Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Using genomics to restore degraded ecosystems

The monumental global task to restore degraded ecosystems will need to include sophisticated technologies such as environmental DNA monitoring to understand and support the recovery of complex biospheres, international researchers say.

27 Jun 2022

Rensselaer scientists secure $3.5 million grant to develop a low-dose, oral COVID antiviral drug

Rensselaer Polytechnic Institute researchers Gaetano Montelione and Christopher Cioffi will use a five-year, $3.5 million grant from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, to develop a low-dose, oral COVID antiviral drug that can be administered at home.

27 Jun 2022

Researchers discover two important novel aspects of APOE4 gene in Alzheimer's patients

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia, affecting more than 5.8 million individuals in the U.S.

23 Jun 2022

An integrated molecular diagnostic approach for detecting SARS-CoV-2 variants

Researchers developed an integrated approach combining NGS, molecular barcoding, machine learning, and bioinformatics to enable high-throughput detection of SARS-CoV-2 variants.

23 Jun 2022

Potential SARS-CoV-2 antivirals based on host miRNAs

A recent research paper posted to the bioRxiv* preprint server demonstrated micro ribonucleic acids (miRNAs) as potential antiviral options against various coronaviruses (CoVs), including severe acute respiratory syndrome CoV 2 (SARS-CoV-2).

21 Jun 2022

SARS-CoV-2 variant-specific polymerase chain reaction assay for SARS-CoV-2 genomic surveillance

Researchers reported on the misclassification of the SARS-CoV-2 Omicron BA.1 subvariant as Omicron BA.2 subvariant in an automated variant-specific polymerase chain reaction analysis.

17 Jun 2022

New approach to quantify tumor-specific total mRNA levels from patient tumor samples

Researchers at The University of Texas MD Anderson Cancer Center have developed a new approach to quantify tumor-specific total mRNA levels from patient tumor samples, which contain both cancer and non-cancer cells.

14 Jun 2022

New machine learning algorithm finds a gene signature characteristic of tumors

How do cancer cells differ from healthy cells? A new machine learning algorithm called "ikarus" knows the answer, reports a team led by MDC bioinformatician Altuna Akalin in the journal Genome Biology. The AI program has found a gene signature characteristic of tumors.

10 Jun 2022

Abundance of Lactobacillus crispatus linked to lower risk of preterm birth

Globally, preterm birth complications are the leading cause of death for children under the age of 5. Not everyone faces the same risk, though: In the United States, roughly 10% of pregnancies lead to preterm birth, but for Black women, that likelihood is 14%.

10 Jun 2022

Genomic analysis provides a deeper understanding of DCIS biology

A new study led by the global Cancer Grand Challenges PRECISION team, including researchers from The University of Texas MD Anderson Cancer Center, shifts the long-held belief that all invasive breast cancers following ductal carcinoma in situ (DCIS) arise from the original DCIS lesion.

9 Jun 2022

Discovery may lead to new treatments to reduce inflammation in vitiligo disease

A new study, led by researchers from the University of California, Irvine, reveals the unique cell-to-cell communication networks that can perpetuate inflammation and prevent repigmentation in patients with vitiligo disease.

7 Jun 2022

Lack of diversity in genomic research could deprive Africans of life-changing care for chronic diseases

The lack of diversity in genomic research could mean Africans are missing out on potential life-changing care for chronic health disorders, according to a new study published in Nature Medicine.

3 Jun 2022

A system for detecting emerging SARS-CoV-2 variants

An article published in the journal Nature Medicine examines the unpredictable evolution of the ongoing COVID-19 pandemic.

2 Jun 2022

Aerobic exercise amplifies the effects of immunotherapy to reduce pancreatic tumor growth

Aerobic exercise reprograms the immune system to reduce pancreatic tumor growth and amplify the effects of immunotherapy, a new study finds.

2 Jun 2022

New study uncovers the impact of genetic mutations on lifelong blood cell production

New research has uncovered how genetic mutations hijack the production of blood cells in different periods of life.

1 Jun 2022

Exposure to traffic-related air pollutants linked with pregnancy complications

A new study in mice by UCLA scientists reveals how exposure to traffic-related air pollutants causes cellular changes in the placenta that can lead to pregnancy complications and affect the health of both mother and offspring.

31 May 2022

Researchers gain understanding of biosynthetic mechanisms for producing cyanobacterin

Researchers in the groups of Prof. Tobias Gulder from TU Dresden and Prof. Tanja Gulder from Leipzig University have succeeded in understanding the biosynthetic mechanisms for the production of the natural product cyanobacterin, which in Nature is produced in small quantities by the cyanobacteria Scytonema hofmanni.

27 May 2022

SARS-CoV-2 genome analysis could boost disease surveillance

Continued monitoring of the evolution of the virus that causes COVID-19 as the pandemic progresses could strengthen disease surveillance systems and aid preparedness for new variants, a study suggests.

27 May 2022

Researchers report novel interactions between the SARS-CoV-2 S protein and estrogen receptor alpha

Researchers profiled the binding sites of the entire SARS-CoV-2 spike protein sequence.

26 May 2022

Researchers discover mechanisms underlying T-cell receptor's immunosuppressive function

Investigators have discovered the mechanisms underlying a T-cell receptor's immunosuppressive function, according to a study published Nature Immunology, findings that may provide insight into the development of novel precision therapeutics for chronic diseases, including cancer.

25 May 2022

Bioinformatics News and Research

Further Reading

Using genomics to restore degraded ecosystems

Rensselaer scientists secure $3.5 million grant to develop a low-dose, oral COVID antiviral drug

Researchers discover two important novel aspects of APOE4 gene in Alzheimer's patients

An integrated molecular diagnostic approach for detecting SARS-CoV-2 variants

Potential SARS-CoV-2 antivirals based on host miRNAs

SARS-CoV-2 variant-specific polymerase chain reaction assay for SARS-CoV-2 genomic surveillance

New approach to quantify tumor-specific total mRNA levels from patient tumor samples

New machine learning algorithm finds a gene signature characteristic of tumors

Abundance of Lactobacillus crispatus linked to lower risk of preterm birth

Genomic analysis provides a deeper understanding of DCIS biology

Discovery may lead to new treatments to reduce inflammation in vitiligo disease

Lack of diversity in genomic research could deprive Africans of life-changing care for chronic diseases

A system for detecting emerging SARS-CoV-2 variants

Aerobic exercise amplifies the effects of immunotherapy to reduce pancreatic tumor growth

New study uncovers the impact of genetic mutations on lifelong blood cell production

Exposure to traffic-related air pollutants linked with pregnancy complications

Researchers gain understanding of biosynthetic mechanisms for producing cyanobacterin

SARS-CoV-2 genome analysis could boost disease surveillance

Researchers report novel interactions between the SARS-CoV-2 S protein and estrogen receptor alpha

Researchers discover mechanisms underlying T-cell receptor's immunosuppressive function

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