that causes thick, itchy patches of red skin with silvery scales and affects more than 8 million Americans.

29 Oct 2019

Gut microbiome is a reality in fetal life also

A study published in the Journal of Clinical Investigation shows that in both mice and humans, the fetal gut has its own microbiome, which is probably derived straight from the maternal organism.

24 Oct 2019

Unhealthy gut microbiome reduces brain synaptic pruning, impairs learning

A new study by Weill Cornell Medicine and Cornell University has come up with more explanations of how gut microbes communicate with the brain neurons. The study, published in the journal Nature on October 23, 2019, examined the brains of mouse models and found that when the gut microbiome is significantly reduced, there are changes in gene expression in the brain’s microglial cells.

24 Oct 2019

Study opens up array of options for developing treatments for cancer or autoimmune disorder

Immunologists at St. Jude Children's Research Hospital have discovered key biological switches that control regulatory T cells--specialized white blood cells that keep the immune system in check.

24 Oct 2019

Molecular processes underlying communication between gut microbes and brain cells revealed

New cellular and molecular processes underlying communication between gut microbes and brain cells have been described for the first time by scientists at Weill Cornell Medicine and Cornell's Ithaca campus.

23 Oct 2019

Findings point to potential interventions to improve preemie growth during high risk pregnancy

A study in humans and mice demonstrated that a fetus has its own microbiome, or communities of bacteria living in the gut, which are known to play important roles in the immune system and metabolism.

23 Oct 2019

Novel noninvasive imaging technique can provide information about thyroid disorders

A combination of multispectral optoacoustic tomography (MSOT) and ultrasound has been used to noninvasively characterize a range of thyroid disorders, according to new research published in the October issue of The Journal of Nuclear Medicine.

23 Oct 2019

New treatment shows promise to reverse celiac disease

Results of a new phase 2 clinical trial using technology developed at Northwestern Medicine show it is possible to induce immune tolerance to gluten in individuals with celiac disease. The findings may pave the way for treated celiac patients to eventually tolerate gluten in their diet.

22 Oct 2019

Research finds lower bone density among adults with undiagnosed celiac disease

Research by George Mason University College of Health and Human Services found that adults who likely had undiagnosed celiac disease had lower bone density than the adults without UCD, although they consumed more calcium and phosphorous.

17 Oct 2019

Rotavirus plays role in development of type 1 diabetes

A new article published in the journal PLOS Pathogens on October 10, 2019, claims that the common rotavirus may be responsible for the occurrence of type 1 diabetes, a form of diabetes which occurs in children and is due to destruction of the pancreatic islet cells that produce the hormone insulin to normalize blood glucose levels.

13 Oct 2019

Rotavirus infection may play a role in type 1 diabetes development

Rotavirus infection may play a role in the development of type 1 diabetes, according to a front matter article published October 10 in the open-access journal PLOS Pathogens by Leonard C. Harrison of the University of Melbourne in Australia, and colleagues.

From PLOS ONE 10 Oct 2019

Scientists show how protein Ikaros orchestrates fine balance to control autoimmunity

The immune system relies on B cells and their ability to make antibodies against an extremely broad range of pathogens. This broad responsiveness bears some risk, as B cells can also turn against healthy tissue - a phenomenon called autoimmunity.

8 Oct 2019

GW researchers to study the underlying pathophysiology of myasthenia gravis

The National Institutes of Health awarded a research team at the George Washington University $7.8 million to establish a rare disease network for myasthenia gravis. The network, which will be part of 25 established NIH Rare Diseases Clinical Research Networks, will include basic and clinical investigators, patient advocacy groups, and biotechnology and pharmaceutical companies working together to enhance therapeutic development for this rare disease.

4 Oct 2019

Clinical trial to evaluate efficacy and safety of new treatment for giant cell arteritis

An international, multicenter phase II clinical trial is evaluating the efficacy and safety of mavrilimumab co-administered with a 26-week corticosteroid taper in patients with giant cell arteritis.

26 Sep 2019

Arthritis drug could be used to treat lichen planus skin rash

Constant itchy, painful bumps, scaly arms and legs, and damaged nails make lichen planus an inflammatory skin disease that's both frustrating and painful for patients trying to keep their quality of life.

26 Sep 2019

Study finds nearly one in three patients with lupus uses prescription opioids for pain

Although there is little evidence that opioids effectively reduce pain from rheumatic diseases, a new study finds nearly one in three patients with lupus uses prescription opioids, often lasting longer than a year.

26 Sep 2019

Improving care and educational outreach for lupus patients

A new grant will allow MUSC doctors and researchers to test several ideas for improving care and outreach to people with lupus or at risk of developing the autoimmune disease.

17 Sep 2019

Gut bacterial changes influence lupus treatment results in pregnancy

The course of pregnancy, like that of true love, doesn’t always run smooth when you have lupus, correctly called systemic lupus erythematosus (SLE). This autoimmune disease is an occasionally violent, occasionally subdued, chronic inflammation that constantly smolders within multiple tissues in the body.

16 Sep 2019